1/13. dermatitis herpetiformis and vitiligo: report of a case and review of the literature.We describe the case of a 53-year-old woman presenting papulous and papulovesicular lesions that were highly pruritic, localized mostly in the achromic areas of vitiligo and symmetrically distributed on the elbows, the buttocks, the shoulders and the neck. The histopathological examination performed on the elbow's lesional skin showed the presence of neutrophils and fibrin microabscesses at the tips of dermal papillae, with a few eosinophils, and small separations between the dermis and epidermis just over the infiltrate. The overlying epidermis was uninjured. The performed tests detected IgA anti-endomysium, anti-thyrogloblin, anti-smooth muscle and anti-microsomal fraction autoantibodies; DIF showed the presence of IgA granular deposits at the dermo-epidermal junction, prevalently at the tips of dermal papillae. This is the tenth case reported of an association between dermatitis herpetiformis and vitiligo. Although the two disorders both have immunological pathogeneses, we think that the topographic coexistence of both disorders is coincidental.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
2/13. Bullous contact dermatitis caused by self-applied crushed Paederus fuscipes for the treatment of vitiligo.Paederus dermatitis is a linear, blistering contact dermatitis caused by pederin, a potent vesicant agent that is contained in insects belonging to the genus Paederus. This form of dermatitis usually occurs accidentally in those who have contact with this insect during the summer season. We report a peculiar case of a patient developing severe chemical burnlike lesions after application to her skin of many crushed Paederus fuscipes that she collected from the soil of a riverbank in the early spring for the treatment of her vitiligo.- - - - - - - - - - ranking = 7keywords = dermatitis (Clic here for more details about this article) |
3/13. Halo dermatitis followed by the development of vitiligo associated with Sutton's nevi.Halo dermatitis (Meyerson's nevus) is an inflammatory, sometimes itchy, eczematous eruption usually encircling a preexisting melanocytic nevus that can be mistaken for malignant melanoma or Sutton's nevus. Unlike the latter, it mostly resolves spontaneously within weeks and never causes regression of the central lesion. Sutton's nevi, however, are frequently found in otherwise healthy individuals and patients suffering from vitiligo or malignant melanoma. The simultaneous appearance of Sutton's nevus and halo dermatitis has been reported before. However, the causes of both diseases remain unclear. We report a 16-year-old female who developed vitiligo and Sutton's nevi 6 months after a halo dermatitis lesion was excised. The coincidence of these disorders suggests common or similar immunological mechanisms induced by pigment cells and/or their components.- - - - - - - - - - ranking = 7keywords = dermatitis (Clic here for more details about this article) |
4/13. Present status of eyelid phototherapy. Clinical efficacy and transmittance of ultraviolet and visible radiation through human eyelids.BACKGROUND: phototherapy for the eyelid has not previously been recognized as a safe and effective treatment of photoresponsive dermatoses of the eyelid, such as atopic dermatitis, vitiligo, psoriasis, lymphomatoid papulosis, and parapsoriasis. OBJECTIVE: The purpose of this study was to demonstrate the efficacy and safety of this treatment. methods: Two cases are presented to demonstrate clinical efficacy. In addition, a retrospective eye evaluation of seven patients receiving a combined total of greater than 1300 eyelid phototherapy treatments was performed. To determine whether potentially harmful UV radiation is significantly transmitted through eyelid skin, an in vitro study was conducted to measure the percentage transmittance of ultraviolet-visible radiation through five excised eyelids. RESULTS: In the two cases presented, remarkable improvement occurred without adverse side effects, suggesting that it is possible to deliver incremental UV dosages to eyelid skin to achieve clearing of skin disease. Retrospective analysis of patients' records revealed no ocular disease from the phototherapy. in vitro eyelid examination produced data that indicated negligible quantities of UV radiation were transmitted through eyelid skin compared with the visible spectrum, in which up to 77% of the radiation was transmitted through the tissue. CONCLUSION: The combined clinical experience and transmittance data suggest that eyelid phototherapy is a safe and effective treatment in selected patients.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
5/13. Contact vitiligo following a strong patch test reaction to triglycidyl-p-aminophenol in an aircraft industry worker: case report and review of the literature.Epoxy resin systems (ERSs) are a frequent cause of occupational allergic contact dermatitis. A 50-year-old patient developed eczematous skin lesions on the back of his hands, lower arms and eye lids, 2 months after he had started working in aircraft construction. patch tests showed positive reactions at day 3 to nickel sulfate, epoxy resin based on diglycidyl ether of bisphenol F (DGEBF) and 1,4-butanediol diglycidyl ether (1,4-BDDGE). The chemical triglycidyl-p-aminophenol (TGPAP) applied at 1% and 0.1% induced the strongest ( positive) reaction. About 4 months after the patch test with TGPAP, the patient presented with 2 circular depigmented spots in the former TGPAP-patch test areas. Dermatohistopathology confirmed the diagnosis of contact vitiligo.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
6/13. vitiligo with inflammatory raised borders, associated with atopic dermatitis.A 31-year-old man had had atopic dermatitis since childhood and developed vitiligo with inflammatory raised borders 5 years prior to presentation. Immunohistochemically, CD4 T cells infiltrated predominantly in the raised border of vitiligo, while CD8 T cells were present just outside of the borders, suggesting that CD8 cells were an antecedent to the CD4 cells. Despite the presence of atopic dermatitis, the percentage of CXCR3 CD4 th1 cells increased in the patient's peripheral blood, compared with a representative atopic patient showing a high percentage of CCR4 CD4 th2 cells. This case suggests that vitiligo with inflammatory raised borders can occur even in patients with atopic dermatitis when th1 cells are activated and overcome the Th2-dominant state.- - - - - - - - - - ranking = 7keywords = dermatitis (Clic here for more details about this article) |
7/13. Two cases of nickel dermatitis showing vitiligo-like depigmentations.The authors reviewed two patients showing "vitiligo-like depigmentations" where the skin had been in close contact with a metal spectacle frame made of nickel alloy. In spite of the hypersensitivity to nickel in both patients, they showed clinical and histologic findings indicate that the formation of "vitiligo-like depigmentation" does not result from posinflammatory hypopigmentation but from chemical hypomelanosis. We could not explain the underlying mechanisms; however, the speculation that the "vitiligo-like depigmentation" may come from the direct effect of the nickel itself, prompted us to report these cases.- - - - - - - - - - ranking = 4keywords = dermatitis (Clic here for more details about this article) |
8/13. lichen sclerosus et atrophicus of the oral mucosa.lichen sclerosus et atrophicus (LSA) is a relatively uncommon dermatitis mainly affecting the vulva. Oral involvement appears to be rare. A case of oral LSA without concurrent genital or skin lesions in a patient with vitiligo and hyperthyroidism is described, together with a review of the literature.- - - - - - - - - - ranking = 1keywords = dermatitis (Clic here for more details about this article) |
9/13. Sutton's summer prurigo: a morphologic variant of atopic dermatitis.We describe in detail 6 of 18 children affected by a recurrent summer papular eruption on the elbows, knees, and backs of the hands. In all six, family history, clinical observation, or laboratory data revealed signs of atopy. Phototesting, performed to evaluate the role of ultraviolet rays in the pathogenesis of the disease, gave results similar to those obtained in subjects with atopic dermatitis. Therefore we suggest that this disease may be a peculiar morphologic variant of atopic dermatitis.- - - - - - - - - - ranking = 6keywords = dermatitis (Clic here for more details about this article) |
10/13. dermatitis herpetiformis and vitiligo.We report the fourth case of coexisting dermatitis herpetiformis and vitiligo. This patient's HLA haplotype is HLA-B8 DR3, which is characteristic of dermatitis herpetiformis. The autoimmune features of both disorders suggest that their coexistence is not coincidental.- - - - - - - - - - ranking = 2keywords = dermatitis (Clic here for more details about this article) |
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