1/14. Giant juvenile xanthogranuloma of the tongue.Juvenile xanthogranulomas (JXGs) are rare, benign, fibrohistiocytic lesions. They usually appear as one or more cutaneous papules on the head, neck, or trunk in infants. Twelve cases of oral JXGs have been reported, four of which involved the tongue. We present a 6-year-old girl with a large tongue mass diagnosed as JXG after an excisional biopsy. Histological and immunohistochemical staining results are presented. This is the first reported case of a giant oral JXG. A review of the literature on these unusual lesions is presented, along with discussion of their differential diagnosis and key aspects of the patient's evaluation, management, and pathological diagnosis.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
2/14. tongue necrosis provoked by ergotamine tartrate and disclosing a giant cell arteritis.A case of tongue necrosis induced by ergotamine tartrate is reported in a patient who was suffering from an unknown giant cell arteritis (GCA). The role of ergotamine in provoking tongue necrosis in temporal arteritis has only infrequently been considered. The hypothesis concerning ergotamine-induced vasospasm potentially being able to trigger a tongue necrosis in GCA is supported by the present case. This unusual complication warns us against uncritical prescription of this drug for elderly people suffering from migraine without considering GCA.- - - - - - - - - - ranking = 5keywords = giant (Clic here for more details about this article) |
3/14. Management of a giant lymphatic malformation of the tongue.Lymphatic malformations can occur anywhere in the head and neck, and when they do so in the oral cavity, they can present a potential hazard to the airway. We describe a 4-year-old girl with a giant lymphatic malformation of the tongue and neck. This report illustrates the particular difficulties that may be encountered in cases involving giant lymphatic malformations of the cervicofacial region in the pediatric population. An overview of the etiology, diagnosis, histology, and options for the management of such lesions is outlined.- - - - - - - - - - ranking = 6keywords = giant (Clic here for more details about this article) |
4/14. necrosis of the tongue in a patient with intestinal infarction.A patient with a rare combination of bilateral lingual necrosis and intestinal infarction, caused by giant cell arteritis, is described and the literature reviewed.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
5/14. A denture complication: sarcoid-like foreign body granulomas of the tongue.sarcoidosis in the oral cavity occurs extremely rare (there have been described only 47 cases in the literature) and is almost always doubtful. We describe a protruding painful nodule (1 cm) on the apex of the tongue of a 65-year-old female, adjacent to the site of irritation of a new denture. Histologically it was confluent mass of non-caseous granulomas, rich in Langhans' cells. silver impregnation showed them stamped out as in sarcoidosis. Corticosteroids proved to be ineffective and the therapy was discontinued because of the concomitant diabetes. Six months later, similar nodules reappeared on the same place. When examined in polarized light these giant cells were found to be of the foreign body type, each of them containing phagotized particles displaying bright yellow and dark green colour. We assume a sarcoid-like reaction of traumatic origin. There was no recurrence of the condition after removal of the denture.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
6/14. Lingual ulcer as the only sign of recurrent mycobacterial infection in an hiv/AIDS-infected patient.The report describes an hiv/AIDS patient seen at a referral center in mexico City, in whom a mycobacterial infection in the oral mucosa, probably tuberculosis (TB) was identified. The purpose is to describe the clinical and histological findings in an hiv-infected patient, who after being treated successfully for tuberculous lymphangitis 4 years ago, presented with a lingual ulcer as the only suggestive sign of recurrence of mycobacterial infection, probably M. tuberculosis. A 39-year-old man seen in the hiv clinic of the Instituto Nacional de Ciencias Medicas y Nutricion "Salvador Zubiran" in mexico City since 1991 for hiv infection. In 1999 the patient developed tuberculous lymphangitis; he was managed with a 4-drug regimen for 12 months, with improvement of local and systemic symptoms. In May of 2003, the patient presented a painful superficial lingual ulcer, 0.7 cm in diameter, well circumscribed, crateriform with slightly elevated, irregular and indurated borders, of 4 months duration. The histopathological examination showed chronic granulomatous inflammation with giant multinucleated cells, suggestive of mycobacterial infection, and recurrence of TB was considered. rifampin, isoniazide, pyrazinamide, ethambutol and streptomycin were administered. The lingual lesion improved with partial healing at the first week and total remission at 45 days after the beginning of the antituberculous treatment. In June, 2003, the patient began highly active antiretroviral therapy (HAART) that included two NRTIs and one NNRTI. At 7 months of follow-up, the patient remains free of lingual lesions. The particularity of the present case is that the lingual ulcer was the only sign of infection by mycobacteria, suggestive of TB, in an hiv/AIDS patient that probably represented a recurrence of a previous episode.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
7/14. Tuberculous ulcer of the tongue: a case report.A 33-year-old male patient was admitted to our hospital with a painless ulcer on the tongue. The lesion was 2 x 3 cm in size, necrotic, and whitish in the anterior part of the ventral surface of the tongue. On further investigation, pulmonary tuberculosis was diagnosed. Cultures of the biopsy specimen and the sputum revealed acid fast bacilli. Histopathologic examination of the biopsy specimen showed tubercles consisting of epithelioid granulomas with caseous necrosis and Langhans giant cells. The lesion was thought to be an extrapulmonary manifestation of pulmonary tuberculosis. Antituberculous therapy was initiated and the ulcer regressed after two months. In the differential diagnosis of nonhealing oral ulcers, tuberculosis should also be considered, especially in patients living in a high risk country for tuberculosis.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
8/14. Ulceration and necrosis of the tongue due to giant cell arteritis.A case is reported of giant cell arteritis in a 74-year-old woman, complicated by ulceration and necrosis of the tongue. During steroid treatment recovery was observed.- - - - - - - - - - ranking = 5keywords = giant (Clic here for more details about this article) |
9/14. Lingual claudication and necrosis as a complication of giant cell arteritis.A case of lingual claudication and necrosis of the tongue due to giant cell arteritis, treated by a high dose of prednisolone, is reported.- - - - - - - - - - ranking = 5keywords = giant (Clic here for more details about this article) |
10/14. Temporal arteritis and gangrene of the tongue.A 69-year-old woman, suspected of having polymyalgia rheumatica, was biopsied from the temporal artery to establish the diagnosis. Six hours after the biopsy, she developed progressive gangrene of the tongue and the floor of the mouth, and intensive steroid therapy was initiated. The histological examination of the biopsy revealed giant-cell arteritis. biopsy or other manipulation of the artery is suggested to be the cause of exacerbation of the arteritis locally. Steroid treatment is proposed in all cases prior to the biopsy. Other studies have not shown that the possibility of obtaining a positive histological diagnosis is reduced during or after steroid treatment. A review of the literature on gangrene of the tongue is given.- - - - - - - - - - ranking = 1keywords = giant (Clic here for more details about this article) |
| | Next -> |