FAQ - Carcinoma, Transitional Cell
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Can I have a basal cell carcinoma on my foot?


Has this happened to anyone, what I thought was a wart is infact a basal cell carcinoma. How was it treated if this happened to you. Thanks.
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Skin cancer is a major problem in the elderly. Squamous cell carcinoma (SCC), the second most common skin cancer, typically occurs in this age group. Despite a number of modalities readily available for treatment. Consequently, the search for novel treatments continues. To my knowledge, there are only 6 published reports of invasive SCC treated with 5-percent Imiquimod cream. (Imiquimod is a topically applied imidazoquiline immunomodulator that enhances both innate and cell-mediated immunity )
This is a clinical trial result that has details that may be of interest:- An 89-year-old woman presented with three lesions on her lower limbs. She had previous treatments for multiple basal cell carcinomas, actinic keratoses, Bowen disease, and invasive SCCs at various sites. The new lesions were on the left foot (one) and right lower leg (two) and all showed changes of poorly differentiated SCC histologically. She declined surgical excision; radiotherapy was felt to be a poor option. She was treated with 5-percent imiquimod cream, initially to just the lesion on the dorsum of the foot, for 8-12 hours at night for three nights each week (three times a week). Treatment was well tolerated by week 2, so the frequency was increased to five times a week, and all three lesions treated. Gradually, two lesions diminished in size. Treatment was continued until there was no clinical evidence of residual tumor at these sites (19 weeks) repeat biopsies showed only a focus of dysplastic cells with no invasion (dorsum, left foot), and epidermal hyperplasia with no significant cytological atypia (outer aspect, right lower leg) Neither now showed evidence of invasive SCC. After 16 months there was no recurrence of either lesion. The third lesion (right lower leg,) did not respond to topical imiquimod and was later surgically excised.
Hope this helps
Matador 89  (+ info)

Has anyone had any experience in a cancer treatment called Torisel for Renal Cell Carcinoma?


My dad was diagnosed with Stage 4 Renal Cell Carcinoma. He started a treatment this week. The treatment is call Torisel. I wonder if anyone has any experience in this drug. If it worked for your loved one and if there was any side effects and how long did it take to have the side effects.
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I believe this is one of the newer mTOR targeted therapy drugs. It is very new. You would probably get more response and better information by going to an online support group with other patients who are using this drug. Good luck.  (+ info)

What is the life expectancy for small cell carcinoma?


Hi. My mom was just diagnosed with small cell lung carcinoma (SCLC) and it is in the early stages THANKFULLY! however, i am only 17 and she is hesitant about giving me info and telling me what the future holds for our family, especially since she is a single parent. If you could please give me some info to help me better understand and how to help my mom beat this disease i would forever grateful!!! Life expectancy, treatment, and any encouragement techniques as she is very depressed. thank you all!!!!!!
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Small cell grows quickly, much quicker than non small cell. but small cell responds better to chemo treatments. Your mom may be advised to also have WBR (whole brain radiation) as often lung cancer travels to the brain. Since caught very early, she has a good chance of ridding herself of cancer, but will have to have regular scans as recurrence is almost always. Attached is a yahoo lung cancer group, there you will find people that have beaten small cell and are still surviving and are N.E.D. (no evidence of disease) after a couple of years of treatment.  (+ info)

Anyone had any experience with High Grade Small Cell Neuroendocrine Carcinoma?


Diagnosis is High Grade Small Cell Neuroendocrine Carcinoma presenting between colon and pelvis (also in lymphnodes in same area). Doctor's are not sure but believe it originated from cervix or uterus. It is being treated as if it were Small Cell Lung Cancer eventhough it is NOT in the lungs.

Having a hard time finding anything online because it is apparently pretty darn rare. Any information would be greatly appreciated.
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This is not that uncommon. Neuroendocrine cells are all over the body so it can arise in many places other than lung (most common). It is described as small cell carcinoma, an while usually lung, can arise in many sites such as vagina, cervix, rectum, intestine, appendix, etc. They are all generally treated the same, using common small cell lung cancer regimens.
In general, limited stage disease, loosely defined as disease that can fit within one radiation portal, can be cured occasionally with chemotherapy and radiation- but this is extrapolating from lung cancer patients, where cure rates are <20% with limited stage disease. More extensive disease is not curable, though it does respond very well to chemotherapy or radiation or both.

Blessings  (+ info)

Can chewing tobacco cause Squamous Cell Carcinoma?


We just recently found out that a family member has Squamous Cell Carcinoma and the doctors think it maybe from chewing.
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What is the survival rate of renal cell carcinoma patients who have had nephrectomy?


Diagnosis was renal cell carcinoma. Right kidney was removed with a radical nephrectomy.
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since the affected kidney has already been removed, you have already "upped" your chances of survival. there is now a higher probability of recovering. however, precaution should still be exercised. visit your doctor and have a follow up exam to check wether the surgery was a success and if it was done in time to prevent the spread of the disease. since carcinoma is often caused by too much "bad" carbon in the body, you would do well by not eating "burned meat" that usually happens when cooking in open fire-such as when grilling. good luck!  (+ info)

Basal cell carcinoma surgery and skin graft - anyone else had the same?


I've had a full thickness skin graft for a basal cell carcinoma on my left temple on my face, but after 3 months, my wound site where the cancer was (not the skin graft site) is still painful. Anyone else had this?
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I had a basal cell carcinoma on my nose removed April 3rd 1991.
Now its beginning to peel. I've made arrangement to see a skin specialist.
I would suggest you do the same. It can be very painful. The likelihood of the cancer coming back, while still in the back of our minds, is minimal at best, its still there and very real, and very scary. Go see your DR. its important. And refrain from being in the sun. Your to important/special to not go see about it.  (+ info)

A few months ago I got my Basal Cell Carcinoma removed and it has been stinging. Is that normal?


A few months I was told that I had Basal Cell Carcinoma and went down to the doctors and they removed it by cutting out the cancer spot. It was between the size of a eraser head and a dime. It has been stinging a lot lately and feels extra sensitive. I don't know if that is normal or not. Does anyone know what it should feel like as time goes on?
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My family dr removed a mole and it was basel cell carcinoma. Could he have gotten all the cancer?


I am going to a dermatologist whom specializes in skin cancer, what is the chances i will have to have surgery?
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There are many types of skin cancer. Some are very dangerous and some are not. My father has a cancerous mole removed and he was fine. Others are not so lucky. The problem with some skin cancers they go deep into the tissue and will require further treatments. Your dermatologist will explain what treatment plan if any he will advise for you. Tanning beds are very harmful stay away from them and also from the sun. Keep covered as much as possible.  (+ info)

How can I start a cancer support group for renal cell carcinoma?


Where could we meet?
How large of a space would I need?
How can I get speakers?
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Do you or someone in your family have renal cell carcinoma?

You can contact your city's local hospitals to see if a support group for that type of cancer already exists. If the group does not exist, you can ask to speak with the hospital's community relations director or volunteer director to talk about your interest in starting a support group. But there are guidelines and funding involved b/c you will have to find a room in a hospital to use and may have to pay the hospital to use it, unless you are told otherwise. And your hospitals may have cancer ward or unit that you can check out in person too, to see if there are support groups there and speak with the people or organizations who lead those support groups, to get an idea how you would create one. You would also have to advertise for volunteers to lead the support groups on specific nights, etc.,.

Your best bet is to find an existing cancer support group and either do an informational interview with the person in charge, or do research online to start with.  (+ info)

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