1/5. Fatal mycobacterium tuberculosis brain abscess in an immunocompetent patient.A non-hiv-infected 63-y-old woman presented seizures and coma during the course of mycobacterium tuberculosis infection. Computerized tomography scan led to the diagnosis of a large compressive brain abscess. The patient died with multiorgan failure. Systematic central nervous system investigations should be done in cases of disseminated tuberculosis.- - - - - - - - - - ranking = 1keywords = abscess (Clic here for more details about this article) |
2/5. An unusual presentation of neurotuberculosis: subdural empyema. Case report.Tuberculosis continues to be a major public health concern, especially in developing countries. Many types of neurotuberculosis have been described, but there is only one previously reported case of subdural empyema caused by tuberculous bacilli. A 1-year-old boy who had been treated for pulmonary tuberculosis was referred to the authors' institution with a diagnosis of right frontoparietal extraaxial abscess formation. Computerized tomography and magnetic resonance imaging revealed an extraaxial abscess with no evidence of calvarial infection. A craniotomy was performed to drain the pus, which was located subdurally. A polymerase chain reaction test yielded positive results, and histopathological examination revealed caseation. Antituberculous treatment was started after a diagnosis of subdural empyema with related neurotuberculosis had been made. At the end of a 12-month course of medical therapy, the patient was well with no evidence of tuberculosis.- - - - - - - - - - ranking = 0.4keywords = abscess (Clic here for more details about this article) |
3/5. Multiple tuberculous brain abscesses in an hiv-infected patient successfully treated with HAART and antituberculous treatment.Tuberculous brain abscesses (TBA) are an unusual clinical presentation of central nervous system tuberculosis occurring extremely infrequently in developed countries, and almost always in immunocompromised patients. Before the introduction of highly active antiretroviral therapy (HAART), TBA were associated with a high mortality rate in AIDS patients. We describe an hiv-infected patient presenting with multiple TBA who recovered completely with a combination of HAART and anti-tuberculous treatment.- - - - - - - - - - ranking = 1keywords = abscess (Clic here for more details about this article) |
4/5. Tuberculous brain abscess in AIDS patients: report of three cases and literature review.OBJECTIVE: Clinical description of tuberculous brain abscess in patients with acquired immunodeficiency syndrome (AIDS). methods: Clinical case report and review of the literature from January 1981 to January 2003 using the medline database. RESULTS: The authors report three cases of tuberculous brain abscess in AIDS patients and review nine similar cases. The mean age was 30 years (range: 18-56 years) with seven patients being male. Five (42%) were intravenous drug users, had prior history of extra-cerebral tuberculosis, and presented alterations on chest radiograph. tuberculin skin test was anergic in six (75%) of eight patients. Three patients of nine had a CD4 cell count higher than 200 cells/microL, and three had a CD4 cell count lower than 100 cells/microl. All but one patient had a brain computerized tomography scan with a single lesion. All patients received anti-tuberculous treatment and underwent surgical procedures. Most patients (75%) showed appropriate clinical responses. CONCLUSION: Tuberculous brain abscess must be considered in the differential diagnosis of intracranial mass in AIDS patients. A careful epidemiological, clinical and laboratory evaluation may guide a diagnostic suspicion. Surgery combined with specific anti-tuberculosis treatment seems to determine a good outcome.- - - - - - - - - - ranking = 1.4keywords = abscess (Clic here for more details about this article) |
5/5. Ocular tuberculosis in acquired immunodeficiency syndrome.PURPOSE: To present the clinical, histopathological, and molecular biologic findings in fifteen cases of ocular tuberculosis (TB) in patients with acquired immune deficiency syndrome (AIDS). DESIGN: Retrospective, observational, noncomparative case series of hiv-infected patients with ophthalmic complaints and/or with advanced disease (CD4 cell count < 200), seen between the years 1993 to 2005 at tertiary care ophthalmic and AIDS care hospitals. methods: Each patient underwent a complete ophthalmic examination and relevant laboratory and radiologic investigations and was treated accordingly. The study was carried out in this cohort to describe the ocular manifestations of TB. The main outcome measures were to describe the clinical course histopathologic and molecular biologic features of ocular lesions attributable to tuberculosis in AIDS patients in our center. RESULTS: Ocular TB was seen in 15 (1.95%) out of 766 consecutive cases of hiv/AIDS. Nineteen eyes of 15 patients were affected. Four cases (26.66%) had bilateral presentation. Presentations of ocular TB included choroidal granulomas in 10 eyes (52.63%), subretinal abscess in seven eyes (36.84%), worsening to panophthalmitis in three eyes, conjunctival tuberculosis, and panophthalmitis each in one eye (5.26%). All cases had evidence of pulmonary tuberculosis. Coexistent central nervous system (CNS) tuberculosis was seen in two cases and one case had abdominal tuberculosis. CD4 cell counts were done in 14 patients; the count ranged from 14 to 560 cells/microl--mean 160.85 cells/microl. CONCLUSIONS: Ocular TB in AIDS is relatively rare and can occur even at CD4 cell counts greater than 200 cells/microl. It can have varied presentations with severe sight-threatening complications.- - - - - - - - - - ranking = 0.2keywords = abscess (Clic here for more details about this article) |