1/9. A case of black dot ringworm with a review of Japanese cases.Black dot ringworm (BDR), caused by trichophyton violaceum var. glabrum (T. glabrum), was observed in a 28-year-old Japanese female who had been treated with prednisolone (22.5 mg/day) for systemic lupus erythematosus. It was successfully treated with oral terbinafine (125 mg/day) for 12 weeks. The causative fungus was identified by molecular analysis as well as morphological and biochemical examination. The chitin synthase 1 (CHS1) gene cleavage pattern of the clinical isolate with restricted enzyme HinfI was identical to that of T. violaceum. We reviewed previous reports of BDR to determine the historical trend of this infection in japan. Since 1974, 93 Japanese cases have been reported. The age distribution was bi-modal: the higher peak consisted of children (aged 0-15 years), and the lower peak was composed of the elderly (aged 60-75 years). In the elderly group, females were predominant (M:F=1:22, p<0.001). T. violaceum, including T. glabrum, was identified as the most common causative fungus of BDR (75.3%). Sixty percent of cases showed slight erythema. In 8 families, 16 cases were found to be intrafamilial infections. A history of previous steroid treatment was described in about 40%.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
2/9. Inflammatory tinea capitis caused by microsporum gypseum in a five-year-old girl.An otherwise healthy five-year-old girl presented for evaluation of a large patch of erythematous scaling alopecia on the vertex of her scalp. Previous attempts to treat this with various topical agents resulted in no improvement. Our evaluation included examination of fungal cultures, which grew out a colony with characteristic morphology of microsporum gypseum, supported by lactolphenol blue tease mounts, demonstrating the characteristic conidia for this fungus. Treatment was begun with oral griseofulvin, and evidence of inflammation resolved along with conversion to negative cultures for M. gypseum, although an area of scarring alopecia from the kerion remains. The epidemiologic basis, clinical presentation, differential diagnosis, evaluation, and treatment principles for this important geophilic organism are reviewed. physicians need to be aware of this agent of tinea capitis, since it is destructive and only responsive to oral therapy.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |
3/9. tinea capitis caused by microsporum praecox in a patient with sickle cell anaemia.microsporum praecox Rivalier ex Padhye, Ajello et McGinnis is the validated name for the taxon originally published as Sabouraudites praecox Rivalier. We describe here the first case of small-conidial, ectothrix type hair invasion caused by M. praecox in an adult woman from oklahoma, U.S.A., suffering from sickle cell anaemia. This fungus is now being encountered with greater frequency as an etiologic agent of ringworm infection.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |
4/9. Fungal kerion--total scalp involvement due to microsporum canis infection.We report the case of a 5-year-old girl who developed a remarkably extensive kerion of the scalp due to microsporum canis infection. Total scalp involvement of this severity and prolonged duration is now unusual, but there has been surprisingly little residual cicatricial alopecia. microsporum canis does not respond well to ketoconazole, and griseofulvin remains the drug of choice for dermatophyte infections involving hair; a prolonged course may be necessary. This case also demonstrates the benefit of corticosteroids for certain cases of inflammatory ringworm where the host's response to the fungus is exceptionally marked.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |
5/9. The infected hairs of tinea capitis due to microsporum canis: demonstration of uniqueness of the hair cuticle by scanning electron microscopy.Scanning and transmission electron microscopic studies were done on scalp hairs of four patients infected with ectothrix microsporum canis. Both freeze fracture and cross-sectioning of hairs revealed a thick sheath of fungal spores encircling the hair shaft beneath an intact cuticle. These spores were not visible on surface inspection but became apparent only where the cuticle had been rubbed off or broken. Daily selenium sulfide shampoos removed all of the spores from these sites. The cuticle is viewed as being an effective barrier to the penetration of fungi, so that the hair is vulnerable to fungus infection only deep within the hair follicle below the level of the mature cuticle. Once the fungus enters the hair cortex just above the hair bulb, it produces myriads of spores that remain trapped and hidden beneath the cuticle for the length of the intact hair.- - - - - - - - - - ranking = 1keywords = fungus (Clic here for more details about this article) |
6/9. tinea capitis due to microsporum canis in infants.Three cases of scalp involvement by M. canis in infants are briefly reported. The first was a 2-month-old female with a few erythematous spots on the scalp, the second an 8-month-old male with lesions resembling seborrhoeic dermatitis and the third an 11-month-old male having areas of folliculitis of a kerion type. The father of the second case was found to have a tinea barbae infection due to the same fungus. Stray kittens were the most probable source of infection in all these cases.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |
7/9. Dermatophyte pseudomycetoma: a case report.A 25-year-old man presented with several prominent subcutaneous masses in the occipital region of the scalp. He had a long history of tinea capitis and tinea corporis infection. Histopathology of the occipital lesions showed mycelial aggregates in the deep dermis and subcutis. Cultures of the excised material and superficial scales grew a fungus identified as microsporum ferrugineum. We propose the term 'dermatophyte pseudomycetoma' to describe this distinctive mycosis.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |
8/9. tinea capitis in adults.Invasion of keratin of the hair by dermatophytes is a rare event after puberty. A study of 2200 patients affected by various mycotic cutaneous infections during 6 years of observation brought to our attention three cases of tinea capitis in adults. Confirming the studies of other authors, we also found that this disease mostly affected females. In all cases the isolated aetiological agent was microsporum canis, the fungus species most frequently responsible for tinea capitis in italy.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |
9/9. Kerion-like tinea capitis and barbae caused by microsporum gypseum in israel.Four cases of hair invasion by microsporum gypseum are reported. In three the scalp was involved and in one, the beard. All presented a kerion type of invasion. In 3 cases hair penetration was of the ectothrix type, while in one case the kerion of the scalp resembled the type of invasion seen in T. schonleini infection. None of the invaded hairs showed fluorescence in wood's light. The soil was the source of infection in 3 patients, the fungus having been isolated from soil samples collected in the vicinity of the houses of these patients through the hair bait method. In one case the source of contamination was the family dog, in which scaly, alopecic, follicularlike lesions caused by the same agent were found.- - - - - - - - - - ranking = 0.5keywords = fungus (Clic here for more details about this article) |