1/2. Anaesthetic considerations in Castleman's disease.Castleman's disease is a lymphoreticular disorder, often localized and clinically silent. Systemic manifestations may occur. Castleman's disease may be associated with pathologies such as poems syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes), AIDS, amyloidosis, pemphigus vulgaris, and other types of cancer such as lymphoma and Kaposi's sarcoma. Careful preoperative evaluation is required to determine whether associated mediastinal or spinal canal masses or haematological disorders are present. The significance of these pathologies for anaesthetic management is discussed. We present the case of a 27-year-old female patient with Castleman's disease (hyaline-vascular variant) requiring vaginal reconstruction due to recurrent sores and synechiae.- - - - - - - - - - ranking = 1keywords = vulgaris (Clic here for more details about this article) |
2/2. pemphigus vulgaris and pregnancy: risk factors and recommendations.pemphigus vulgaris during pregnancy is exceedingly rare; only 15 cases with immunopathologic confirmation have been reported. In the four cases associated with fetal mortality the mother's disease was active and required high doses of corticosteroids and adjuvant therapy with azathioprine or dapsone for control. A pregnant woman with limited disease is described. At the time of delivery her pemphigus vulgaris antibody titer was 1:640. A full-term, healthy male infant was completely free of skin lesions after a spontaneous vaginal delivery.- - - - - - - - - - ranking = 6keywords = vulgaris (Clic here for more details about this article) |