| A case of granuloma inguinale (GI) presenting as a lateral neck mass in a 4-month-old, hiv-positive infant is described. The histological features of the mass were typical of GI, with numerous macrophages containing intracellular organisms with a "closed-safety-pin" appearance. This is a rare occurrence, and the mode of transmission of infection is discussed. An awareness of GI in infants by both clinicians and pathologists is important to prevent morbidity and allow for prompt institution of appropriate treatment. ( info) |
2/46. granuloma inguinale simulating advanced pelvic cancer. This paper describes a case of multiple disease in an Aboriginal woman. granuloma inguinale, of unusual severity and extent, which closely simulated advanced pelvic malignant disease, was included. Some problems of the diagnosis are discussed. ( info) |
3/46. Dorsal perforation of prepuce: a common end point of severe ulcerative genital diseases? Severe ulcerative genital diseases can cause destruction of the prepuce, glans, or sometimes of the whole penis (phagedena). We observed a characteristic pattern of partial destruction of the prepuce as a result of a wide variety of ulcerative genital diseases. Five patients, two with severe genital herpes, one with hidradenitis suppurativa, and two with donovanosis presented with perforation on the dorsal surface of the prepuce. In four of them, the glans protruded through the defect and in one, the defect was not large enough to allow protrusion of the glans. In two patients, the preputial sac was obliterated. The relatively decreased blood supply of the prepuce is the probable explanation for perforation at this selective site. ( info) |
4/46. An uncommon cause of a destructive vulval lesion. We present a case of a 39-year-old woman with a vulval lesion, which macroscopically looked consistent with a fungating squamous cell carcinoma of the vulva. However, further investigations demonstrated a less common cause for this presentation. ( info) |
| granuloma inguinale is an uncommon infectious granulomatous disease of the inguinale area that can insidiously engulf and mutilate tissue. The reported case of granuloma inguinale demonstrated the painless progression of the disease to destroy most penile, scrotal, and inguinal tissue and also showed the subsequent satisfactory therapeutic result with antibiotic treatment. light microscopy of plastic-embedded thin-sectioned tissue specimens allowed clear demonstration of the Donovan bodies and may be valuable in diagnosis. ( info) |
| Donovanosis is a sexually transmitted infection which presents with genital ulceration and inguinal lymphadenopathy. Rarely, it presents with extra-genital manifestations. We present a case of disseminated donovanosis with cervical ulceration, massive pelvic lymphadenopathy, osteomyelitis of the wrists and septic arthritis of the knees and right elbow. A 23-year-old gravida two presented with wasting, oedema, ascites, bilateral iliac lymphadenopathy, anaemia and a large ulcer of the cervix uteri. Two months later in the outpatient clinic, she was much improved but still had post-coital bleeding and a hyperaemic cervix, suggestive of persistent infection. The course of antibiotics was therefore repeated. Histopathological examination of a specimen from colposcopic biopsy of the cervix uteri revealed granuloma inguinale. She improved after several courses of antibiotics, blood transfusion, surgical debridement and aspiration of affected joints. ( info) |
| granuloma inguinale (GI) is a sexually transmitted disease seldom seen in the united states and canada. We are reporting three cases recently seen in Toronto, ontario, two in immigrants, and one in a native born Canadian who had an intimate relationship with a foreign visitor. The basic features of the disease are discussed. ( info) |
| The authors present a case of disseminated granuloma inguinale with bilateral psoas abscesses. infection with calymmatobacterium granulomatis is usually localized to the genital organs but rarely may be disseminated. A search of the literature revealed that only two cases of psoas abscesses due to calymmatobacterium granulomatis were previously reported ( info) |
9/46. Donovanosis (granuloma inguinale) of the oral cavity. A female patient suffering from donovanosis of the oral cavity without associated lesions elsewhere is reported. The importance of remembering donovanosis in the differential diagnosis of chronic granulomatous ulceration of the mouth is emphasized. ( info) |
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