1/12. Perianal cytomegalovirus ulcer in an HIV infected patient: case report and review of literature.We report the case of a 25-year-old man with acquired immunodeficiency syndrome, presenting with perianal ulcer and diarrhea. He had positive immunocytochemical tests for cytomegalovirus (CMV) in circulating polymorphonuclear cells (PMN). The biopsy specimen was suggestive of CMV infection, and specific immunoperoxidase for CMV antigens positively stained endothelial cells and fibroblasts. In this report we review cutaneous CMV infection in immunocompromised patients.- - - - - - - - - - ranking = 1keywords = immunodeficiency syndrome, immunodeficiency (Clic here for more details about this article) |
2/12. Prolonged herpes zoster in a patient infected with the human immunodeficiency virus.In 1983, varicella zoster virus (VZV) disease was first recognized in the context of infection with the human immunodeficiency virus (HIV). Since that time, there have been many reports discussing the occurrence and clinical manifestations of hepes zoster in HIV-infected patients. We describe the development of prolonged herpes zoster in a patient with acquired immunodeficiency syndrome (AIDS) over the course of 104 days. Viral isolates at the three different clinical stages of the skin lesions were sensitive in vitro to acyclovir, and supposed to be a same strain by polymerase chain reaction (PCR) analysis. We also discuss an effective treatment for prolonged cases of zoster.- - - - - - - - - - ranking = 1.5623617528309keywords = immunodeficiency syndrome, immunodeficiency (Clic here for more details about this article) |
3/12. Resolution of recurrent perianal condylomata acuminata by topical cidofovir in patients with HIV infection.Anogenital condylomata acuminata are the most frequent clinical manifestation of genital human papillomavirus (HPV) infection. association between human immunodeficiency virus (HIV) and HPV infections is frequent (range: 26-60% in males). Topical cidofovir (a nucleotide analogue antiviral drug active against a broad range of dna viruses) is a potential treatment for anogenital warts in immunocompromised patients. We treated three HIV-infected patients with HPV perianal condylomas with topical 1% cidofovir in flexible collodion once a day for 2 weeks. The treatment resulted in complete clearance of the HPV lesions. The patients experienced mild transient erythema without any other side-effects. None of the patients relapsed during the 10-14-month follow-up period.- - - - - - - - - - ranking = 0.11247235056618keywords = immunodeficiency (Clic here for more details about this article) |
4/12. Verrucous lesions secondary to dna viruses in patients infected with the human immunodeficiency virus in association with increased factor xiiia-positive dermal dendritic cells. The Military Medical Consortium of Applied Retroviral research washington, D.C.BACKGROUND: Hyperkeratotic lesions caused by varicella-zoster, herpes simplex, or cytomegalovirus occur in patients infected with human immunodeficiency virus type 1 (hiv-1). We have also observed this type of lesion with molluscum contagiosum. OBJECTIVES: These cases were studied to determine whether there are any pathologic changes unique to these lesions. methods: The cases were studied by routine microscopic examination and immunohistochemistry. RESULTS: Each case showed changes diagnostic of the viral infection, which was confirmed by immunohistochemical stains for herpes simplex and cytomegalovirus. In the dermis there were fewer inflammatory cells than expected, but there was an increase in factor xiiia-positive dendritic cells. CONCLUSION: Varicella-zoster, herpes simplex virus, cytomegalovirus, and molluscum contagiosum can cause verrucous lesions in hiv-1-infected patients. These lesions may be related to an increase in factor xiiia-positive dendritic cells.- - - - - - - - - - ranking = 0.5623617528309keywords = immunodeficiency (Clic here for more details about this article) |
5/12. Recurrent 'sterile' verrucous cyst abscesses and epidermodysplasia verruciformis-like eruption associated with idiopathic CD4 lymphopenia.rupture of follicular (epidermoid) cysts is believed to be the consequence of bacterial infection. We report a 24-year-old man with idiopathic CD4 lymphopenia and chronic mycobacterium avium intracellulare infection who developed multiple, recurring painful abscesses over the distal extremities that increased in number and severity when systemic steroid and interferon-gamma treatment was instituted for interstitial lung disease. Cultures were consistently negative for microorganisms, but pathological examination revealed ruptured epidermoid cyst walls with human papillomavirus (HPV) viropathic changes (keratinocytes with perinuclear halos and abundant basophilic keratohyaline granules). Cutaneous examination showed numerous, widespread flat-topped papules and achromic macules over the extremities, head and neck. Nested polymerase chain reaction analysis for HPV DNA revealed that the abscess-related cyst walls harboured epidermodysplasia verruciformis (EV)-associated HPV types 20, 24, alb-7 (AY013872) and 80. His cutaneous lesions harboured HPV types 3, 8 and 80. Similar to past reports, our patient developed an EV-like eruption in the setting of immunodeficiency. In this instance, EV-associated HPV infection of the follicular infundibular epithelium or pre-existing cysts in the setting of immunodeficiency may have led to cystic growth, rupture and subsequent painful inflammation.- - - - - - - - - - ranking = 0.22494470113236keywords = immunodeficiency (Clic here for more details about this article) |
6/12. Disseminated cutaneous cytomegalic inclusion disease resembling prurigo nodularis in a HIV-infected patient: a case report and literature review.cytomegalovirus infection is common disease but most of the healthy patients are asymptomatic. cytomegalovirus infection is a serious problem in immunocompromised patients particularly in acquired immunodeficiency syndrome. About 90 per cent of patients with AIDS develop active cytomegalovirus infection and up to 25 per cent may experience life threatening infection due to the virus. However, cytomegalovirus cutaneous lesion have rarely been reported. A 40-year-old Thai man presented with multiple prurigo nodularis-like lesions on both legs and feet. The investigation revealed consistent with acquired immunodeficiency syndrome associated with cytomegalovirus cutaneous infection.- - - - - - - - - - ranking = 2keywords = immunodeficiency syndrome, immunodeficiency (Clic here for more details about this article) |
7/12. Chronic hyperkeratotic herpes zoster and human immunodeficiency virus infection.A patient with human immunodeficiency virus infection had hyperkeratotic papules in the T 11 and T 12 dermatomes in which she previously had papulovesicular herpes zoster. Findings of a biopsy specimen and viral culture of these papules subsequently revealed varicella-zoster that eventually responded to prolonged high-dose acyclovir therapy and debridement. A review of reported cases of hyperkeratotic varicella-zoster infections is presented, in addition to our recommendations for the treatment of varicella-zoster infection in patients who have acquired immunodeficiency syndrome.- - - - - - - - - - ranking = 1.5623617528309keywords = immunodeficiency syndrome, immunodeficiency (Clic here for more details about this article) |
8/12. Acute exanthem and pancreatic panniculitis in a patient with primary HIV infection and haemophagocytic syndrome.We report a patient with an acute infection with the human immunodeficiency virus (HIV), who initially presented due to a mononucleosis-like illness that included a rash on the upper trunk and limbs, and oral ulceration. The patient developed a haemophagocytic syndrome with severe systemic involvement. Three weeks after the initial presentation, lesions of a pancreatic panniculitis appeared on both legs.- - - - - - - - - - ranking = 0.11247235056618keywords = immunodeficiency (Clic here for more details about this article) |
9/12. Herpes zoster peripheral ulcerative keratitis in patients with the acquired immunodeficiency syndrome.The purpose of this study was to describe the clinical characteristics and course of peripheral ulcerative keratitis (PUK) secondary to herpes varicella-zoster virus in patients with the acquired immunodeficiency syndrome (AIDS). Three AIDS patients with ocular herpes zoster infection (mean age at onset, 33.0 years; range, 30-42) developed PUK. The three patients had skin involvement, and two of them had bilateral keratouveitis. All were treated with high-dose oral acyclovir (4 g/day) with or without topical antiviral therapy. Two of the patients responded well to oral acyclovir, but one of them stopped the treatment, and bilateral progressive outer retinal necrosis and lethal encephalitis developed. The third patient had a recurrent episode of inflammation with PUK, extensive stromal scarring, and deep neovascularization. AIDS patients with herpes varicella-zoster virus infection may have severe and protracted corneal manifestations, including PUK. The correct diagnosis and aggressive early long-term systemic antiviral treatment must be instituted to control inflammation, ulcer progression, and complications.- - - - - - - - - - ranking = 5keywords = immunodeficiency syndrome, immunodeficiency (Clic here for more details about this article) |
10/12. Presumed bilateral herpes zoster ophthalmicus in an AIDS patient: a case report.A 31-year-old man with the acquired immunodeficiency syndrome presented with herpes zoster ophthalmicus on the right. Five days after he began treatment for the zoster pseudodendrites and skin lesions, he developed superficial punctate keratitis, uveitis, and crusting skin lesions in the left eye. After treatment, the ocular lesions resolved in both eyes without incident. The bilateral manifestation of herpes zoster ophthalmicus is a result of the increased severity associated with immunosuppression caused by the human immunodeficiency virus.- - - - - - - - - - ranking = 1.1124723505662keywords = immunodeficiency syndrome, immunodeficiency (Clic here for more details about this article) |
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