FAQ - Adenoma, Bile Duct
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What are the reasons for stone in Common Bile Duct ?


After surgery of Gall Bladder.
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This is a gallstone - even after having your gallbladder taken out it is possible to still have a stone left behind in the bile duct or for a stone to form in the duct later. Happens because the make-up of your bile (liquid produced by liver to help dissolve fats) is prone to forming stones. Some risk factors include being overweight, fair skinned, fertile/pregnant, female and aged over 40, but other people get them too. A stone in the duct can cause jaundice and inflamed pancreas, so it may need to be removed. HTH  (+ info)

Still trying to get some answers for bile duct cancer diagnosis.?


loved one diagnosed with bile duct cancer two weeks ago, Has been hospitalized for tests. Recently the doctors said that it has not spread and will start next week with radiation to the site. This sounds promising to the family. Could this be a good sign? Anyone have any more info for us.?
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Well it's always a good thing that it hasn't spread...So your saying its only in the duct..not the gallbladder, liver or duodenum or the pancreas right?(The gallbladder is like a storage place for bile that the liver has made, the bile is then secreted into the duodenum..that attaches the stomach to the begining of the small intestines..its considered part of the small intestines...if you didnt know). Anyways...just be supportive to your loved one and assist him/her in following all doctors orders prior, during and after treatment...good luck  (+ info)

i underwent hepaticojejunostomy for cyst in bile duct in 2007. want to know the after effects/?


this surgery has left a thick scar(roof top cut) in my abdomen and I am too scared to go for a child. what kind of complications can arise out of it. if at all C-section is required, what should i expect.
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Who was the football player that died of Common bile duct cancer?


Pro Football Hall of Famer, Walter Payton, died November 1, 1999 from bile duct cancer.

http://en.wikipedia.org/wiki/Walter_Payton  (+ info)

What produces bile that is secreted into the duodenum via the bile duct?


The Liver.

Of course, some might say "The Gallbladder." They would be wrong. This may, or may not, include your teacher. Probably does, if you're publicly schooled.

While the gallbladder EXCRETES bile into the duodenum, it is the liver that SECRETES bile, which gets stored in the gallbladder.  (+ info)

What conditions would a bile duct be removed after already having the gall bladder removed.?


It wouldn't be removed normally. Some of the stones from the gallbladder could have plugged in up. Normally, if the doctor suspects this, he'll shoot dye through the duct to see if it comes out the other end. If something is in there, a few procedures exist to clean it out.

Occasionally, people have been known to get a stone in the duct long after surgery. Normally, a doctor will scope the upper GI tract to remove the stone and fix the duct.  (+ info)

How do i effectly do a liver cleanse/bile duct cleanse?


corrrected spelling...effectively...i was typing way too fast
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I am not sure you can although I am sure someone will disagree with me. your liver is your bodies metabolizing organ. everything you ingest gets picked through by your liver.
What ever you chose to "cleanse" with has to be meabolized by your liver. Thats like cleaning the toilet with more pooh.
Not taking lots of drugs(OTC medication included) not eating lots of fat,don't drink lots of alcohol, drinking plenty of plain old water, eating foods with little or no chemicals involved will all help your liver.
The best way to clean it is to not put bad stuff in it.  (+ info)

Will my bile duct always remain collapsed?


My bile duct requires a stent in it continuously due to its collapse. It is collapsed due to a neuroendocrine tumor on my pancreas. If it does not have a stent in it, within months I will start to lose weight and have severe diarrhea. My body will eventually start taking protein from my muscles and I will get a body itch in the strangest places on my body. It does not matter what or how much I eat because my body will not be able to absorb nutrients due to the bile duct's collapse.
Will my bile duct always stay collapsed even if the tumor shrinks dramatically or is removed? SERIOUS ANSWERS ONLY PLEASE.
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This is an incredibly complex topic and you have supplied almost NO information to go on. Therefore you get an entirely abstract answer... which is for the best. You cannot get specific answers to questions regarding YOUR TREATMENT over the internet, unless your doctor happens to catch you posting questions online!

The reason that tumors of the head of the pancreas affect the bile duct is that the bile duct actuall PASSES THROUGH the head of the pancreas on its way into the intestine. The bile duct and the pancreatic duct join together just as they enter the intestine in the second portion of the duodenum... just a few inches after the stomach turns into tubular bowel.

When a tumor compresses the bile duct from the outside, this leads to blockage and bile cannot get out of the liver. Bile has a few jobs to do, and one of them is to rid the blood stream of oily waste products. The yellow discoloration that one suffers from bile duct blockage is called "jaundice". It represents an accumulation of bilirubin which is a waste product that comes from the normal turn-over of red blood cells.

If a patient is found to have a tumor in the head of the pancreas which blocks the bile duct, the next question that the doctor has to ask is, "is this tumor removable with surgery or not?" If it is, we call it "resectable", and if not, we call it "unresectable".

The decision to persue a surgical approach for tumors in the head of the pancreas is one that requires a huge amount of aggression on the part of the surgeon. The removal of the head of the pancreas takes with it a variety of tubular organs that are too attached to the pancreas for them to be left behind. This operation is called a "pancreaticoduodenectomy" and is reffered to as the "Whipple procedure" named after one of it's earliest proponents. This operation typically takes between 4 and 10 hours to perform and has a very high complication rate. Reconstruction of the gastrointestinal tract, the biliary flow pattern and the emptying of the pancreas into the intestine are all required. Any leaks at the points where these systems are rejoined can be disasterous, especially the pancreas-to-intestine junction. Pancreatic juice turns out to be especially nasty.

Because this operation causes so much illness, it is not undertaken lightly. If the surgeon notices anything which would indicate that the tumor is stuck to something that has to be left behind, or if it has escaped from its primary site in the pancreas and has begun to grow in the liver or in distant lymph nodes, then the operation is aborted because it's pointless to hurt the patient that much if its not going to offer a reasonable chance of increasing lifespan.

Backing up a step, the most common cancer that leads to the need for a Whipple pancreaticoduodenectomy is pancreatic adenocarcinoma. This is cancer that arises from the lining of the pancreatic ducts. The next most common cancer that would lead to this operation would be bile duct cancer that happens to grow within the head of the pancreas. Bile duct cancer is called cholangiocarcinoma.

The pancreas has two components. One component is "exocrine", which is the part that makes digestive juice and puts it into a duct system that eventually pours it into the gut to mix with food. The other part is "endocrine". Endocrine function involves hormone formation. The pancreas has little tiny clusters of cells which make hormones. These hormones are not released into the intestine to mix with food. Instead, they are released into the blood stream and circulate throughout the body, interacting with different cells as a signalling mechanism. These little nests of cells are called "Islets of Langerhans" and when they give rise to a tumor, its a completely different situation, physiologically, than adenocarcinoma arisen from pancreatic ducts.

One of the most important questions we have to ask, when it comes to the assessment of such a "neuroendocrine" tumor is whether or not it secretes hormone. Sometimes the uncontrolled release of hormone can cause problems that are in organs completely remote from the location of the tumor. For example, a gastrin secreting tumor (gastrinoma) can cause ulcers in the stomach. Insulinoma can cause dangerous hypoglycemia. VIPoma (secreting vasoactive intestinal peptide) can cause a syndrome of diarrhea and electrolyte disturbances. However, many pancreatic endocrine tumors are "nonfunctional". They may or may not be secreting some sort of hormone product, but if so, its so mutated that it has no noticeable physiologic effect.

When it comes to the assessment of resectability for a neuroendocrine tumor of the pancreas, there are a tremendous number of variables involved. First off, is there any way to get complete control of the lesion, surgically. If the tumor is stuck to something important like the superior mesenteric artery (which we're not allowed to remove since this would kill all of the absorbing intestine and kill the patient) then we call it unresectable. If it's obviously in multiple places in the body, it's unresectable. If the patient is in poor health and would not tolerate an enormous operation, then it doesn't matter how favorable the tumor's anatomy is, it's unresectable in the sense that the patient wouldn't tolerate the resection.

If there is no way to go after the lesion surgically, then we fall back on plan B. Plan B typically involves insuring that the bile duct stays open, the intestinal tract stays open, and that any medical consequences of the tumor are managed appropriately. Pancreatic cancer can be painful. There is no reason that the patient should be delivered inadequate pain control.

In some neuroendocrine tumors of the pancreas, getting less than all of it surgically is still an acceptable alternative. This is called "debulking" and is of no benefit in terms of overall survival time. However it IS of benefit in terms of symptom control. For those who are suffering the effects of cancer related hormone imbalance, this can be a real benefit.

It would seem to me that if you're being managed with a biliary stent, then you're in a sort of "plan B" mode for some reason or another. It may be related to the specifics of your tumor, or it may be that it relates to your underlying health.

I hope this answers some of your questions. I encourage you to engage your surgeon in an open conversation on the topic!

Feel free to contract me directly through yahoo answers if there is anything I can help with in terms of information interpretation.  (+ info)

Anyone know which chemo is more affective for Bile Duct cancer?


ideas?
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No one - not even the best experts - can predict which chemotherapy regimen will be the most effective for the one special person you are asking about. It is always an educated guess. In many cases, nothing works well - but people often want to try if surgery alone is not sufficient. The medical oncologist who knows all the details of this patient's medical history is the person to make the guess.

From http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Chemotherapy_69.asp?rnav=cri
"Drugs used to treat bile duct cancer
Several drugs can be used to treat bile duct cancer. In some cases, 2 or more of these drugs may be combined to try to make them more effective. The drugs that have been used most often to treat bile duct cancer include:"
* 5-fluorouracil (5-FU)
* gemcitabine
* mitomycin C
* doxorubicin (Adriamycin)
* cisplatin
* capecitabine
* oxaliplatin

Wiki is fairly good for this too http://en.wikipedia.org/wiki/Cholangiocarcinoma
"The majority of cases of cholangiocarcinoma present as inoperable (unresectable) disease in which case patients are generally treated with palliative chemotherapy, with or without radiotherapy. Chemotherapy has been shown in a randomized controlled trial to improve quality of life and extend survival in patients with inoperable cholangiocarcinoma. There is no single chemotherapy regimen which is universally used, and enrollment in clinical trials is often recommended when possible. Chemotherapy agents used to treat cholangiocarcinoma include 5-fluorouracil with leucovorin, gemcitabine as a single agent, or gemcitabine plus cisplatin, irinotecan, or capecitabine. A small pilot study suggested possible benefit from the tyrosine kinase inhibitor erlotinib in patients with advanced cholangiocarcinoma."  (+ info)

How can a stone of size 1.3cm in GB bile duct pass off without any pain?


It is possible- but probably not probable. Did you talk to the dr. about getting the stone blasted by lazar?  (+ info)

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