Cases reported "Tongue Diseases"

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1/7. Case report: Oral pemphigus vulgaris with multiple oral polyps in a young patient.

    A rare case of oral pemphigus vulgaris is presented, which developed initially in a 9-year old Jordanian male. The disease was not well controlled with immunosuppressive therapy and was complicated by the development of multiple oral polyps approximately one year after the onset of symptoms. These lesions were smooth, painless and located particularly on the upper labial gingiva, the labial and buccal mucosae and the tongue. disease activity continued for approximately nine years until the patient was referred to an oral medicine specialist. Histological examination of the polyps revealed exuberant granulation tissue. Adjustment of the steroid dosage lead to resolution of the oral symptoms and the polyps reduced in number and in size. This case highlights the occurrence of pemphigus vulgaris in young patients, illustrates a rare complication of persistent ulcero-inflammatory disease and emphasises the importance of specialist referral in the management of oral disease.
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2/7. Oral verruca vulgaris: report of a rare case.

    The common wart or verruca vulgaris are lesions of childhood caused by HPV 2, 4, and 40. These are benign, elevated, firm nodules with characteristic papillomatous surface projections. The most common site of occurrence is the finger. Oral lesions are relatively rare and are usually caused by auto inoculation from lesions on the fingers and hands. We herewith report a case of oral verruca vulgaris that occurred in a middle-aged individual without any wart like lesions elsewhere in the body.
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3/7. pemphigus vulgaris in a juvenile patient: case report.

    pemphigus vulgaris is a rare cause of oral mucosal ulceration that mainly affects middle-aged adults; the oral lesions of pemphigus are associated with cutaneous manifestations. This article reports a case of oral phemphigus vulgaris in a 17-year-old girl without any cutaneous lesions. After seven months of steroid therapy, the disease was controlled. Early recognition of this disease may prevent delayed diagnosis and incorrect treatment.
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keywords = vulgaris
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4/7. pemphigus vulgaris, an overlooked disease in young adults.

    Two cases of pemphigus vulgaris occurring in young men, aged 24 and 29, are presented. Prior to referral, each patient had persistent oral vesiculobullous and ulcerative mucous membrane lesions for at least six months and was treated with multiple courses of antibiotics and mouthwashes. On initial examination, both patients had the characteristic oral vesiculobullous lesions of pemphigus. A biopsy specimen of an intact vesicle confirmed the diagnosis.
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keywords = vulgaris
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5/7. pemphigus vulgaris--the potential for error: a case report.

    The importance of correlation, referral, and collaboration between dermatology, or any other medical department, and the oral health profession is reported through a case presentation. A case of pemphigus vulgaris diagnosed from a tongue biopsy and confirmed by immunofluorescence is reported. The patient was treated for actinic keratosis of the scalp for 16 months due to inadequate biopsy material. The diagnostic value of proper biopsy material is stressed. The clinical manifestations leading to a misdiagnosis between actinic keratosis and pemphigus vulgaris are discussed.
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keywords = vulgaris
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6/7. Use of topical cyclosporin in oral pemphigus.

    The use of systemic cyclosporin in the treatment of pemphigus is well recognized. Oral lesions in pemphigus vulgaris are common but can be very difficult to treat. Short use of topical cyclosporin has been reported in a few cases of oral pemphigus. We report the successful use of topical cyclosporin for several years in a patient with debilitating oral pemphigus in whom systemic immunosuppressive agents and topical steroids had been ineffective and in whom cyclosporin was used not only to induce but also to maintain remission.
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keywords = vulgaris
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7/7. pemphigus vegetans-Neumann variant associated with intranasal heroin abuse.

    pemphigus vegetans is variant of pemphigus vulgaris accounting for 5% of all patients with pemphigus disorders. We describe a case of pemphigus vegetans-Neumann type associated with intranasal heroin abuse, restricted to the modified mucous membranes. The results of routine histology and direct and indirect immunofluorescence studies confirmed the diagnosis. The patient responded to oral prednisone of 40 mg daily for 1 month, followed by reduction to a maintenance dose of 15 mg daily. A complete remission was sustained for 6 months. The relationship between intranasal heroin use and the development of pemphigus vegetans remains uncertain but appears to be an intriguing possibility in this patient.
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keywords = vulgaris
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