Cases reported "Trichomonas Vaginitis"

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1/12. trichomonas vaginalis in a perinephric abscess. A case report.

    A patient with chronic vulvo-vaginitis due to trichomonas vaginalis, and obstructive uropathy associated with renal calculi, developed a perinephric abscess following trauma incurred in a motorcycle accident. T. vaginalis was seen on smear and cultured from the purulent drainage from the perinephric abscess. Although T. vaginalis is commonly pathogenic only to the lower genito-urinary system, the upper urinary tract may very rarely be involved by ascending infection. If this protozoan spreads to extraluminal sites the inflammatory potential is marked, as has been found in animals with experimental infection. Examination of a fresh smear of pus may be critically important in the diagnosis of closed-space infections of unknown etiology.
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keywords = vaginitis
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2/12. Nitroimidazole-resistant vaginal trichomoniasis treated with paromomycin.

    A 33-year old woman with nitroimidazole-resistant vaginal trichomoniasis is described. She was treated with intravaginal paromomycin (500 mg daily for 2 days). This cured the trichomoniasis but resulted in severe local side effects. paromomycin may be useful for difficult cases of nitroimidazole-resistant trichomonas vaginalis vaginitis. The exact dosage still has to be determined.
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keywords = vaginitis
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3/12. Late recurrence of resistant trichomonas vaginalis vaginitis: relapse or re-infection?

    Distinguishing between re-infection and relapse of trichomonas infections is often a difficult task in the clinical setting. The chronicity of trichomonas infections and the ongoing sexual activity are two confounding factors. We present a patient with recurrent resistant vaginal trichomoniasis shortly following a sexual contact with an untreated partner after a complete response to treatment with tinidazole for nine months. We hypothesise that re-infection occurred from the asymptomatic partner who was an untreated chronic carrier of resistant trichomonas in the urogenital tract.
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ranking = 4
keywords = vaginitis
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4/12. Successful response of metronidazole-resistant trichomonal vaginitis to tinidazole. A case report.

    Treatment of metronidazole-resistant trichomonas vaginalis infection is complicated by the lack of an effective alternative therapeutic regimen. Data on the susceptibility of the organism to metronidazole and other nitroimidazoles are important in managing intractable cases. A case of trichomonal vaginitis with true resistance to metronidazole that responded to treatment with tinidazole is reported.
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ranking = 5
keywords = vaginitis
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5/12. Vaginitis emphysematosa. A report of four cases.

    It has been hypothesized that vaginitis emphysematosa is a manifestation of trichomonal or gardnerella infection. In support of this etiologic concept, four cases of the disorder are described showing the apparent curative effect of treating the associated infection. The linkage of these and other reported cases with conditions of impaired immunity suggests that immunologic factors are involved in the pathogenesis.
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ranking = 1
keywords = vaginitis
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6/12. Transvaginal-peritoneal migration of trichomonas vaginalis as a cause of ascites. A report of two cases.

    Genital tract colonization with trichomonas vaginalis usually results in vaginitis without systemic manifestations. There are only four recorded cases of Trichomonas recovered from pelvic organs or peritoneal fluid. This report describes two additional women in whom motile flagellate organisms were recovered from abdominopelvic ascites. We hypothesize that an ascending trichomonal infection may have played an etiologic role in the development of their acute disease.
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ranking = 1
keywords = vaginitis
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7/12. Persistent vaginitis caused by metronidazole-resistant trichomonas.

    Persistent trichomonal vaginitis is usually considered the result of either patient noncompliance with therapy or reinfection. Drug-resistant trichomoniasis may also cause continued infection despite repeated courses of conventional metronidazole therapy. We report two cases of exceptionally persistent and prolonged infection despite repetitive and varied treatments, including parenteral metronidazole. An unconventional approach combining oral and topical therapy resulted in clinical and microbiologic cure in both cases.
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ranking = 5
keywords = vaginitis
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8/12. Failure of mebendazole to cure trichomonal vaginitis resistant to metronidazole: case reports.

    After a recent report showing the in vitro susceptibility to mebendazole of a strain of trichomonas vaginalis that was resistant to metronidazole, we present two cases of metronidazole resistant infection, both of which failed to respond to oral mebendazole.
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ranking = 4
keywords = vaginitis
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9/12. Trichomonal vaginitis refractory to treatment: case report.

    A woman initially aged 25 was treated for seven years for symptomatic vaginal trichomoniasis. Throughout that period the patient received 5-nitroimidazoles at conventional and high dosages, antimicrobial agents to eliminate vaginal organisms capable of interfering with treatment, acidifying preparations, and vaccination with inactivated lactobacillus acidophilus. Despite all the regimens used, the condition remained refractory to treatment.
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ranking = 4
keywords = vaginitis
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10/12. Managing trichomonal vaginitis refractory to conventional treatment with metronidazole.

    Three patients with vulvovaginitis caused by trichomonas vaginalis, which was refractory to conventional treatment with metronidazole are described. The T vaginalis strain isolated from one patient was resistant to metronidazole (minimum inhibitory concentration (MIC) more than 100 mg/l) under aerobic conditions, although under anaerobic conditions it was as susceptible as a normal reference strain. The effect of the concomitant use of other medication and the influence of other vaginal pathogens on the efficacy of metronidazole are highlighted.
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ranking = 5
keywords = vaginitis
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