Cases reported "Skin Diseases, Parasitic"

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1/8. Cutaneous fascioliasis: a case report in vietnam.

    A 40 year-old woman living in Gialai, Kontum, vietnam, developed a red solid mass in the epigastric region. From ultrasound investigation, liver abscess and myositis of the intercostal muscle was diagnosed. Two weeks after treatment with antibiotics, the mass disappeared, but a migratory track developed in the right upper quadrant of the abdomen. An aspiration of the vesicular end of the serpiginous track showed a light brown, living worm that was later identified as an immature fasciola sp. This is the first case report of cutaneous fascioliasis in the form similar to creeping eruption.
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2/8. Outward migration of gnathostoma spinigerum in interferon alpha treated hepatitis c patient.

    After the first dose injection of pegylated interferon alpha-2b (Peg-IFN alpha-2b) to a HCV infected Thai woman, she developed cyclic painful swelling nodules on right upper quadrant of abdomen and right anterior lower chest wall. The nodules subsided spontaneously within 1-2 days but were recurrent after every Peg-IFN alpha-2b injection. She also experienced acute urticaria. After nine months of therapy, an immature male of G. spinigerum migrated out from the skin nodule shortly after a Peg-IFN alpha-2b injection as scheduled. The worm showed a head-bulb bearing 8 transverse rows of spines which indicated immature stage. It had well defined four pairs of caudal papillae on posterior body part which were used to identify male gender. Painful migratory swelling and urticaria disappeared after the parasite was removed. She was continually treated and had sustained both virological and biochemical responses to HCV treatment. This case demonstrates that the outward migration of G. spinigerum may be stimulated by the injection of Peg-IFN alpha-2b.
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3/8. Disseminated strongyloidiasis presenting as purpura.

    We report a patient with disseminated strongyloidiasis who was being treated with steroids for cerebral edema caused by brain metastases from urinary bladder carcinoma. He had extensive purpura involving the abdomen, arms, and thighs. A skin biopsy specimen showed numerous larvae of strongyloides stercoralis. Subsequently, rhabdoid larvae of S. stercoralis were isolated in the stool and the sputum. The patient died 2 days later despite thiabendazole therapy.
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4/8. dermatitis due to larvae of a soil nematode, Pelodera strongyloides.

    A 6-month-old infant girl was seen because of failure to thrive and hyperpigmented papulonodules on the lower abdomen and thighs. Results of skin biopsy demonstrated dauer larvae of a soil nematode, Pelodera strongyloides, in the dermis. This is the second documented episode of human dermatitis due to this nematode, which more often invades the skin of dogs, cattle, horses, and sheep.
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5/8. gnathostomiasis. Infestation in an Asian immigrant.

    With the recent influx of southeast Asians into the united states, an increased incidence of human gnathostomiasis can be expected. A Laotian woman had had two weeks of pruritus associated with fleeting erythematous patches on her abdomen. A peripheral eosinophilia was present. She withdrew a gnathostoma spinigerum from the skin of her abdomen. gnathostomiasis is endemic in much of asia and causes not only migratory cutaneous swellings with erythema but also serious visceral sequelae such as eosinophilic encephalomyelitis. Excision of the parasite is the treatment of choice when possible.
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6/8. pathology of subcutaneous sparganosis: report of two cases.

    Two cases of subcutaneous sparganosis were discovered at the Taipei Institute of pathology in early spring of 1992. They had been resected under the impression of lipomas of the chest and abdomen. Both lesions contained characteristic plerocercoid larva (sparganum) of spirometra sp., presumably spirometra mansoni. Characteristic tissue reactions included necrosis, granulomatous reaction, and lymphoplasma cell infiltrates with focal collections of eosinophils. Since the worm can be readily dislodged from the tissues, an accurate diagnosis may not be possible in every instance. Thus, the prevalence of the disease may have been underestimated. Consuming raw flesh of infected second intermediate hosts or paratenic hosts and drinking unboiled water contaminated by infected Cyclops seems to favor the endemic occurrence of the disease in taiwan.
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7/8. Ectopic cutaneous schistosomiasis: report of two cases and a review of the literature.

    Two cases of ectopic cutaneous schistosomiasis are described. Both patients presented with abdominal papular skin lesions, which on biopsy were found to contain granulomas with schistosoma mansoni eggs. Twenty-five other cases were retrieved from the literature. Most patients were female, mean age 24.9 year, with a predominance of the white race. The most common localization was anterior thorax and abdomen. Usually, the lesions were asymptomatic. In few cases, however, severe clinical syndromes due to the parasite coexisted, such as transverse myelitis or the acute-toxemic form of the disease. Intestinal infection was not frequently demonstrated in these patients. The importance of the recognition of these cutaneous lesions may rest on the opportunity to provide an etiological diagnosis in these difficult cases.
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8/8. Human gnathostomiasis caused by gnathostoma doloresi, with particular reference to the parasitological investigation of the causative agent.

    gnathostomiasis caused by gnathostoma doloresi Tubangui was observed in a 46-year-old Japanese man, a clerk, who resided in the Fukuoka prefecture of Kyushu district, in southern japan. The first symptom noted by the patient was epigastric pain, which occurred 3 days after he had consumed the raw flesh of a brook trout, oncorhynchus masou masou (Brevoort), from a trout farm in neighbouring Kumamoto prefecture. Three days later, he developed creeping eruptions on his trunk. The eruptions spread and the patient was admitted to hospital 18 days after eating the trout. No nematode larvae were found in any of four skin biopsies collected on admission. However, vesicles appeared on the lower abdomen of the patient 20 days after he had eaten the trout, and a small nematode was removed from one of them. One day after the nematode had been excised, a cutaneous swelling suddenly occurred on the patient's lower left jowl and this persisted for a week. All the skin abnormalities gradually decreased from day 25 post-ingestion and had disappeared by day 30. The isolated nematode was identified as an advanced third-stage larva of G. doloresi, based on its morphology and the number of hooklets on its head-bulb.
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