1/7. A case of multifocal lupus vulgaris that preceded pulmonary tuberculosis in an immune compromised patient.We describe the rare case of a Japanese male with multifocal lupus vulgaris that preceded asymptomatic pulmonary tuberculosis and adult T-cell leukemia/lymphoma (ATL). He visited our hospital with multiple reddish plaques and erythema of 4-12 months duration. A skin biopsy revealed non-caseating epithelioid granulomas. mycobacterium tuberculosis was detected by polymerase chain reaction (PCR)-hybridization from a skin biopsy specimen and was also isolated from a culture of the skin biopsy sample. The result of chest roentogenography was compatible with pulmonary tuberculosis. In addition, the diagnosis of ATL was based upon the presence of atypical lymphocytes with convoluted nuclei in his peripheral blood and a positive anti-ATL antibody reaction. Cases of cutaneous tuberculosis presenting with unusual clinical features may be on the increase, accompanying the spread of tuberculosis in immunosuppressed patients, including those with ATL and acquired immunodeficiency syndrome (AIDS).- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
2/7. Pulmonary tuberculosis and cutaneous mycobacterial infection in a patient with incontinentia pigmenti.lupus vulgaris is reinfection tuberculosis of the skin and may result from direct extension, or hematogenous or lymphatic spread from a tuberculosis focus. lupus vulgaris following bacille Calmette-Guerin (BCG) vaccination is a rare entity. incontinentia pigmenti is an X-linked dominant genodermatosis in which vesicular, verrucous, and pigmented lesions are associated with various developmental defects. There is evidence of altered immunologic reactivity in some patients with incontinentia pigmenti. A 12-year-old girl hospitalized for pulmonary tuberculosis presented with bizarre-shaped brown macules following Blaschko lines on the left deltoid area, compatible with incontinentia pigmenti, which had appeared following BCG vaccination at the age of 7 years. Histopathologic examination found noncaseated granulomas in the dermis. Antituberculous treatment for pulmonary and cutaneous tuberculosis was initiated along with genetic counseling. Immunologic abnormalities have been reported in conjunction with incontinentia pigmenti. Simultaneous occurrence of pulmonary and cutaneous tuberculosis in our patient might be either coincidental or indicate derangements in the cellular immune system.- - - - - - - - - - ranking = 0.4keywords = vulgaris (Clic here for more details about this article) |
3/7. Cutaneous tuberculosis and phlyctenular keratoconjunctivitis: a forgotten association.Cutaneous tuberculosis may be associated with concurrent systemic foci in the body such as lung, lymph node, bone or CNS. Phlyctenular keratoconjunctivitis (PKC) is a manifestation of immunological response to a variety of antigens in the eye, tubercular focus (evident or occult) being the commonest in india. Reports in the existing literature have shown lungs and lymph nodes to be the predominant underlying focus associated with PKC, whereas cutaneous tuberculosis has seldom been found in this situation. We report this forgotten association in two children with cutaneous tuberculosis, one each with lupus vulgaris and scrofuloderma, who also had PKC. Interestingly, one of the cases also had simultaneous lichen scrofulosorum, which is also an immunological response to tubercular antigen and manifests in the skin, thus showing immunological manifestation in two different organ systems along with cutaneous focus of tuberculosis.- - - - - - - - - - ranking = 0.2keywords = vulgaris (Clic here for more details about this article) |
4/7. Exacerbation of pemphigus by rifampicin.Rifampicin therapy caused exacerbation of skin lesions, rising serum pemphigus antibody titres, and decreased serum betamethasone levels in a 59-year-old man with pemphigus vulgaris. Exacerbation of pemphigus was confined to the period of rifampicin therapy and seems to be best explained by the effect of rifampicin on the metabolism of betamethasone. physicians prescribing rifampicin for the treatment of tuberculosis should be aware of its potential to produce such an important adverse reaction.- - - - - - - - - - ranking = 0.2keywords = vulgaris (Clic here for more details about this article) |
5/7. lupus vulgaris of the oral mucosa. Report of 4 cases associated with asymptomatic pulmonary tuberculosis.4 cases of lupus vulgaris of the oral mucosa were found to be associated with asymptomatic pulmonary tuberculosis. The patients presented with single or multiple ulcerations of the mouth with an irregular periphery and a granular vegetative fundus. The diagnosis was established histologically and by the favorable and rapid response of the oral lesions to the antituberculosis therapy.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
6/7. lupus vulgaris in a patient with pulmonary tuberculosis.A fifty-three-year-old woman with pulmonary tuberculosis in association with lupus vulgaris is reported. Her condition had been misdiagnosed for several years; the need for early diagnosis of tuberculosis is emphasized again.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
7/7. Pulmonary tuberculosis revealed by lupus vulgaris in an immunocompetent patient.A seventy-four-year-old patient had lupus vulgaris associated with the nodular, confluent ulcerated type of pulmonary tuberculosis. The diagnosis had been missed on several occasions. The presence of cutaneous tuberculosis in developed countries is emphasized again. It is also stressed that chronic dermatosis of unknown nature in an immunocompetent patient may have a tubercular origin. Complete resolution of the disease was achieved after almost two years of anti-tubercular therapy.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |