1/8. Chronic sclerosing sialadenitis of the submandibular and parotid glands: a report of a case and review of the literature.Chronic sclerosing sialadenitis (also known as Kuttner tumor) is a chronic inflammatory condition of the salivary glands, first described by Kuttner in 1896. Clinically, the disease cannot be distinguished from a true neoplasm. The submandibular gland is affected more commonly than any other salivary gland. This report is of a case of widespread swelling of the salivary glands in which histologic features of chronic sclerosing sialadenitis were seen in the submandibular and parotid glands. The etiology, pathogenesis, and differential diagnosis of this disease and the clinical outcome of this case are discussed and presented.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
2/8. Bilateral Kuttner tumor of submandibular glands; a case report and review of the literature.Kuttner tumor is a relatively uncommon disease of the salivary gland. It is also known as chronic sclerosing sialadenitis or cirrhosis of the submandibular gland. The examination of the submandibular gland characterizes clinically by a firm swelling of the gland, and histologically by progressive periductal sclerosis, dense lymphocytic infiltration with lymphoid follicle formation, reduction of the secretory gland parenchyma and fibrosis. Clinical, cytologic, histopathologic and immunohistopathologic features with briefly reviewed relevant literature describing 231 cases are discussed. The patients with the mean age of 44 years (range 13-81 years) had submandibular masses known to be present for 1 week to 55 years (mean 23.2 years). There is a slight predilection for occurrence in men. This is the first reported description of bilateral Kuttner tumor of submandibular glands in thailand. It was initially diagnosed as a primary submandibular gland neoplasm that fine needle aspiration revealed to be chronic sialadenitis.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
3/8. Kuttner's tumor of the submandibular glands: report of five cases with fine-needle aspiration cytology.Kuttner's tumor (KT) is a benign tumor-like lesion of the salivary gland that mimics neoplasm clinically because of presentation as a hard mass. Recently, the histomorphological and immunohistochemical findings of this lesion have been analyzed, and differential diagnostic problems relating to salivary gland lymphoma have been discussed. However, currently there is little information on the cytological findings of those lesions. We present cytological findings from five such cases using fine-needle aspiration cytology (FNAC). FNAC of this lesion may present a diagnostic challenge to the cytologist as lesions share some cytologic features with inflammatory process containing numerous lymphoid cells. Smears obtained from two cases contained moderate to large numbers of lymphoid cells without definite cytological atypia, scattered ductal structures, and acinar cell clusters. The remaining three cases showed low cellularity probably attributable to fibrosis that made it difficult to aspirate the cellular element. FNAC findings of scattered ductal structures surrounded by collagens and infiltrated by a mixed population of lymphoid cells, not specific for KT, are highly suggestive of the diagnosis with the appropriate clinical findings. However, a portion of cytological specimens of KT containing relatively large numbers of lymphoid cells should be differentiated from malignant lymphoma arising from the submandibular gland.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
4/8. diagnosis of acute maxillofacial infections: the role of computerized tomography.Most acute maxillofacial infections are diagnosed by conventional dental and maxillofacial radiographic techniques. Computed tomography has greatly improved our ability to evaluate infections of the maxillofacial region that originate or extend into the contiguous soft tissues and paranasal sinuses. Four cases in which computed tomography facilitated diagnosis and treatment of advanced infections of the maxillofacial region are presented. In one case an underlying neoplasm was identified.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
5/8. A mucocele of the submandibular gland.We encountered an unusual case of a mucocele arising from the submandibular gland. Among the limited number of cystic salivary gland neoplasms reported in the literature, there have been no reports, to our knowledge, of a similar cystic lesion. The unique characteristics of this mass permitted definitive diagnosis by computed tomographic scanning.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
6/8. Chronic sialadenitis of the submandibular gland (so-called Kuttner tumor).Two cases of chronic sialadenitis of the submandibular gland (so-called Kuttner tumor) are reported. Clinically, they are asymptomatic except for firm swellings which are similar to neoplasms. light microscopic observations revealed that the lesion is characterized by various degrees of atrophy and/or destruction of acini, infiltration of inflammatory cells, periductal fibrosis and lymph follicle formation. With the electron microscope, a marked increase of collagen fibers are observed throughout the gland parenchyma, and the secretory granules of acinal cells in the remaining acini remarkably decreased in number. We suggest that an autoimmune mechanism may play a role in case 1 and that an ascending infection through the duct system may be a main factor in case 2.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
7/8. Inflammatory pseudotumor in the submandibular region. Clinicopathologic study and review of the literature.A rare case of right submandibular inflammatory pseudotumor in a 63-year-old man is reported. The tumor appeared as a symptomless swelling in the submandibular region and resembled a malignant neoplasm on computed tomographic and magnetic resonance images. Surgical resection was required. The pertinent English and Japanese literature is reviewed, and histologic and electron microscopic findings are discussed.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |
8/8. Oral inflammatory pseudotumour: immunohistochemical investigation of a case involving the submandibular gland and review of the literature.Inflammatory pseudotumours (IPs) are rare lesions. Most commonly reported in the lung, they are almost ubiquitous, but few oral cases have been described. Their rapid growth, local invasiveness and recurrence, and their ultrasound, computed tomography (CT) and magnetic resonance imaging (MRI) aspects are confusing and mimic benign or malignant neoplasms. Their recognition and distinction from malignant tumors is of importance but their histopathological diagnosis may represent a challenge. In the case reported involving the submandibular gland, the spindle cells had the immunohistochemical profile of myofibroblasts, broader cells with a larger nucleus were CD68 and/or Mac387 positive and the dense plasmacytic infiltrate was polyclonal. Histopathology of IPs covers a spectrum of appearances according to the cellularity and the degree of fibrosis. The recognition of a variable mixture of three main cell types: histiocytes or macrophages, myofibroblasts or fibroblasts and abundant plasma cells, with low mitotic activity and absence of cytological abnormalities in an ill circumscribed and rather fibrous lesion is recommended for the diagnosis of oral IP.- - - - - - - - - - ranking = 1keywords = neoplasm (Clic here for more details about this article) |