| A 25-year-old homosexual black male presented with asymmetrical perianal ulceration of uncertain clinical origin. Indepth microbiological examination revealed the combined presence of haemophilus ducreyi and treponema pallidum. The atypical clinical appearance may have been due to the changed immunological status of the host's being infected with Human Immunodeficiency Virus. ( info) |
2/16. Inguinal bubo: problems in diagnosis. Two of the four patients with tropical venereal diseases underwent incision and drainage of the inguinal bubo resulting in discharging sinus before they were referred to the skin Clinic. Clinical diagnosis was made in all four but could not be confirmed. With appropriate therapy resolution was achieved without complications. The difficulties in arriving at and establishing the diagnosis are discussed. ( info) |
3/16. Multiple sexually acquired diseases occurring concurrently in an hiv positive man: case report, diagnosis and management. A case of an hiv positive man with multiple sexually acquired disease occurring concurrently is described. risk behaviours that could have predisposed him to hiv infection are discussed. The factors which might have interacted to make the sexually acquired infections severe and difficult to treat are postulated. ( info) |
4/16. Intravenous single-dose ceftriaxone treatment of chancroid. The antimicrobial susceptibility of haemophilus ducreyi varies according to the geographic region. Increased resistance to trimethoprim and/or sulfamethoxazole led the Centers for disease Control to recommend 250 mg ceftriaxone as a single intramuscular dose for chancroid. Intravenous or muscular routes of administration result in equivalent bioavailability. To avoid side effects such as syringe abscess and lidocaine intolerance, we prefer intravenous ceftriaxone therapy. The efficacy of this regimen is reported in 3 cases of chancroid. The intravenous administration of 1 g of ceftriaxone in chancroid seems to be as effective as administration by the intramuscular route, but it may lower the risk of syringe abscess, lidocaine intolerance and the emergence of resistant strains. ( info) |
| chancroid, as the name implies, is like a chancre. Unlike the painless chancre of syphilis, it is painful, darkfield negative, and does not respond to penicillin therapy. The number of cases have continued to rise in recent years. Because it can cause irreversible anatomical destruction, making the correct diagnosis is important and can prevent chronic morbidity. ( info) |
6/16. Imported pedal chancroid: case report. A man aged 22 who had returned from the fiji islands to denmark had chancroid on the left foot, but no history or sign of primary genital infection. The pedal location only is an unusual presentation of the disease, which was diagnosed only microbiologically. Chronic tropical ulcers therefore demand special microbiological attention. ( info) |
7/16. chancroid: clinical variants and other findings from an epidemic in Dallas County, 1986-1987. Dallas, texas, recently joined the ranks of cities in the united states that have been plagued by outbreaks of chancroid. This article describes an epidemic of chancroid in Dallas County and presents cases that illustrate the spectrum of clinical illness that this venereal disease can produce. Also reviewed are the current diagnostic and therapeutic methods of managing patients with chancroid. ( info) |
| chancroid, a disappearing disease in the united states, was reintroduced into the country in 1980 by immigrants from the Caribbean, mexico, and Southeast asia. Point epidemics resulted, each of them associated with prostitution. During the 4-month period between March 1 to June 30, 1985, forty-five patients were diagnosed and treated in massachusetts, thirty-seven from boston alone. By means of these case records, the morphologic characteristics, laboratory diagnosis, and treatment regimens are described. ( info) |
| Auto-inoculation from a genital ulcer suspected of being ulcus molle gave redness after 24 hours and after 48 hours vesicles and pustules appeared. Cultivation from the auto-inoculation after the 48 hours was positive for herpes simplex virus type 2. Our observation underlines two points: auto-inoculation for the diagnosing of haemophilus ducreyi infection may be mimicked by herpes simplex infection, and the incubation period of herpes simplex can be shorter than the 4-5 days usually given. ( info) |
| A case of Hemophilus ducreyi infection clinically resembling granuloma inguinale is reported. culture of the causative organism permitted a definitive diagnosis to be made. Combined treatment with tetracycline and sulphamethizole/trimethoprim rapidly cleared the infection. ( info) |