Does anyone else have hypogonadotropic hypogonadism?
If so, what symptoms and what kind of treatment do you receive?
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Hypogonadotropic hypogonadism describes absent or decreased function of the ovaries (in men, it would be the testes). This disorder results from the absence of the gonadal stimulating pituitary hormones follicle stimulating hormone and luteinizing hormone.
The hypothalamus secretes GnRH (gonadotropin releasing hormones), which stimulate the pituitary gland. In response to the GnRH, the pituitary gland secretes other hormones (the FSH and LH). These hormones in turn, stimulate the ovaries to secrete still other hormones that are responsible for normal sexual development in puberty. Any disruption in this chain reaction causes a deficiency of the sex hormones and halts normal sexual maturation. Failure of the hypothalamus is most commonly a result of Kallmann syndrome, an inherited disorder that usually includes a disorder of the sense of smell. Failure of the pituitary may result from empty sella syndrome, pituitary tumors (craniopharyngioma), head injuries, or other causes.
Turner Syndrome and in men, Klinefelter Syndrome, can also be causes, along with other causative factors - see http://www.emedicine.com/PED/topic1118.htm.
Symptoms include lack of development at puberty, incomplete development or significant delay of pubertal development, absence of secondary sexual development (for example, pubic, facial, and underarm hair),
short stature and
sometimes, the inability to smell
Treatment depends on the source of the problem and include estrogen and progesterone replacement (HRT) and GnRH injections (i.e., Lupron).
Hypergonadotropic hypogonadism is more common in males.
With proper hormonal stimulation, puberty can be induced and fertility may be restored. For a detailed overview of various other treatments and background info, see http://www.emedicine.com/PED/topic1118.htm. (
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could a urinary tract infection cause hypogonadism?
what other types of infection could cause hypogonadism?
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I do not know other causes but i know that urinary tract infection may cause hypogonadism! (
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does any one know if hypogonadism (in men ) would keep someone from being able to join the army?
no rumors please, you either know for sure or you don't.
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I'm too old for the army but I do have hypogonadism. I do think that any man with this problem would be deemed too unfit to join. But just ask recruitment at your local army or armed forces branch.
The natural outcome of this condition as present in women does not stop them from joining up, though, does it? Maybe the army could start a transvestite division. (
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i am 26 and have been diagnosed with hypogonadism now can this be fixed?
i am not interested in having to get shots the rest of my life. also i am my oldest sons only parent his mom wants nothing to do with him so i been playing mom and dad to him and i dont want that to change. but i need this i dont sleep right i been gaining weight my blood pressure is up and have no sex drive which puts a huge strain on my marraige amd am tirred of having no energy. and this costs 100 a month on a regular basis. i dont know what to do does anyone have any advice?
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Before I begin, I am not a doctor, and can only give information you'd find from reputable sources, not professional medical advice...
It depends on what caused the low testosterone. Sometimes, a single instance of low testosterone can occur from illness, lack of sleep (tends to decrease testosterone about 25%), dieting, exposure to paint thinners, use of painkillers, use of cortisone like steroids,
etc. If there is a consistent pattern (i.e. a second test with a similar or even lower result), then options are mostly medication oriented. (With that said, there is the exception that a sedentary lifestyle &/or being overweight can lower testosterone, and improving diet while having a more active lifestyle, including weight lifting, can raise it.)
You should get other hormones tested to see what might be causing low testosterone.
1) Hyperestrogenism- High estradiol (estrogen) can lower testosterone.
Aromatase is an enzyme that converts testosterone to estrogen, and it aromatase can be found both in fat and in the testes. Losing body fat can reduce how much estrogen gets made (and estrogen tells the pituitary not to demand as much testosterone from the testes. Specifically, it decreases LH [and FSH] from the pituitary). There are studies that show medications can increase testosterone by lowering estrogen, either using an aromatase inhibitor like Arimidex or a selective estrogen receptor modulator like Nolvadex. However, many doctors (especially endos) are reluctant to give such medications to men.
2) Primary hypogonadism- the testes themselves simply can't make enough, despite stimulation from pituitary hormones (gonadotropins LH and FSH). When testosterone is low and gonadotropins are high, this indicates the testes will not respond to stimulation therapy (such as hCG, hMG, clomid, etc.), and one requires testosterone itself. (I'll detail testosterone options further below.) This, unfortunately, can compromise fertility prospects, but some men still produce enough sperm post-testosterone replacement therapy (TRT) to sire a child.
3) Secondary hypogonadism- the pituitary itself does not produce enough LH and FSH to signal the testes to do their job. This can happen from diet, stress, overexercise, lack of sleep, etc, but if the pituitary continually fails to produce these gonadotropins, the problem must be addressed medicinally. Sometimes the cause is a benign pituitary tumor called a prolactinoma, which produces too much prolactin. One can try Dostinex or Bromicriptine to combat excess prolactin and restore testosterone production. Sometimes, however, decreasing prolactin alone does not increase testosterone production. As mentioned above, hCG, hMG, or simply recombinant LH may be options to maintain testicular size and production of testosterone from the testes themselves.
As for methods of testosterone administration, there are shots, pellets, gels, creams, buccal tablets, & patches. Pills generally don't elevate testosterone very well, and are generally not used in the US. Creams and shots are the least expensive (even without insurance), whereas pellets and gels are the most expensive. In my opinion, shots are probably the best option 1) to elevate testosterone enough to find improvement while maintaining other hormones where they should be, 2) to minimize cost, and 3) to minimize risk of transferring testosterone to people via contact. Injecting testosterone should cost around $120 per 4 months, making it around $30 a month (not counting syringes and other inexpensive medical supplies).
I belong to a Yahoo! group that addresses the issue of low testosterone, including how to treat it. (http://health.groups.yahoo.com/group/hypogonadism2/) (
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can malnutrition cause permanent side effects like hypogonadism?
Haven't seen a study done on this topic, but unless malnutrition was a prolonged or lifelong issue, I doubt it would have such permanent effects. (
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how is hypogonadism treated if the cause of it is malnutrition?
You would be better suited to consult a doctor for this information. (
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what is the effect on woman's health married to man with hypogonadism and subjecting wife to mental torture?
cant be to good..ummm hell? (
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what is the prognosis of hypogonadism and young male with severe learning dificulties?
Hypogonadism would not cause the severe learning difficulties, although it may be secondary to the cause. If you can give the reason for the learning difficuties you may get a better answer; (
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15 years old male presented by stunted growth, short stature, hypogonadism, non scaring scalp and eye brow alo
the patient is the third sibling of consanguineous marriage. his two older brothers died by a similar condition in early childhood
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What's your question? (
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how effective is testosterone replacement therapy when treating hypogonadism/low testosterone?
Well for me I went from 8yrs of different pills being shoved down my throat for depression and what not. They even tried to tell me I was bipolar. After I got in touch with my trt doc I have felt GREAT. I am a avid supporter of this as it saved my life and my marriage. testosterone is what makes "us" US
Let me know if you want my doc hes licensed in all 50 states. Just leave some way to contact you in a comment. (
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