1/22. Solitary nonreactive choroidal tuberculoma in a patient with acquired immune deficiency syndrome.PURPOSE: To report a case of a solitary, nonreactive choroidal tuberculoma in a patient with acquired immune deficiency syndrome (AIDS). METHOD: Case Report. RESULTS: A 26-year-old male patient with AIDS and systemic tuberculosis was found to have a solitary 1.5-disc-diameter elevated mass just superior and temporal to the optic disc. There was no associated inflammation, exudate, hemorrhage, or serous retinal detachment. fluorescein angiography showed late hyperfluorescence in a staining pattern. The mass quickly regressed with antituberculosis therapy. CONCLUSIONS: Choroidal tuberculoma can present with little associated inflammation or retinal change in a patient with AIDS. The clinical history and knowledge of opportunistic choroidal infections in patients with AIDS helps to make the diagnosis.- - - - - - - - - - ranking = 1keywords = tuberculoma (Clic here for more details about this article) |
2/22. Primary conjunctival tuberculoma: a case report.Conjunctival tuberculoma is very rare in modern medicine. We report a case of a 34-year-old Thai female patient presenting with multiple peculiar conjunctival nodules. Two small nodules were excised and submitted for histopathological study, which showed discrete granulomatous inflammation with caseating necrosis. The acid-fast bacilli's staining for tuberculous bacteria was positive. There was no other organ involvement of active tuberculosis. The patient was then treated with systemic anti-tuberculous regimen for 6 months. The remaining lesions disappeared within the first few months of treatment. Conjunctival tuberculoma should always be considered in cases of conjunctival nodules.- - - - - - - - - - ranking = 1keywords = tuberculoma (Clic here for more details about this article) |
3/22. Ocular scrofuloderma with unilateral proptosis.Proptosis due to an extraconal orbital abscess of tubercular origin with lacrimal gland involvement, representing ocular scrofuloderma, is a rare entity. This association has not been reported earlier in the literature. We describe a 7-year-old boy who presented with nodulo-ulcerative lesions of tubercular etiology with discharging sinuses on right side of the face and a similar lesion on the right lower eyelid along with proptosis of 4 months duration. Computerized tomography (CT) scan of the head confirmed the extraconal, intraorbital, hyperdense, homogeneously enhancing mass separated from the lateral rectus muscle and further revealed involvement of lacrimal gland along with erosion of the temporal bone. The patient showed marked improvement of his dermatological and ophthalmological lesions with anti-tubercular treatment. Subsequent ultrasound examinations of the orbit revealed regression in the size of the abscess from 10.7 mm to 5.0 mm and then complete disappearance of the abscess obviating surgical intervention.- - - - - - - - - - ranking = 7.4153934503637E-6keywords = abscess (Clic here for more details about this article) |
4/22. Orbital tuberculosis with abscess.The authors present a case of progressive unilateral proptosis caused by tuberculous osteoperiostitis of the orbital walls and sphenoid bone with extraconal orbital and extradural intracranial cold abscess formation. The patient responded well to surgical evacuation and antituberculous medical therapy.- - - - - - - - - - ranking = 1.235898908394E-5keywords = abscess (Clic here for more details about this article) |
5/22. indocyanine green angiography in ocular tuberculosis.PURPOSE: To assess indocyanine green (ICG) angiography as a method for evaluating the extent of choroidal involvement and to compare ICG angiography with fundus fluorescein angiography (FFA) in ocular tuberculosis. methods: FFA and ICG angiography were performed on two patients who had ocular tuberculosis findings during fundus examination. The patients were given topical dexamethasone phosphate, topical cyclopentolate, and oral prednisolone acetate in addition to systemic antimicrobial therapy. Both examinations were repeated after treatment. RESULTS: In one patient, two hypofluorescent lesions that corresponded to the choroidal tuberculomas were noted with ICG angiography. Only one lesion was found during ophthalmoscopic examination and FFA. After treatment, these lesions persisted, but became less hypofluorescent. In the other patient, ICG angiography showed a hypofluorescent choroidal lesion corresponding to the choroidal tuberculoma that was larger than its appearance on FFA. This lesion remained hypofluorescent in all phases of ICG angiography and became less hypofluorescent after treatment. CONCLUSIONS: ICG angiography is a useful method to determine the extent of the choroidal lesion and the stage of disease and to evaluate treatment results in tuberculosis patients.- - - - - - - - - - ranking = 0.33333333333333keywords = tuberculoma (Clic here for more details about this article) |
6/22. Simultaneous choroidal tuberculoma and epididymo-orchitis caused by mycobacterium tuberculosis.PURPOSE: To report positive polymerase chain reaction (PCR) for mycobacterium tuberculosis from the vitreous and epididymal fluid in a patient of choroidal tuberculoma and epididymitis. DESIGN: Interventional case report. methods: SETTING: Institutional setting. intervention: Vitreous and epididymal fluid tap subjected to PCR for primer IS 6110 sequence specific for M. tuberculosis. Purification of dna product and sequencing on an automated dna sequencer. Institution of antitubercular therapy. MAIN OUTCOME MEASURE: Matching of sequence with NCBI's data bank response to antitubercular therapy. RESULTS: dna products from vitreous and epidiymal fluid matched with IS 6110 sequence of M. tuberculosis. Choroidal granuloma and epididymitis responded to antitubercular therapy. CONCLUSIONS: Simultaneous choroidal tuberculoma and epididymitis resulted from an infection by M. tuberculosis, and both matched with IS 6110 sequence of M. tuberculosis.- - - - - - - - - - ranking = 1keywords = tuberculoma (Clic here for more details about this article) |
7/22. Orbital tuberculoma extending into the cranium.Orbital tuberculoma is not uncommon in the developing countries, but intracranial extension of orbital tuberculoma is extremely rare. Our case, a 14-year-old girl, presented with proptosis and progressive painless diminution of vision eventually leading to loss of vision. MRI showed a mass with peripheral enhancement of contrast, separate from the optic nerve and extending into the cranium through the optic foramen. Early decompression and chemotherapy resulted in marked visual recovery. Histopathology of the excised lesion confirmed tuberculosis. The case is reported to highlight both the rare presentation as well as remarkable visual recovery in a patient with orbital tuberculosis.- - - - - - - - - - ranking = 1keywords = tuberculoma (Clic here for more details about this article) |
8/22. Ocular tuberculosis in acquired immunodeficiency syndrome.PURPOSE: To present the clinical, histopathological, and molecular biologic findings in fifteen cases of ocular tuberculosis (TB) in patients with acquired immune deficiency syndrome (AIDS). DESIGN: Retrospective, observational, noncomparative case series of hiv-infected patients with ophthalmic complaints and/or with advanced disease (CD4 cell count < 200), seen between the years 1993 to 2005 at tertiary care ophthalmic and AIDS care hospitals. methods: Each patient underwent a complete ophthalmic examination and relevant laboratory and radiologic investigations and was treated accordingly. The study was carried out in this cohort to describe the ocular manifestations of TB. The main outcome measures were to describe the clinical course histopathologic and molecular biologic features of ocular lesions attributable to tuberculosis in AIDS patients in our center. RESULTS: Ocular TB was seen in 15 (1.95%) out of 766 consecutive cases of hiv/AIDS. Nineteen eyes of 15 patients were affected. Four cases (26.66%) had bilateral presentation. Presentations of ocular TB included choroidal granulomas in 10 eyes (52.63%), subretinal abscess in seven eyes (36.84%), worsening to panophthalmitis in three eyes, conjunctival tuberculosis, and panophthalmitis each in one eye (5.26%). All cases had evidence of pulmonary tuberculosis. Coexistent central nervous system (CNS) tuberculosis was seen in two cases and one case had abdominal tuberculosis. CD4 cell counts were done in 14 patients; the count ranged from 14 to 560 cells/microl--mean 160.85 cells/microl. CONCLUSIONS: Ocular TB in AIDS is relatively rare and can occur even at CD4 cell counts greater than 200 cells/microl. It can have varied presentations with severe sight-threatening complications.- - - - - - - - - - ranking = 2.4717978167879E-6keywords = abscess (Clic here for more details about this article) |
9/22. Tuberculosis of the lacrimal gland.A case of tuberculous dacryoadenitis with abscess formation resolving completely with anti-tuberculous chemotherapy is presented. The growth of acid-fast bacilli in culture from the pus is noteworthy.- - - - - - - - - - ranking = 2.4717978167879E-6keywords = abscess (Clic here for more details about this article) |
10/22. tuberculoma of the orbit--a case report.A case of orbital tuberculoma presenting with proptosis and gross diminution of vision in a young girl 20 years is reported. The tuberculoma disappeared within 3 months of antitubercular therapy and there was marked improvement in visual acuity. Because of its rarity in the younger age group, the case is being reported.- - - - - - - - - - ranking = 0.33333333333333keywords = tuberculoma (Clic here for more details about this article) |
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