FAQ - Liver Cirrhosis, Biliary
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What are the physical signs of each stage of cirrhosis of the liver and are there 3 stages or more?


Someone I know has end stage liver disease and is still conscious and able to move around in a wheel chair. I was wondering how long she might have.
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The link below should help. I'm sorry about your friend.  (+ info)

what is the best treatment for primary liver cancer complicated with cirrhosis with portal thrombosis?


patient is a diabetic with low platelet count gastric verces are present. he has affected to primary liver cancer specially in right lobe with lot of nodules. if he get the treatment with radio frequency ablation will he stay with us for long period. what are the side effects of RFA?
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what is the life span of people with cirrhosis of the liver?


how long can people have cirrhosis of the liver without a liver transplant.
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I would see a doctor, as they are the only ones who can really give you an accurate lifespan w/o treatment, because i do not know your symptoms, your age, your eating/drinking habits. If your eyes become yellow you need to seek help immediately .
Up to a certain point, if the disease is stopped, the liver can regenerate. your best answer is seek help sooner then later, and get a transplant, b/c most die or cirrhosis waiting for one.  (+ info)

Someone I know has cirrhosis of the liver?


He also has Hep C, He has been on the list for a liver for almost a year now, he has deteriorated since. His mind and his body has changed. Can someone tell me what a bad liver does to the brain and physical changes of the body. He is very weak and just stares into space. How much longer can he wait before his body gives out. And do people like this die quietly at home or does some thing physical happen and needs to be rushed to the ER before they pass?

Please know your sources well, He is the father of my children.
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It depends. Not everyone dies the same way of the same complications. He could die in his sleep, or he could vomit blood (just an example). The liver processes the toxins out of your system. When it's not working (plus there's another disease that is attacking it) a person can go downhill fast.
As far as sources, these are 2 very reliable sites for information on both. You may want to print them out and take them if you go to the doctor with him. Because everyone's different--you should ask his doctor. I would assume it's pretty progressed already?

http://www.nlm.nih.gov/medlineplus/cirrhosis.html

http://www.cdc.gov/ncidod/diseases/hepatitis/c/  (+ info)

HELPP PLEASEE :( are the feedback mechanisms negative or positive in cirrhosis of the liver?


what exactly are feedback mechanisms? and are they positive or negative in cirrhosis of the liver? Also what are the feedback loops involved?
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Is cirrhosis of the liver the worst way to die?


I was talking with someone who told me about it. Is there a worse way to die?
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From my experience, yes. Usually the end stage is something called esophageal varicosies which essentially makes you bleed to death. Many times (not always) cirrhosis is caused by alcoholism or drug abuse. What compounds the situation is the people taking care of you, (I'm talking from experience here) don't feel that sorry for you if you were a drug or alcohol abuser. Although I never abused or neglected someone, I can honestly tell you they didn't receive any extras. Especially when they started having DT's and would hit you, spit at you and cause total disruption with their yelling, swearing, etc. Seek out an intensive care nurse and they can tell you more about all the tubes (blakemores, daisy catheters, etc) and procedures done during this end stage liver disease.  (+ info)

Is Cirrhosis of the liver a death sentence, even if the person stops drinking?


Please only answer if you have experience with this & list any credentials.
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No, it needn't be a death sentence:

http://digestive.niddk.nih.gov/ddiseases/pubs/cirrhosis/  (+ info)

what happens to the liver at the final stage of cirrhosis of the liver?


My mother-in-law just passed away due to this disease. She was diagnosed with it 5 years ago. Although she did not drink at all, what could have been the possible reason why she got it? Some people die right away when they are diagnosed, yet others last longer. At the end her kidneys started shutting down too. They did dialysis but did not work. Everywhere she had a cut or sore, blood started coming out. This was happening as we knew she was not making it. Blood came out from her eyes, ears etc. What was happening?
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There are a number of reasons people get cirrhosis which is scarring of the liver which makes it impossible for the liver to do its job. Some reasons are chronic hepatitis B C and D, autoimmune hepatitis (immune system attacks liver), inherited diseases, NASH (fatty liver that progresses to cirrhosis), primary biliary cirrhosis (immune system attacks the bile ducts), and iron overload. Then there are those people who do not have any reason for having the cirrhosis and fall into the category of cyptogenic (reason unknown).

When the liver slows or stops production of the proteins needed for blood clotting, a person will bruise or bleed easily. This happens in cirrhosis. Cirrhosis can also lead to kidney failure.

A person will die from cirrhosis when the disease has progressed to its final stage when total failure happens. At that point, only a liver transplant will save a person. The life span of someone with cirrhosis depends on many different things, so that's why some live longer than others. Example: Someone who has cirrhosis from being an alcoholic that stops drinking can slow down their disease very much and maybe even stop it. Someone with cirrhosis that continues to drink will progress to the end stage of the disease much quicker and it will certainly be fatal if drinking continues.

I'm sorry that your mother-in-law died from this terrible disease. Try to remember the good times you had with her. It must have been terrible to see her like she was at the end, so try not to focus on that. Focus on the good things.   (+ info)

3. Cirrhosis of the liver, a disease commonly associated with alcoholism, obstructs blood flow through the hep


3.Cirrhosis of the liver, a disease commonly associated with alcoholism, obstructs blood flow through the hepatic blood vessels. As a result, the blood backs up, and the capillary pressure greatly increases in the organs drained by the hepatic portal system. What effects might this increasing capillary pressure produce, and which organs would it affect
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Cirrhosis rarely causes signs and symptoms in its early stages. But as liver function deteriorates, you may experience fatigue, nausea, unintended weight loss, and swelling in your legs and abdomen. In time, jaundice — a yellowing of your skin and the whites of your eyes — and intense itching can develop. You may also experience bleeding from your digestive system that could be severe.
Complications
Because cirrhosis disrupts the normal function of your liver, it can cause a number of serious complications:
* Increased pressure in the portal vein. Blood from your intestine, spleen and pancreas enters your liver through a large blood vessel called the portal vein. If scar tissue blocks normal circulation through the liver, this blood backs up, leading to increased pressure within the vein (portal hypertension).
* Enlarged veins (varices). When circulation through the portal vein is blocked, blood may back up into other blood vessels — mainly those in your stomach and esophagus. Sometimes veins also form around your navel and at the rectum. The blood vessels are thin-walled, and because they're filled with more blood than they're meant to carry, are likely to bleed. Massive bleeding in the upper stomach or esophagus from these blood vessels is a life-threatening emergency that requires immediate medical care.
* Fluid retention. Liver disease can cause large amounts of fluid to accumulate in your legs (edema) and abdominal cavity (ascites). Edema is especially common in alcoholic cirrhosis. Several factors play a role, including portal hypertension and changes in the hormones and chemicals that regulate fluids in your body. Ascites can be uncomfortable and may interfere with breathing. In addition, abdominal fluid may become infected and require treatment with antibiotics. Although not life-threatening in itself, ascites is usually a sign of advanced cirrhosis.
* Bruising and bleeding. Cirrhosis interferes with the production of proteins that help your blood clot and with the absorption of vitamin K, which plays a role in synthesizing these proteins. As a result you may bruise and bleed more easily than normal. Bleeding in the gastrointestinal tract is particularly common. Cirrhosis may also lead to a drop in platelets. Platelets are also needed for blood clotting, and low levels may also lead to bleeding.
* Jaundice. This occurs when your liver isn't able to remove bilirubin — the residue of old red blood cells — from your blood. Eventually, bilirubin builds up and is deposited in your skin and the whites of your eyes, causing a yellow color. Excreted bilirubin may turn your urine dark brown and your stools a pale clay color.
* Itching. Bile salts deposited in your skin can cause intense itching.
* Hepatic encephalopathy. A liver damaged by cirrhosis has trouble removing toxins from your body — normally one of the liver's key tasks. The buildup of toxins such as ammonia — a byproduct of protein digestion — can damage your brain, leading to changes in your mental state, behavior and personality (hepatic encephalopathy). Symptoms of hepatic encephalopathy include forgetfulness, confusion and mood changes, and in advanced cases, delirium and coma.
* Weak bones (osteoporosis). Cirrhosis interferes with your liver's ability to process vitamin D and calcium, both of which are essential for bone growth and health. As a result, weak, brittle bones and bone loss are a common complication of the disease. Taking calcium and vitamin D may help prevent osteoporosis.
* Liver cancer. Cirrhosis can increase the risk of liver cancer, which occurs when malignant cells begin growing in the tissues of your liver.
* Liver failure. This occurs when extensive damage to liver cells makes it impossible for your liver to function.
When damage is so severe that liver function is seriously impaired, a liver transplant may be the only option.  (+ info)

Can someone live with Cirrhosis of the liver and Hepatitis C?


If someone has a bad liver and the doctors are saying that there is nothing else they can do and want to put that person in a hospis because they only have a short time because they're body is shutting down, could the liver just start to work again on it's own?can you get a liver transplant if your body is not doing good?
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While I would never say never, it would literally take a miracle for that to happen.  (+ info)

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