1/40. Urachal carcinoma with metastasis to the maxilla: the first reported case.A case is reported for the first time of a urachal carcinoma with metastasis to the maxilla. The patient presented with a hard swelling along the left upper jaw in the region of 24-27. At the time of onset there were skin changes and signs of metastasis to the brain. The patient died 13 months after the onset of symptoms.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
2/40. Multiple primary malignant neoplasms: case report and a comprehensive review of the literature.A case is presented of an elderly patient with synchronous ureteral/bladder/urethral transitional cell carcinoma and prostatic adenocarcinoma. In a subsequent review of 1,104,269 cancer patients in the literature, the reported prevalence of multiple primary malignant neoplasms (MPMN) varies between 0.734% and 11.7%. It appears that MPMN might occur more frequently than can be explained on the basis of random chance. As expected, the incidence of developing MPMN is noted to rise with increasing age. In addition, the preponderance of men with MPMN is caused primarily by the high frequency of prostatic cancer. Current studies and research need to address the potential of older cancer patients being at higher risk of second primaries.- - - - - - - - - - ranking = 0.4keywords = carcinoma (Clic here for more details about this article) |
3/40. Case report: metastatic transitional cell carcinoma presenting in a urinoma.We describe a case of transitional cell carcinoma (TCC) metastasising into a urinoma cavity in a patient where the primary tumour arose at the ipsilateral ureterovesical junction. Seeding of transitional cell carcinoma into contiguous structures following surgical intervention has been reported, but to our knowledge, this is the first report of spread into a distant urinoma.- - - - - - - - - - ranking = 1.2keywords = carcinoma (Clic here for more details about this article) |
4/40. Is cytology required for a hematuria evaluation?PURPOSE: The value of urine cytology in evaluating patients with hematuria remains controversial. The American Urological association Best Practice policy on Asymptomatic Microscopic hematuria recommends cytology only in patients with risk factors for transitional cell carcinoma (TCC). This study evaluated how often urine cytology yielded supportive or unique information that led to the diagnosis of transitional cell carcinoma, the cost of that information and whether it would have been obtained using the current best practice policy. MATERIALS AND methods: Between March 1976 and June 1985, 1,000 sequential patients with 1 episode of gross hematuria or microscopic hematuria, defined as greater than 3 red blood cells per high power field on 2 of 3 properly collected urinalyses, were evaluated according to a standard protocol in a closed panel health care system in the state of hawaii. These records were reviewed to determine if urine cytology yielded supportive or unique information that led to the diagnosis of TCC. RESULTS: In 4 patients positive urine cytology was the sole finding supporting a TCC diagnosis. urine cytology had a sensitivity of 55% and a specificity of 99.3%. The cost of a cytology result that yielded unique information was 8,367 US dollars using the 2002 medicare reimbursement schedule. CONCLUSIONS: urine cytology can have an important role in the evaluation of hematuria. The current American Urological Society Best Practice policy using risk factors to select patients for urine cytology would have captured the 4 patients for whom cytology was the key to diagnosis. urine cytology was comparable to excretory urography, creatinine and cystoscopy in terms of cost analysis.- - - - - - - - - - ranking = 0.4keywords = carcinoma (Clic here for more details about this article) |
5/40. The nested variant of transitional cell carcinoma: a neoplasm resembling proliferation of Brunn's nests.This report describes four cases in which a malignant transitional cell neoplasm initially manifested as small nests and abortive tubules infiltrating the lamina propria. Many of the tumor cells were only slightly atypical but careful examination revealed at least some significantly anaplastic cells in every case, the degree of cellular atypia tending to parallel the depth of invasion. Despite the initial impression of a benign lesion resembling a proliferation of Brunn's nests, these carcinomas tended to be persistent and aggressive.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
6/40. Retroperitoneal lymph node dissection in patients with interaortocaval lymph node metastases of transitional cell carcinoma of the urinary tract.Three patients suffered from renal pelvic, ureteral and bladder cancers that were treated with both standard surgical treatments and two adjuvant cycles of cisplatin-based combination chemotherapy. Metastases of interaortocaval lymph nodes were detected in all patients between 9 and 33 months from the surgery for primary lesions. All patients received three cycles of cisplatin-based combination chemotherapy and retroperitoneal lymph node dissection (RPLND). The chemotherapy achieved partial response (62-98%). Two patients with viable cancer cells died with hepatic metastases; the first 15 months and the second 25 months from the date of diagnosis of distant lymph node metastasis. The third patient, who had no viable cancer cells, remains alive and disease-free 36 months later. Therefore, RPLND after chemotherapy provides prognostic information that helps to define patients who might benefit from additional systemic chemotherapy.- - - - - - - - - - ranking = 0.8keywords = carcinoma (Clic here for more details about this article) |
7/40. Urinary exenteration on a renal transplant recipient with multifocal urothelial cancers and prostatic adenocarcinoma.The two cancers after renal transplantation (RTx) are transitional cell carcinoma (TCC) and hepatoma reported in taiwan most frequently, versus lymphproliferative diseases and skin cancers in the Western literature. Herein, we present a 49-year-old man with spinal cord injury and end-stage renal disease who developed multifocal TCC in the urologic tract and incidental detection of prostatic adenocarcinoma 15 months after a cadaveric RTx. En bloc complete native urinary tract excision and ileal conduit urinary diversion were performed smoothly. After 2-year follow up, there was no evidence of tumor recurrence, and graft function remained stable, with minimal hydronephrosis. Transplant physicians should carefully monitor any signs of urinary cancers, especially in renal transplant recipients with history of analgesics. Also, aggressive surgical treatment is recommended for these patients to prolong survival.- - - - - - - - - - ranking = 1.2keywords = carcinoma (Clic here for more details about this article) |
8/40. Upper urinary tract metastases from adenocarcinoma of the colon.An unusual presentation of colorectal metastasis to the upper urinary tract is reported. The metastasis manifested as a filling defect seen during antegrade pyelography. Cytologic evaluation of aspirated material demonstrated metastatic colonic adenocarcinoma. A dilated collecting system may be caused by intraluminal material including tumor and blood clots. Whenever fixed filling defects are encountered, urine cytology should be sent even in the absence of renal parenchymal involvement by tumor. The cytological evaluation may allow for prompt diagnosis and treatment.- - - - - - - - - - ranking = 1keywords = carcinoma (Clic here for more details about this article) |
9/40. Four primary tumors of lung, bladder, prostate, and breast in a male patient.We present a very rare case of quadruple cancers in a 65-year-old male patient. It is a case of both synchronous and metachronous primary malignant neoplasms occurring in four different organs. Immunohistochemical stains showed tumor cell nuclei to be negative for p53 over-expression. To our knowledge, this is the first documented case with this combination of primary tumors. The tumors included an adenosquamous cell carcinoma of the lung, transitional cell carcinoma of the urinary bladder, and adenocarcinomas of the prostate and the breast. We also review the medical literature for the possible causes of multiple primary malignant neoplasms.- - - - - - - - - - ranking = 0.6keywords = carcinoma (Clic here for more details about this article) |
10/40. Sudden late onset of gross hematuria in a previous renal transplant recipient 3 months after transplant nephrectomy.Causes of gross hematuria in a patient with end-stage renal disease are limited compared with those in patients with normal renal function. Given the increased likelihood of patients with end-stage renal disease developing renal cell carcinoma, the workup focuses on a careful evaluation of the collecting system. The workup for gross hematuria in a renal transplant recipient is similar; however, the focus shifts toward a more thorough evaluation of the transplanted kidney and bladder because immunosuppression increases the overall risk for malignancy. An immunosuppressed patient also is at risk for infectious processes in the transplanted kidney manifesting as gross hematuria. Concerns for chronic rejection also should be investigated, although microscopic hematuria is more common in this scenario. If this is unrevealing, then close scrutiny of the native kidneys for possible sources of bleeding is warranted. We present an interesting and unusual cause of painless gross hematuria in a patient with end-stage renal disease and transplant nephrectomy 3 months before the onset of bleeding.- - - - - - - - - - ranking = 0.2keywords = carcinoma (Clic here for more details about this article) |
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