1/16. Uterine cervical adenofibroma associated with Turner's syndrome in a young woman.A 32-year-old woman with Turner's syndrome complained of abnormal genital bleeding, which was diagnosed as a delivered myoma. Vaginal myomectomy was performed, and the tumor was histopathologically diagnosed as an adenofibroma of the uterine corpus. As these are extremely rare, we report this case with a review of some of the literature.- - - - - - - - - - ranking = 1keywords = adenofibroma (Clic here for more details about this article) |
2/16. A menopausal woman with mullerian agenesis, a leiomyoma, an inguinal hernia, and cystadenofibromas.BACKGROUND: Mullerian agenesis, the second most common cause of primary amenorrhea, affects 1 in 4,000 to 10,000 women. Although the majority of these women have complete absence of the uterus, a small percentage can have a rudimentary uterus. CASE: A menopausal nulligravida with known mullerian agenesis developed a large pelvic mass and an inguinal hernia. The patient underwent an exploratory laparotomy, which revealed a large leiomyoma growing from a small rudimentary uterus, an indirect inguinal hernia, and bilateral benign serous cystadenofibroma. CONCLUSION: women with mullerian agenesis and rudimentary uteri can develop gynecologic pathology similar to women with normal genital tracts.- - - - - - - - - - ranking = 1keywords = adenofibroma (Clic here for more details about this article) |
3/16. Primary leiomyoma of the ovary co-existing with serous cystadenofibroma.A 48-year-old woman with a 14 cm left ovarian mass had total abdominal hysterectomy and bilateral salpingo-oophorectomy. On cut section the tumor had a solid and a cystic component. There was a 2.5 cm nodule attached to the cyst wall. Sections taken from the solid component revealed a tumor composed of interlacing bundles of fusiform cells, resembling a leiomyoma. Smooth muscle actin positivity confirmed the diagnosis. Sections taken from the nodule in the cystic part revealed an adenofibroma. There was an SMA positive area in the cyst wall which we think is the possible origin of the leiomyoma. As far as we know, this is the first case of a co-existing leiomyoma and serous cystadenofibroma in the ovary, and we think it will broaden the histological spectrum of primary ovarian leiomyomas.- - - - - - - - - - ranking = 1.2keywords = adenofibroma (Clic here for more details about this article) |
4/16. Papillary adenofibroma of the uterus. Report of a case involved by adenocarcinoma and review of the literature.An unusual case of uterine papillary adenofibroma involved by an invasive well-differentiated adenocarcinoma is reported. The diagnosis was established using a hysterectomy specimen from a 68-year-old woman who was initially examined for abdominal pain and vaginal bleeding. The tumor was a broad-based polypoid mass composed of papillary projections into clefts and cysts. These papillations were covered by a variety of epithelial types and focally involved by an infiltrating adenocarcinoma. The stroma was fibrous and collagenized with variable numbers of benign fibroblasts. The papillary adenofibroma is considered to be a benign mixed tumor of Mullerian origin. Fifteen other cases of uterine adenofibroma have been reported in the literature and only one of these was focally involved by an adenocarcinoma. The clinical and histologic features of this rare disease are reviewed.- - - - - - - - - - ranking = 1.4keywords = adenofibroma (Clic here for more details about this article) |
5/16. adenomyoma: a precursor of extrauterine Mullerian adenosarcoma?One patient had an extrauterine pelvic Mullerian adenosarcoma that recurred on multiple occasions and was originally diagnosed as a benign lesion. Caution is needed in the initial interpretatrion of such lesions as "adenofibromas." We have compared this lesion with a benign adenomyoma of the uterus from a second patient and suggest that such benign neoplasms serve as precursors for Mullerian adenosarcoma in some cases. light and electron microscopic observations in the first case as well as data from the literature support this hypothesis.- - - - - - - - - - ranking = 0.2keywords = adenofibroma (Clic here for more details about this article) |
6/16. Mullerian adenofibroma of the uterus with invasion of myometrium and pelvic veins.Two cases of mullerian adenofibroma of the uterus with unusual features are described. The tumors were encountered in patients 51 and 70 years of age who presented with abdominal pain and postmenopausal bleeding, respectively; both patients were found to have a pelvic mass. Intraoperative findings included an enlarged uterus in each case, and in one of them, uterine rupture and worm-like plugs of tumor within veins of both broad ligaments. Examination of the hysterectomy specimens revealed polypoid endometrial tumors that deeply invaded the myometrium. On histologic examination, both tumors were composed of an intimate admixture of benign endometrial-type glands and a moderately cellular stroma containing fibroblasts with benign nuclear features and very low mitotic activity (less than one mitotic figure per 10 high-power fields). Both tumors infiltrated the myometrium almost to the serosa, and one of them grew within the lumens of large myometrial veins. The patients had uneventful postoperative follow-up periods of greater than 3 years. This report indicates that rare, otherwise typical uterine adenofibromas can exhibit invasive properties and may have a malignant potential.- - - - - - - - - - ranking = 1.2keywords = adenofibroma (Clic here for more details about this article) |
7/16. Adenofibroma of the uterus: multiple recurrences following wide local excision.The uterine adenofibroma is a form of mixed mesodermal tumor in which both epithelial and stromal components are benign. A case is presented in which a patient with this lesion was treated with excision of the tumor rather than hysterectomy. Two years later, she developed a recurrence of the lesion, which was again treated with wide local excision. A hysterectomy was done 9 months later, and a polypoid lesion was noted in the fundus of the uterus which on histologic examination was thought to be potentially either an adenofibroma precursor or a maturation of the previous cellular adenofibroma. Since uterine adenofibroma usually occurs in older patients, the standard treatment has been hysterectomy. Because of this patient's age, she was initially treated with a more conservative approach. However, despite the fact that the uterine adenofibroma is a benign lesion, it has an obvious potential to recur when treated conservatively.- - - - - - - - - - ranking = 1keywords = adenofibroma (Clic here for more details about this article) |
8/16. Atypical polypoid adenomyoma of the uterus. An immunohistochemical study of a case.We studied one case of atypical polypoid adenomyoma of the uerus immunohistochemically using antisera against keratins, vinentin, S-100 protein, desmin and actin. The stromal cells were reactive with anti-actin and antidesmin antibodies suggesting a muscular phenotype and confirming previous ultrastructural data. Immunohistochemical investigations have proved to be useful in differential diagnosis of APA with invasive adenocarcinoma, adenosarcoma and adenofibroma of the endometrium.- - - - - - - - - - ranking = 0.2keywords = adenofibroma (Clic here for more details about this article) |
9/16. Invasive ovarian endometrioid adenofibroma with omental implants and collision with endometrial adenocarcinoma.A case of endometrioid adenofibroma of the ovary with omental implants, extensive invasion into the wall of the ipsilateral fallopian tube, and collision with an endometrial papillary adenocarcinoma is reported. Fewer than 35 malignant cystadenofibromas and adenofibromas have been reported. In all of these cases, the malignant epithelium was believed to originate from preexisting benign tumors. This case is unusual in that it demonstrated no malignant epithelium beyond that of a borderline tumor, but met the criteria of malignancy because of its invasiveness and metastasis.- - - - - - - - - - ranking = 1.4keywords = adenofibroma (Clic here for more details about this article) |
10/16. Ovarian endometrioid carcinoma with an adenofibromatous pattern.We report the case of a 66-year-old postmenopausal woman who underwent unilateral oophorectomy for an ovarian endometrioid carcinoma with an unusual adenofibromatous stromal reaction pattern. She is presently alive, well and without clinical evidence of tumour two years after surgery. Adenofibromatous or cystadenofibromatous reaction is a peculiar reactive ovarian stromal change most probably induced by the invading neoplastic epithelial cells. No definite conclusions have been reached regarding the prognostic significance of this special stromal tissue reaction in cases of endometrioid carcinoma of the ovary.- - - - - - - - - - ranking = 1.2keywords = adenofibroma (Clic here for more details about this article) |
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