FAQ - Paraneoplastic Polyneuropathy
(Powered by Yahoo! Answers)

How many people on statins complain of muscle pain, muscle weakness, polyneuropathy, congestive heart failure?


There is a rising incidence of coronary heart failure - a rising epidemic according to the NHBLI which correlates very well with the rising use of statins.
While it is only a mathematical relationship, it appears that such relationships are replacing proper CAUSAL PROOF in medical therapy reports!
----------

both my wife and i were put on statins thinking our doc was showing go care of us but found out they are getting money for each patient on these pills, i was in so much pain i stopped taking it, i am type2 diabetic. my wife also stopped in great pain she suffers from rheumatoid arthritis and osteoporosis is on prednisolone,hope this info is what u wanted.popa  (+ info)

what does paraneoplastic syndrome mean ? Does it mean that my breast cancer cells has been active again?


What tests should I have to undergo for these findings. I am so scared. Please explain to me. Thank you.
----------

Come on, it would take so much less time to hit Wikipedia than to yahoo answers this one. http://en.wikipedia.org/wiki/Paraneoplastic_syndrome  (+ info)

What is Axonal sensorimotor peripheral polyneuropathy?


My doctor has told me I have this,is this something that is treatable?What is involved in the treatment?
----------

The peripheral nervous system can be involved in a wide range of medical disorders with various pathophysiologies (Table 1).1 It may be affected by numerous toxins, both drugs (Table 2) and industrial agents (Table 3), and by a variety of chronic infections, including human immunodeficiency virus (HIV). Furthermore, a number of apparently immune-mediated disorders result in peripheral neuropathies, including Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and multifocal motor neuropathy with conduction block syndrome (MMNCB).2 Finally, a host of hereditary polyneuropathies may cause a wide range of peripheral neuropathy syndromes (Table 4).

This diverse array of possible etiologies can make the diagnosis of peripheral neuropathies quite challenging. Nevertheless, diagnosis can be facilitated with a systematic approach that classifies the peripheral neuropathy on the basis of clinical features, taking into account the type of peripheral nerve fiber that may be involved ( ie, sensory, motor, or autonomic), the distribution or pattern of peripheral nerve-fiber involvement (ie, generalized and symmetric versus asymmetric and multifocal), and lastly, the mode of evolution (ie, acute, subacute, or chronic).


THERAPY
Specific therapies for polyneuropathy are based upon the precise etiologic diagnosis. In those disorders attributed to underlying medical conditions, management is focused on the medical disorder. For example, optimizing glycemic control in diabetic polyneuropathy will often stabilize or improve the polyneuropathy. In patients with idiopathic immune-mediated polyneuropathies, including GBS, CIDP, and MMNCB (multifocal motor neuropathy with conduction block), specific immune-modulating therapies are often recommended.2,11 For GBS, intravenous gamma globulin (IVIg), typically administered at a dosage of 400 mg/kg daily for 5 consecutive days, is initiated early in the patient's course. Alternatively, plasmapheresis may also be instituted as initial therapy. Treatment of CIDP may begin with corticosteroid therapy; however, chronic IVIg and/or plasmapheresis are usually very effective and obviate the need for long-term steroid therapy. Toxic polyneuropathies are managed by discontinuing the offending drug or removing the industrial toxin from the patient's environment. Management of hereditary polyneuropathies includes education of the affected family members regarding the nature and genetic features of the disorder and judicious screening of family members at risk.

For all patients. but particularly for those without a specific or treatable etiology, therapy focuses on supportive measures. This may include the use of various physical therapy and occupational therapy modalities including bracing and aids to ambulation. The use of an ankle-foot orthosis may be very effective in improving ambulation in a patient with foot drop. In those patients with severe sensory loss in the feet and lower extremities, careful daily foot inspection for signs of trauma and infection are essential to prevent serious infections and other complications.

In those patients who have associated pain, particularly patients with SFN, specific neuropathic pain management is instituted. Neuropathic pain typically does not respond to simple analgesics, and its potential chronicity precludes narcotic therapy as a first choice. Typically, patients with SFN and other painful polyneuropathies respond to drugs known to be effective for neuropathic pain, including tricyclic antidepressants and a variety of antiepileptic drugs and membrane stabilizers (Table 7).3,7,12 The choice for each patient must be individualized, taking into account potential side effects and drug interactions, among other factors. For patients requiring sedation due to disturbed sleep from the pain, a sedating tricyclic drug taken at bedtime, such as amitriptyline, is a good choice. However, the anticholinergic side effects of the tricyclic antidepressants make them a poor choice in those patients with prominent dysautonomia, as they are likely to worsen gastrointestinal dysmotility and bladder dysfunction. Because most of these drugs can potentially cause sedation, it is customary to begin therapy with small doses and gradually escalate as needed and tolerated. However, it is important to increase a drug to a reasonable dosage before determining its clinical efficacy. Drugs with little efficacy despite high doses should be tapered and discontinued before starting an alternative drug. On the other hand, drugs that provide some relief but are not controlling the pain adequately may be maintained in some circumstances, and another drug may be added to the regimen.  (+ info)

Just diagnosed with Chronic Inflammatory Demilinating Polyneuropathy?


I have read a lot about this on the internet. However, I am not getting any info on the pain.
I have chronice pain, left leg, hip and foot. I have pain in the rest of my body, however, the above mentioned is worse.
I am on lortabs, flexeril , neurontin and celebrex. Sometimes it is just not enough for these intense sporatic bouts of pain
Has anyone else got this and have so much pain that you can't stand it?
----------

So sorry you are in pain. I pray you get the answers you need.
The Malware above has been reported.
Blessings to you.  (+ info)

Does anyone have Chronic Inflammatory Demyelinating Polyneuropathy?


IIt's also known as Chronic Guillian Barre syndrome.It's an autoimmune disease where your immune system mistakes your nerves as foreign bodies and attacks the protective coating of myelin around them. It causes a very wide range of symptoms because it deals with the nervous system and is hard to diagnose because it can only be done after eliminating everything else. Does anybody happen to have this rare disease?
----------

  (+ info)

Does paraneoplastic phenomenon occur due to the infiltration of nerves by the tumour?


Look it up on the web....  (+ info)

Dosage for Chronic Inflammatory Demyelinating Polyneuropathy or CIDP?


CIDP is a rare chronic condition with an ample range of variations, usually involving a cocktail of drugs/ treatments tailored to each individual as effectiveness varies widely across patients, dosage associated to weight, severity, associated syndromes, etc. Please check with your neurologist; avoiding alternative treatments is advisable unless your medical team states they don't interfere with your standard treatment. It is too serious a condition to jeopardize your health due to false promises of cure. There may be ups & downs but chronic so far means "no cure". Regular exercise is recommendable, though again linked to every patient's specific features and medical supervision.

For further details you may check the GBS/CIDP Foundation International website at http://www.gbs-cidp.org. They're glad to help out.  (+ info)

I Was diagnosed with polyneuropathy and piriformis syndrome?


I am a 57 year old woman in a lot of pain. They gave me gabarten
and told me not to sit much That hard as I am an accountant

please help
----------

please can i ask were you are from just the country...
my wife has plyneuopathy and has had since 2001. i must say that it affects people in different ways. so don't be alarmed.
my wife and i are from Ireland it took allot of time for her to be diagnosed with polyneuopathy about 2years. back and forth it this hospital,seeing this Dr and that Dr. finally she was sent to pain clinic. and bingo polyneuopathy Finlay just having a name for it was great.
then followed the problems, the first years or two where not bad just allot of pain and the pins and needles, but then we seen big changes every year. we used to say at the begin of each year (god that was a bad year hope this year will be better) but who are kidding each year is worst.
well my wife is know in a powerwheel chair. she has lost her voice, and she seems to be lossing the use of her left arm.
she is on allot of medaction which seem to help but who`s too know if it is or not.
lyrica (pregabalin)
lamictal (lamotrigine)
amitripeyline
oxycontin
valium
there is allot of information on the net about polynueopathy, but i think people can get draw in to worst cases.
and think o my god im going to die or im going to loss my legs. as i said people have diffrent symtoms.im sure some people aren`t as bad as my wife but in sure there is people worse than my wife.
if your polynueopathy affects your feet i would say look after you feet well. keep them clean and dry.
as for your piriformis i found this on the net
.
Treatment usually begins with stretching exercises and massage, and the avoidance of contributary activities such as running and bicycling. Some clinicians recommend formal physical therapy, including the teaching of stretching techniques, manual massage, and strengthening of the core muscles (abs, back, etc.) to reduce strain on the piriformis muscle. Recommended stretching exercises will usually target the piriformis muscle, but may also include the hamstrings and hip muscles, in order to adequately reduce pain and increase range of motion.

Patients with piriformis syndrome may also find some pain relief from ice and heat. Ice can be helpful right when the pain starts or immediately after an activity that usually causes pain (e.g., going up stairs). The ice may be in the form of an ice pack held to the area or an individual ice cube used in combination with a massaging motion. A heating pad may be alternated with the ice for relief from the pain.

Anti-inflammatory drugs (such as ibuprofen or naproxen) and/or corticosteroid injections can be used. Occasionally surgery may be recommended. The prognosis with treatment is generally good. Custom foot orthotics also help with the treatment and prevention. By correcting a persons gait, the use of the piriformis muscle is greatly reduced allowing the muscle to relax and heal itself. Ultrasound is another option for treatment as it speeds up the healing precess.

Minimal access surgery using newly reported techniques has also proven successful in a large scale formal outcome published recently
very sorry for the very long reply. please take care.
maurice sheehy  (+ info)

What does paraneoplastic syndrome refer to?


a. the effects of substances such as hormones secreted by the tumor cells
b. severe weight loss and cachexia associated with advanced cancer
c. the decreased resistance to infection resulting from malignant tumors
d. the effects of multiple metastatic tumors
----------

It is a syndrome directly resulting from a malignant neoplasm, but not resulting from the presence of tumor cells in the affected parts.  (+ info)

I have to go get a CT scan of my chest on Monday, What exactly is Paraneoplastic Syndrome? Is that like a Pl


Is that like a bad Flu bug?
----------

This generally refers to neurologic diseases that occur in association with cancer but are not directrly caused by the cancer or its metastastisis. They are relatively rare.

This is a nice article:
http://mayoclinic.com/health/paraneoplastic-syndromes/DS00840  (+ info)

1  2  3  4  5  

Leave a message about 'Paraneoplastic Polyneuropathy'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.