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1/6. A human case of encephalitis associated with vesicular stomatitis virus (indiana serotype) infection.

    This paper describes a case of severe encephalitis in a 3-year-old Panamanian boy infected with the indiana serotype of vesicular stomatitis virus. The virus was recovered from the child's throat on the fifth day of illness and a rise in neutralizing antibody titer was demonstrated in paired serum specimens. This is the second report of childhood encephalitis associated with vesicular stomatitis virus infection. These suggest that infection with vesicular stomatitis viruses may cause severe disease. Human infection with vesicular stomatitis viruses is common throughout the tropical americas.
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ranking = 1
keywords = throat
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2/6. Diagnosis of human immunodeficiency virus infection in seronegative homosexuals presenting with an acute viral syndrome.

    early diagnosis of acute human immunodeficiency virus (hiv) infection is difficult because patients may be seronegative for hiv at the time of presentation. We have used a serum hiv antigen (hiv-Ag) enzyme immunoassay (EIA) to diagnose acute hiv infection in four high-risk patients. The clinical syndrome in these four patients was characterized by fever (four), rash (three), myalgias-arthralgias (three), and pharyngitis (two). All patients had spontaneous resolution of their symptoms within eight to 12 days. serum hiv antibody, as measured by a commercially available screening EIA and by Western blot analysis, was negative in all patients at time of presentation and all seroconverted on subsequent testing. Human immunodeficiency virus was isolated from two of two patients during the acute illness. Initial serum samples from all four patients were positive for hiv-Ag. serum samples of three of four patients became negative for hiv-Ag and positive for hiv antibody. These data suggest that serum hiv-Ag detection by EIA may be useful in the diagnosis of the acute syndrome caused by hiv infection.
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ranking = 23.926846929448
keywords = pharyngitis
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3/6. fusobacterium necrophorum septicemia without a primary focus.

    We have presented a case of fusobacterium necrophorum septicemia, an uncommon infection whose early course may be typified by vague diffuse symptoms or a seemingly benign upper respiratory tract inflammation mimicking acute viral syndromes or viral pharyngitis. The septicemia is most commonly, but not always preceded by an obvious oropharyngeal focus.
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ranking = 23.926846929448
keywords = pharyngitis
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4/6. streptobacillus moniliformis isolated from blood in four cases of Haverhill fever.

    During February, 1983, an outbreak of an unusual febrile illness occurred in over 130 children attending a boarding school in Chelmsford, Essex. The clinical features included fever, an erythematous rash that was most prominent on the hands and feet, arthralgia, and the subsequent development of a sore throat. The nature and distribution of the rash varied considerably between patients and at different stages of illness. At first a viral aetiology was regarded as most likely. When streptobacillus moniliformis was later isolated from the blood of 4 of the patients with moderately severe illnesses it became apparent that an outbreak of Haverhill fever had occurred at this school. The most probable source of the outbreak was raw milk, since all 4 patients had consumed raw milk at the school shortly before the onset of symptoms and there was no evidence of person-to-person spread of infection.
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ranking = 36.906168091894
keywords = sore throat, throat
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5/6. STAR complexes: febrile illnesses associated with sore throat, arthritis, and rash.

    Between January 1990 and February 1991 we evaluated the cases of 20 patients for a symptom complex consisting of Sore throat, elevated temperature, migratory arthritis, and a pruritic urticarial Rash (STAR). The patients ranged in age from 3 1/2 to 48 years; most were from central texas. Duration of illness varied from 2 weeks to longer than 1 year. Results of laboratory studies included the following abnormal findings: elevated erythrocyte sedimentation rate, leukocytosis, anemia, and thrombocytosis. Eleven of 18 (61%) patients had low antinuclear antibody titers. HLA-A2 was noted in 8 of 10 (80%) of those tested. Test results were positive in eight cases for IgM antibodies to parvovirus and in six cases for IgM antibodies to rubella, suggesting that these entities may represent an underdiagnosed cause of STAR complex. In six cases no specific cause of disease was found; these cases may be attributable to other infectious agent(s) yet to be identified. Here we present a description of the cases, a discussion of the differential diagnosis, and an evaluation of STAR complex.
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ranking = 148.62467236758
keywords = sore throat, throat
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6/6. Differential diagnosis of common causes of pediatric pharyngitis.

    pharyngitis or sore throat is a common result of illness in pediatric and adolescent populations. Sore throat can signal either nonsystemic or systemic disease processes. Clinicians in ambulatory settings are often faced with deriving a differential diagnosis based on this symptom. Prompt and appropriate treatment depends on identification of the underlying causative agent or illness. This article examines common causes of sore throat in the pediatric and adolescent populations. These diagnoses are: (1) group A beta-hemolytic streptococcal pharyngitis; (2) non-group A beta-hemolytic streptococcal bacterial pharyngitis; (3) viral pharyngitis; (4) infectious mononucleosis; and (5) chronic conditions. Less common causes are also considered. Differential diagnosis is dependent on complete and accurate history, distinct physical finding, and interpretation of adjunct diagnostic tests. The value of critical data sources is essential in arriving at a differential diagnosis of pharyngitis. Once a diagnosis is established, an appropriate treatment plan can be initiated.
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ranking = 266.22711161937
keywords = sore throat, pharyngitis, throat
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