1/14. A case of Unna-Thost disease accompanied by epidermophyton floccosum infection.We report herein a case of 61-year-old man with Unna-Thost disease (nonepidermolytic hereditary palmoplantar keratoderma) who had been suffering from refractory dermatophyte infection. Diffuse palmoplantar hyperkeratosis developed in his infancy. Coarse scaling, fissures, marked erythema, and nail deformities appeared in his early adult life. Microscopic examination revealed fungal elements in scales and nail particles. Cultures of those scales isolated epidermophyton floccosum. Genealogical study demonstrated that his mother, sister, brother, daughter, and niece had had similar tylosis, and all of the affected individuals except his daughter had been proved to have E. floccosum or trichophyton rubrum infection. Oral itraconazole (100mg/day) was highly effective in treating his dermatophytosis without any adverse effects. Scaling, fissures and underlying erythema disappeared within four months.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
2/14. The definition of trichophyton rubrum syndrome.Although chronic widespread dermatophyte infection is reported widely in the literature, neither a uniform nomenclature, nor even a clear definition of this syndrome have been established so far. Thus, we suggest trichophyton rubrum syndrome (TRS) for denomination and define the following obligatory clinical and mycological criteria for TRS. (A) skin lesions at the following four sites: (1) feet, often involving soles; (2) hands, often involving palms; (3) nails; and (4) at least one lesion in another location than (1) (2) or (3), except for groins. (B) Positive microscopic analyses of potassium hydroxide preparations of skin scrapings in all four locations. (C) Identification of trichophyton rubrum by cell culture at three of the four locations at least. For diagnosis of TRS the criteria (A) and (B) and (C) have to be fulfilled. This standardization is a prerequisite for further investigations of underlying mechanisms of this disease. The typical clinical pattern of TRS is illustrated by the presentation of two paradigmatic cases.- - - - - - - - - - ranking = 0.5keywords = palm (Clic here for more details about this article) |
3/14. Dermatophyte infection in ichthyosis vulgaris.A 31-year-old male who had been suffering from ichthyosis vulgaris developed hyperkeratosic lesions on the palms and soles and ungual alterations of both hands and feet. These lesions were resistant to topical corticosteroid and emollient cream treatments and were found to be caused by trichophyton rubrum. association of ichthyosis vulgaris and dermatophytosis--both very common disorders--is to our knowledge a very rare event.- - - - - - - - - - ranking = 0.5keywords = palm (Clic here for more details about this article) |
4/14. Enlarging pigmented patches on the hand.This case illustrates the clinical and pathological features of tinea nigra. awareness of the characteristic features of this cutaneous infection, especially in areas where the organism is endemic, can ultimately lead clinicians to the appropriate diagnosis. If tinea nigra should be considered in the differential diagnosis of palmoplantar pigmentation, potassium hydroxide (KOH) preparation may facilitate the diagnosis.- - - - - - - - - - ranking = 0.5keywords = palm (Clic here for more details about this article) |
5/14. tinea manuum bullosa.We report a case of tinea manuum bullosa in a 36-year-old male, a crop and livestock farmer by trade. The lesion, resembling contact dermatitis, was located in the palm of the right hand. We isolated trichophyton verrucosum. No other skin lesion was detected. blood chemistry and immunology test results were normal. Treatment with terbinafine 250 mg day(-1) led to clinical and mycological healing.- - - - - - - - - - ranking = 0.5keywords = palm (Clic here for more details about this article) |
6/14. A case of tinea nigra palmaris in Okinawa, japan.We report a case of tinea nigra on the left palm of a 13-year-old girl. She had noticed a pigmented, asymptomatic macule on the left palm approximately 4-5 years prior to her first visit to our hospital. The color of the lesion tended to change before and after a bath; it became lighter after a bath and darkened some time later. physical examination revealed that the macule was 4 cm x 5 cm in size, dark brown in color and irregularly shaped. Direct potassium hydroxide (KOH) microscopic examination from skin scrapings revealed branched brown hyphae with light brown septa. A fungal culture on Sabouraud's agar media produced wet, medium brown, yeast-like colonies, the surface of which later became black and shiny. A slide culture disclosed light brown, elliptic or peanut-shaped conidia comprised of one to two ampullaceous cells. Scanning electron microscopic examination of the conidia showed both annellation conidia with lunate bud scars and sympodial conidiogenesis. Using extracted dna from separately cultured fungi, we performed polymerase chain reaction with the primers specific to Hortaea werneckii. The results showed positive bands. We performed direct sequencing with the dna segments from the positive bands. The causative fungus in our case was determined to be type C of H. werneckii on the grounds of the base sequences obtained. The final diagnosis of the present case was made as tinea nigra by H. werneckii. We also report a brief survey of all the cases of tinea nigra reported in japan to date.- - - - - - - - - - ranking = 3keywords = palm (Clic here for more details about this article) |
7/14. Rapid treatment of tinea nigra palmaris with ciclopirox olamine gel, 0.77%.A 48-year-old white woman presented with the abrupt onset of an asymptomatic but cosmetically distressing eruption on the palm. physical examination disclosed a 2.5 x 2.0-cm macular brown patch on the central left palm (Figure 1). potassium hydroxide examination revealed brown-pigmented, septate, branching filamentous hyphae. Clinical and microscopic findings were classic for tinea nigra palmaris. Medical, family, and social history were all unremarkable. The patient applied ciclopirox olamine gel, 0.77% b.i.d. for 3 days. Following this brief therapeutic intervention, the lesion resolved completely (Figure 2). She remained clear during the ensuing 14-month follow-up.- - - - - - - - - - ranking = 3.5keywords = palm (Clic here for more details about this article) |
8/14. psoriasis and hereditary palmoplantar keratoderma complicated with a dermatophyte infection. Case report.In a 29-year-old woman suffering from hereditary palmoplantar keratoderma of the Unna Thost variety, psoriasis appeared at an age of 28 years. The keratoderma on the soles was complicated with a dermatophyte infection, which made the differential diagnosis towards psoriasis difficult. Histopathologic examination of punch biopsy from the soles showed no conclusive signs of psoriasis. An increased thickness of the horny layer, which in PAS staining showed fungus hyphae, was found.- - - - - - - - - - ranking = 2.5keywords = palm (Clic here for more details about this article) |
9/14. Widespread cutaneous candidiasis and tinea infection masking mycosis fungoides.A 71-year-old female with a widespread double mycotic infection caused by C. Albicans and T. rubrum was discovered to be suffering from mycosis fungoides. Clinically she was found to have large, polycyclic erythematous plaques with scaly, slightly infiltrated borders, covering almost all areas of the glabrous skin, and also involving the scalp (with no hair penetration), the soles and palms, toe-webs, finger and toe nails; there was also perleche and oral thrush. Cultures yielded C. albicans from most of the skin lesions, from the scalp, mouth, finger nails and urine and stool specimens, and T. rubrum from intermingled skin specimens, from the palms and soles and toe-nails. blood culture was negative as were intracutaneous tests with fungal antigens and tuberculin. Histological examination confirmed the fungal invasion of the horny layer and at the same time revealed an underlying pathologic picture of mycosis fungoides, the lesions having been masked by the mycotic eruption. Intensive cytostatic and antifungal therapy led to a transient improvement but shortly thereafter there was a relapse of the fungal and lymphoproliferative manifestations and the patient died in septic shock.- - - - - - - - - - ranking = 1keywords = palm (Clic here for more details about this article) |
10/14. Treatment of tinea nigra palmaris with miconazole.A patient with tinea nigra palmaris was successfully treated with 2% miconazole nitrate cream. in vitro studies demonstrated sensitivity of the causative agent, exophiala werneckii, to this antifungal agent.- - - - - - - - - - ranking = 2.5keywords = palm (Clic here for more details about this article) |
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