1/1302. Peripheral ulcerative keratitis--an extracutaneous neutrophilic disorder: report of a patient with rheumatoid arthritis, pustular vasculitis, pyoderma gangrenosum, and Sweet's syndrome with an excellent response to cyclosporine therapy.The term peripheral ulcerative keratitis represents a spectrum of inflammatory diseases, characterized by cellular infiltration, corneal thinning, and ulceration. Neutrophilic dermatoses are rarely associated with peripheral ulcerative keratitis. To date, peripheral ulcerative keratitis has only been reported in patients with pyoderma gangrenosum. Separate episodes of pyoderma gangrenosum, Sweet's syndrome, and pustular vasculitis developed in a 60-year-old patient with rheumatoid arthritis over an 8-year period. Over the past 2 years, 3 episodes of peripheral ulcerative keratitis occurred. cyclosporine (4 mg/kg/d) treatment was started on confirmation of pyoderma gangrenosum. Over the ensuing 2 years, it became evident that the activity of her ocular and skin diseases, as well as her arthritis, paralleled the administration or cessation of cyclosporine therapy. Dermatologists should be aware of the association of Sweet's syndrome, pyoderma gangrenosum, and pustular vasculitis with peripheral ulcerative keratitis. This rare ocular manifestation and the serious sequelae when left untreated make recognition crucial. cyclosporine proved to be a very effective treatment for all of our patient's diseases.- - - - - - - - - - ranking = 1keywords = vasculitis (Clic here for more details about this article) |
2/1302. Systemic candidiasis with candida vasculitis due to candida kruzei in a patient with acute myeloid leukaemia.candida kruzei-related systemic infections are increasing in frequency, particularly in patients receiving prophylaxis with antifungal triazoles. A Caucasian male with newly diagnosed acute myeloid leukaemia (AML M1) developed severe and persistent fever associated with a micropustular eruption scattered over the trunk and limbs during induction chemotherapy. Blood cultures grew candida kruzei, and biopsies of the skin lesions revealed a candida vasculitis. He responded to high doses of liposomal amphotericin b and was discharged well from hospital.- - - - - - - - - - ranking = 0.83333333333333keywords = vasculitis (Clic here for more details about this article) |
3/1302. Vasculitis confined to the peripheral nerve and skin: a variant of non-systemic vasculitic neuropathy.We describe a patient presenting with vasculitic neuropathy associated with cutaneous vasculitis in the absence of other clinical or laboratory evidence of the underlying systemic vasculitis, and showing a favourable prognosis. Although the early proposed criteria for the diagnosis of non-systemic vasculitic neuropathy (NSVN) exclude the involvement of extraneural tissues, the condition observed in our patient might represent a variant of NSVN, with the vasculitis confined to the small vessels in both the peripheral nerve and the skin.- - - - - - - - - - ranking = 0.5keywords = vasculitis (Clic here for more details about this article) |
4/1302. A Japanese case of dengue fever with lymphocytic vasculitis: diagnosis by polymerase chain reaction.A 37-year-old Japanese male was admitted to Nagasaki University Hospital with abrupt onset of biphasic fever, general malaise and myalgia 9 days after coming back to japan from Manila. He developed a rubella like erythematous rash 3 days after admission and purpuric eruption one week after admission. A biopsied specimen from the purpura revealed lymphocytic vasculitis with T cell dominance and without immunoglobulin or complement deposition around the blood vessels. RT-PCR analysis on peripheral blood mononuclear cells using dengue virus specific primers confirmed the diagnosis of type 3 dengue fever. PCR analysis using virus specific primers is a rapid and valuable method for making a correct diagnosis of dengue fever.- - - - - - - - - - ranking = 0.83333333333333keywords = vasculitis (Clic here for more details about this article) |
5/1302. Systemic adverse effect of antithyroid drugs.Antithyroid drugs adverse effects are varied and rare. Autoimmune disorders (vasculitis, lupus erythematosus, polyarthritis...) are unusual and serious complications of antithyroid drugs. Since 1945, fewer than 100 cases of systemic manifestations related to antithyroid drugs have been reported in the literature, most frequently with propylthiouracil. The outcome is usually good after drug discontinuation, but some fatal cases have been reported. Because possible cross-sensitivity with other antithyroid drugs, the appropriate treatment for hyperthyroidism relapse if a patient has had an antithyroid drug adverse reaction, should be 131I-iodine or surgery. We report four new cases of systemic manifestations during propylthiouracil therapy.- - - - - - - - - - ranking = 0.16666666666667keywords = vasculitis (Clic here for more details about this article) |
6/1302. CNS pseudovasculitis in a patient with pheochromocytoma.The authors report a patient with angiographic findings resembling CNS vasculitis (CNS pseudovasculitis) who was found to have a pheochromocytoma. The angiographic changes resolved after surgical resection of the pheochromocytoma. pheochromocytoma should be included in the differential diagnosis of angiographic findings suggestive of CNS vasculitis.- - - - - - - - - - ranking = 1.1666666666667keywords = vasculitis (Clic here for more details about this article) |
7/1302. Successful treatment of hiv-related vasculitis with peripheral neuropathy with short-term steroids followed by the association of zidovudine and plasmapheresis.OBJECTIVE--treatment of hiv-related vasculitis, avoiding prolonged immunosuppressive therapy. DESIGN--prospective pilot study of hiv-related neurological vasculitis. patients--two hiv-infected patients with histologically proven vasculitis. INTERVENTION--short-term corticosteroid followed by zidovudine combined with plasmapheresis. MAIN OUTCOME MEASURES--clinical, biological, immunological and electromyographic evaluation. RESULTS--complete neurological recovery. CONCLUSION--excellent tolerance and efficacy of combined zidovudine and plasmapheresis therapy in peripheral neurological hiv-related vasculitis.- - - - - - - - - - ranking = 1.3333333333333keywords = vasculitis (Clic here for more details about this article) |
8/1302. Vasculitic polyradiculopathy in systemic lupus erythematosus.A 22 year old woman with recently diagnosed systemic lupus erythematosus presented with subacute progressive areflexic paraparesis, electrophysiologically identified as a pure axonal polyradiculopathy. sural nerve biopsy disclosed necrotising vasculitis. A striking radiological feature was marked enhancement of the cauda equina with gadolinium.- - - - - - - - - - ranking = 0.16666666666667keywords = vasculitis (Clic here for more details about this article) |
9/1302. Livedoid vasculitis: a manifestation of the antiphospholipid syndrome?Livedoid vasculitis, otherwise known as segmental hyalinizing vasculitis or livedo reticularis with summer ulceration, is a chronic disease with lesions affecting the feet and lower legs. Early lesions show petechiae, but characteristic features are recurrent, bizarrely shaped ulcers that heal to leave hyperpigmentation and atrophie blanche. The aetiology of the disorder is unknown, but the histology shows fibrin deposition within both the wall and lumen of affected vessels. The absence of a sufficient perivascular infiltrate or leucocytoclasia argues against a vasculitis, being more in keeping with a thrombo-occlusive process. Four patients with livedoid vasculitis with ulceration are described, all of whom had associated raised anticardiolipin antibodies but no other evidence of systemic disease. We suggest that livedoid vasculitis may be a manifestation of the antiphospholipid syndrome and recommend that all patients are screened for this. We also discuss treatment options for this often resistant condition.- - - - - - - - - - ranking = 1.5keywords = vasculitis (Clic here for more details about this article) |
10/1302. Efficacy of filtration leukocytapheresis on rheumatoid arthritis with vasculitis.The present study was designed to determine the efficacy of filtration leukocytapheresis (LCAP) in the treatment of rheumatoid arthritis (RA) with vasculitis. Nine RA patients with vasculitis were studied by the Malignant RA Collaborative Group formed by 8 clinical centers. A total of 7 filtration LCAP procedures using the Cellsorba column (Asahi Medical Co., Ltd., tokyo, japan) were performed with 1 week intervals between treatments. During each apheresis procedure, 3,000 ml of blood was filtered and returned to the patient at a flow rate of 50 ml/min for 60 min. In addition to the amelioration of arthritis, the improvement of extraarticular symptoms associated with rheumatoid vasculitis such as polyneuritis, skin ulcers, digital gangrene and rheumatoid nodules was obtained. In contrast, no improvement was observed in interstitial pneumonia or lung fibrosis. LCAP could be an optional modality for the treatment of RA with vasculitis.- - - - - - - - - - ranking = 1.3333333333333keywords = vasculitis (Clic here for more details about this article) |
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