What does "mast cell degranulation" means?where can I get more information about it?

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I need information about this clinical disorder and what are the potential triggers of mast cell degranulation or mast cell leukemia or mastocytosis. Thanks.
Mast cell degranulation is where the mast cells break down and release histamine and heparin which then causes all sorts of very unpleasant severe immune and allergic reactions. Mastocytosis is characterized by excessive mast cell infiltration of either the skin or extra cutaneous organs. Death from mastocytosis is secondary to mast cell degranulation.
Read up here about mastocytosis.

http://www.emedicine.com/derm/topic258.htm

http://www.emedicine.com/med/topic1401.htm

http://www.emedicine.com/derm/byname/mastocytosis.htm  (+ info)

I am seeking information on ways to reduce white cell counts in Chronic Lymphatic Leukemia?

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are there any herbals.naturopathic,mineral suggestions in assisting the reduction of white cell count for Chronic Lymphatic Leukemia?
Pranayam will help to reduce the white cell count in chronic lymphatic leukemia and will help the body to fight the cancer.Over long term you will recover fully.
The pranayam techniques:
Bhastrika - Take a long deep breath into the lungs(chest not tummy) via the nose and then completely breathe out through the nose.Duration upto 5 minutes.

Kapalbhati -(Do it before eating) Push air forcefully out through the nose about once per second. Stomach will itself go in(contract in). The breathing in(through the nose) will happen automatically. Establish a rhythm and do for 20 to 30 minutes twice a day.(Max 60 min/day) Not for pregnant women. Seriously ill people do it gently.

Anulom Vilom - Close your right nostril with thumb and deep breath-in through left nostril
then – close left nostril with two fingers and breath-out through right nostril
then -keeping the left nostril closed deep breath-in through right nostril
then - close your right nostril with thumb and breath-out through left nostril.
This is one cycle of anulom vilom.
Repeat this cycle for 20 to 30 minutes twice a day(maximum 60 minutes in one day).
You can do this before breakfast/lunch/dinner or before bedtime or in bed.Remember to take deep long breaths into the lungs.You can do this while sitting on floor or chair or lying in bed.

Bhramri Pranayam -Close eyes. Close ears with thumb, index finger on forehead, and rest three fingers on base of nose touching eyes. Breathe in through nose. And now breathe out through nose while humming like a bee.
Duration : 5 to 10 times

Only by doing you will benefit and will feel good that you can do something to help the body.Copy and print this to improve your technique and stay focused.This is simplified pranayam for everyone and you do not have to go to classes to learn. This is for life, unlike short term classes where you do it in the class then stop when classes are over.  (+ info)

What are the sypmtoms of lymphoblastic lymphoma and stem-cell leukemia?

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I am asked to make a donation for a citizen of my country, who is suffering from lymphoblastic lymphoma and stem-cell leukemia. I have made my donation already. However, I wish to know about the cause and symptoms of lymphoblastic lymphoma and stem-cell leukemia. Thank you
  (+ info)

Do Leukemia and Lymphoba always make the white blood cell count go up?

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I'm just wondering. When someone has Leukemia or Lymphoba, does it ALWAYS make someones white blood count go up? So would the raised white blood count be shown on a regular blood test?

Thanks a ton. >.<
Carol, thanks for that information, it was really helpful, but I'm wondering if it ALWAYS goes up when that disease is present in the body.

Thank-You!
I'm not as familiar with lymphoma as I am with leukemia. With leukemia white blood cell counts do NOT always go up. In some cases white counts are elevated, but in some cases they are unaffected or even low. In my son's case, his white blood cell count was very high when he was diagnosed with AML leukemia last December. His count may have been high because of the leukemia or it may have been high because he was trying to fight off a cold. In some cases, however, the bone marrow will slow down production or even cease production altogether. This can be true of any blood cells that are produced, not just the white blood cells.

I hope that answers your question, if you have any more questions of anything feel free to email me ([email protected]) or send me an IM (crazycanuckj).  (+ info)

What is the likely cause of general swelling 10 days after mast cell surgery on my dog?

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Entire area around incision (upper-back flank of Great Dane) is somewhat swollen (after 10 days of no problems). It is fluid filled and you can easily squish it from one side of his 7-inch incision to the other. (Vet used internal, dissolving stitches) No redness, sores, bumps, or discomfort. Temperature is normal (100.8). He seems to feel fine. No other symptoms at all. I will obviously take him in but the vet isn't open until tomorrow. I am looking for likely causes for this... ESPECIALLY: Does this mean the cancer is likely still there? Or is this probably some side effect of surgery not cancer related?
I would have said "infection" but then it would have been hot to the touch, and tender. So, probably the cause is still there, so tomorrow take him to the Vet, but call first and describe the problem, insist on speaking to the Vet himself. Lots of luck.  (+ info)

What is the normal T- Cell range? Can the T-Cell count be over the range without having Leukemia? ?

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My T- Cell count is 1900 above the normal limit. A doctor thought that the count could mean I have too many immature T cells. What type of Leukemia could I have?
T cells are a type of white blood cell. A measurement of the T-cells is often called a T-lymphocyte count.

The T-Cell count is made up of two components. First, there are what are called your helper T-cells, also known as absolute CD4+ or T4 count. These are the guys who initiate the body's response to invading stuff such as viruses -- they recognize the bad guys. In a healthy adult, the CD4 count should be somewhere between 600 to 1200 cells per cubic mm of blood. It tends to be on the higher side in children and women, and it fluctuates based on what's happening in your body.

There are also Suppressor T-cells, which is known as the absolute CD8+ or T8 count. These guys end the immune response -- they tell your body that all is ok, stop attacking now. The normal range for CD8 is 200 to 1,000 cells.

Some doctors prefer to look at T-cell count based on percentage; a normal CD4 cell percentage in a healthy person is about 30-60%, while a normal CD8 cell percentage is 15-40%.

Common causes of a raised T-cell count include mono, multiple myeloma (a cancer of the bone marrow more common in older people), and Acute lymphocytic leukemia (ALL). Here is some information from the Leukemia and Lymphoma Society on ALL:

http://www.leukemia-lymphoma.org/all_page?item_id=7049

Best of luck.  (+ info)

My husband was diagnosed with Mast Cell Disease and I trying to help him cope. But how, can anyone help?

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We are not sure what exactly it all intells. He looks up things all the tiime but no doctors on the military base know what they can do or what will help. He is going through a medical discharge but we are in germany right now trying to get back to the states but don't know what to do right now. I need help trying to help him cope with all this.
  (+ info)

Conditions (BESIDES LEUKEMIA) that cause a dramatic increase in white blood cell production?

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I need to name other conditions that could cause someone to have a very high white blood cell count in a hematocrit reading. Besides leukemia. Thanks!
Any serious infection, pneumonia ,pleurisy ,flu ,sepsis ,peritonitis,also the use of antibiotics, anti seizure drugs ,severe burns can also cause the white cell count to rise  (+ info)

What are the most promising alternative treatments for T-cell prolymphocytic leukemia?

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Subject has already gone through conventional treatments (chemo and radiation and stem cell infusion)
Homeopathic Treatment for Leukemia :-
ARSENICUM ALBUM 30, thrice a day half hour before meals along with FERRUM PHOS 6X,KALIUM PHOS 6X,CALCAREA FLOUR 6X,NATRIUM MUR 6X,SILICEA 6X and PHOSPHORUS 30 just once a day before going to bed. Homeopathic remedies do not interfere with your regular medication and they do not have any side effects and do not cause any complications. Email me if you need if there is anything you want to ask.
Take Care and God Bless you  (+ info)

How common is it for a child to be diagnosed with hairy cell leukemia?

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I read that it was most common for senior citizens to be diagnosed with the cancer. Has a child ever gotten it?
Yes, a child has ever gotten HCL.
You may want to read up on this article by Yetgin S, et al (2001). Relapse in hairy cell leukemia due to isolated nodular skin infiltration. Pediatr Hematol Oncol.18 (6):415-7. If you need the article, you can let me know. Hope it helps.  (+ info)

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