1/10. Epidemic typhus imported from algeria.We report epidemic typhus in a French patient returning from algeria. The diagnosis was confirmed by serologic testing and the isolation of rickettsia prowazekii in blood. Initially the patient was thought to have typhoid fever. Because body lice are prevalent in industrialized regions, the introduction of typhus to pediculosis-endemic areas poses a serious public health risk.- - - - - - - - - - ranking = 1keywords = epidemic (Clic here for more details about this article) |
2/10. Epidemic typhus meningitis in the southwestern united states.A patient residing in new mexico had murine typhus diagnosed. A novel molecular assay was performed at the Centers for disease Control and Prevention, and rickettsia prowazekii, the agent of epidemic typhus, was found, rather than R. typhi. To our knowledge, this is the first reported case of epidemic typhus confirmed by means of polymerase chain reaction--based testing of cerebrospinal fluid, and it introduces a novel assay for the molecular diagnosis of both epidemic and murine typhus.- - - - - - - - - - ranking = 3keywords = epidemic (Clic here for more details about this article) |
3/10. Reemerging threat of epidemic typhus in algeria.We report a case of epidemic typhus in a patient from the Batna region of algeria, who presented with generalized febrile exanthema. The clinical diagnosis was confirmed by serological cross-adsorption followed by Western blotting. Our report emphasizes the threat of epidemic typhus in the highlands of algeria.- - - - - - - - - - ranking = 6keywords = epidemic (Clic here for more details about this article) |
4/10. Autochthonous epidemic typhus associated with bartonella quintana bacteremia in a homeless person.trench fever, a louse-borne disease caused by bartonella quintana, is reemerging in homeless persons. Epidemic typhus is another life-threatening louse-borne disease caused by rickettsia prowazekii and known to occur in conditions of war, famine, refugee camps, cold weather, poverty, or lapses in public health. We report the first case of seroconversion to R. prowazekii in a homeless person of Marseilles, france. This was associated with B. quintana bacteremia. Although no outbreaks of typhus have been notified yet in the homeless population, this disease is likely to reemerge in such situation.- - - - - - - - - - ranking = 4keywords = epidemic (Clic here for more details about this article) |
5/10. diagnosis of acute typhus infection using the polymerase chain reaction.The first use of the polymerase chain reaction (PCR) for the diagnosis of an acute rickettsial infection is described. A primer pair derived from the 17-kDa antigen sequence of rickettsia rickettsii gave specific amplification of a 434-base pair dna fragment from the genome of rocky mountain spotted fever and endemic and epidemic typhus. The assay could detect as few as 30 rickettsiae. Detection of PCR-amplified dna with a nonradioactive dna probe confirmed an acute infection with rickettsia prowazekii.- - - - - - - - - - ranking = 1keywords = epidemic (Clic here for more details about this article) |
6/10. Cardiovascular and pulmonary complications of epidemic typhus.A case of typhus fever associated with cardiac and pulmonary complications is reported. The patient was a 24-year-old Egyptian female with characteristic clinical presentation of rickettsial infection, though no rash was present throughout the course of the disease. We could not find a report of such complications in the English medical literature.- - - - - - - - - - ranking = 4keywords = epidemic (Clic here for more details about this article) |
7/10. epidemiology and ecology of rickettsial diseases in the People's Republic of china.Since 1949, information on rickettsial diseases in the People's Republic of china has been virtually nonexistent in the West. This is the first comprehensive review of the ecology and epidemiology of Chinese rickettsial diseases to be published outside the People's Republic. At least five rickettsioses exist in china: scrub typhus, murine typhus, epidemic typhus, q fever, and one or more spotted fever-group (SFG) rickettsioses. Although epidemic typhus has been controlled and scrub typhus has abated in many areas, murine typhus, q fever, and SFG rickettsiosis are important public health problems. Serologic surveys indicate high prevalences of antibodies to coxiella burnetii, Rickettsia tsutsugamushi, and SFG rickettsiae in some regions; these rickettsiae have been isolated from humans, arthropods, and animals. doxycycline has emerged as the best treatment for murine typhus, epidemic typhus, and scrub typhus. china offers both opportunities and challenges for the investigation and alleviation of the problems of rickettsial diseases.- - - - - - - - - - ranking = 3keywords = epidemic (Clic here for more details about this article) |
8/10. Evidence of rickettsia prowazekii infections in the United States.From January 1976 through January 1979 serum specimens from 1,575 individuals were received at the Center for disease Control and tested for antibodies to rickettsiae. Of these, sera from eight persons gave serological results indicative of recent infections with epidemic typhus rickettsiae (rickettsia prowazekii). Five of the persons were from georgia, and one each was from tennessee, pennsylvania and massachusetts. The illnesses occurred during the winter, chiefly in persons living in a rural environment. The clinical picture was compatible with louse-borne epidemic typhus. There was no apparent contact with human body or head lice, and no cases occurred in patient contacts, indicating that infection was not associated with the classic man-louse-man cycle of epidemic typhus. Two of the eight patients had contact with flying squirrels suggesting that they became infected from this known extrahuman reservoir of R. prowazekii.- - - - - - - - - - ranking = 3keywords = epidemic (Clic here for more details about this article) |
9/10. Epidemic typhus in the United States associated with flying squirrels.Between July 1977 and January 1980, seven cases of sporadic, nonepidemic "epidemic" typhus (rickettsia prowazekii) were discovered in Virginia, west virginia, and north carolina. The reservoir seemed to be the southern flying squirrel (Glaucomys volans), an animal indigenous to the eastern United States; however, the vector or mode of acquisition was not evident. diagnosis was established principally through complement fixation, indirect immunofluorescence, and toxin neutralization tests. patients' ages were 11 to 81 years. Most were white women. Six had abrupt onset of illness. Headaches, fever, myalgias, and exanthems were among the presenting complaints. The disease seemed milder than classic louse-born epidemic typhus, but in some instances, it was life-threatening. All patients responded to tetracycline or chloramphenicol. This entity probably is more common than reported, is difficult to recognize, and is produced by an organism seemingly identical to that producing louse-born epidemic typhus.- - - - - - - - - - ranking = 4keywords = epidemic (Clic here for more details about this article) |
10/10. Epidemic typhus fever and hearing loss: a histological study (Hallpike collection of temporal bone sections).hearing loss as a frequent complication of louse-borne epidemic typhus fever has been well documented in the reports of ENT specialists serving in both the Allied and the German armies in the last war. The present paper describes the characteristic histopathological features as noted in sections of the temporal bones from five British soldiers who died in 1944 of typhus fever during the last war in Eastern asia. The VIIIth nerve showed multiple 'typhus nodules' and there was extensive interstitial neuritis of the VIIIth nerve and demyelination of the nerve fibres. There were also widely scattered aggregations of mononuclear cells in the inner ear. This unique study was based on the Hallpike collection of temporal bone sections.- - - - - - - - - - ranking = 1keywords = epidemic (Clic here for more details about this article) |
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