FAQ - Polyendocrinopathies, Autoimmune
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What are the differences between celiac disease and autoimmune hepatitis?


The high liver enzymes levels (3 folds of one of them) and high total bilirubin (2.8) is good indicators to say it is autoimmune, if we can not do the tests for the celiac disease
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Hi Im Chris, Both diseases are autoimmune diseases. in autoimmune diseases the bodys own cells become overactive and start attacking either one part of the body (as is the case pretty much in these, with autoimmune hepatitis it is the liver, in Celiac it is an intolarance to foods that are strachy, sugared, etc). In other disease like Lupus, MS, and others they are more widespread and attack the entire body or more bodily functions or systems.

I personally have Lupus, Sjgrens and Autoimmune Hepatitis.
I Know a little about Celiac disease so I did some research, so I will let you know about how they diagnose that first.

Celiac disease is a digestive disease that damages the small intestine and interferes with absorption of nutrients from food. People who have celiac disease cannot tolerate a protein called gluten, found in wheat, rye, and barley. Gluten is found mainly in foods but may also be found in products we use every day, such as stamp and envelope adhesive, medicines, and vitamins. to diagnose it they do several things.

How is celiac disease diagnosed?
Recognizing celiac disease can be difficult because some of its symptoms are similar to those of other diseases. In fact, sometimes celiac disease is confused with irritable bowel syndrome, iron-deficiency anemia caused by menstrual blood loss, Crohn’s disease, diverticulitis, intestinal infections, and chronic fatigue syndrome. As a result, celiac disease is commonly underdiagnosed or misdiagnosed.

Recently, researchers discovered that people with celiac disease have higher than normal levels of certain autoantibodies in their blood. Antibodies are protective proteins produced by the immune system in response to substances that the body perceives to be threatening. Autoantibodies are proteins that react against the body’s own molecules or tissues. To diagnose celiac disease, physicians will usually test blood to measure levels of

Immunoglobulin A (IgA)
anti-tissue transglutaminase (tTGA)
IgA anti-endomysium antibodies (AEA)
Before being tested, one should continue to eat a regular diet that includes foods with gluten, such as breads and pastas. If a person stops eating foods with gluten before being tested, the results may be negative for celiac disease even if celiac disease is actually present.

If the tests and symptoms suggest celiac disease, the doctor will perform a small bowel biopsy. During the biopsy, the doctor removes a tiny piece of tissue from the small intestine to check for damage to the villi. To obtain the tissue sample, the doctor eases a long, thin tube called an endoscope through the mouth and stomach into the small intestine. Using instruments passed through the endoscope, the doctor then takes the sample.

What is the treatment?
The only treatment for celiac disease is to follow a gluten-free diet. When a person is first diagnosed with celiac disease, the doctor usually will ask the person to work with a dietitian on a gluten-free diet plan. A dietitian is a health care professional who specializes in food and nutrition. Someone with celiac disease can learn from a dietitian how to read ingredient lists and identify foods that contain gluten in order to make informed decisions at the grocery store and when eating out.

For most people, following this diet will stop symptoms, heal existing intestinal damage, and prevent further damage. Improvements begin within days of starting the diet. The small intestine is usually completely healed in 3 to 6 months in children and younger adults and within 2 years for older adults. Healed means a person now has villi that can absorb nutrients from food into the bloodstream.

In order to stay well, people with celiac disease must avoid gluten for the rest of their lives. Eating any gluten, no matter how small an amount, can damage the small intestine. The damage will occur in anyone with the disease, including people without noticeable symptoms. Depending on a person’s age at diagnosis, some problems will not improve, such as delayed growth and tooth discoloration.

OK That is the Symptoms, diagnosis and treatment after the diagnosis. Onto The autoimmune Hepatitis, I will use personal experience and some information from a website.

Autoimmune Hepatitis has nothing to do with Hepatitis A, B, or C. It is not contagious in any way shape or form. It can stand alone as it's own autoimmune disease or can be triggered by another. Usually either Sjogren's or Lupus (SLE). Usually Sjogren's. It can also be called Lupoid Hepatitis.

The symptoms most common are an extended painful upper abdomen, jaundice, Enlarged Liver, Itchiness, Fatigue, joint pain, skin rashes, nausea, vomiting, loss of appitite, dark urine, pale or grey stools.

I remeber looking 5 months pregnant though I didnt eat.

There are several steps of testing. First are abnormal basic Liver function tests AST, ALT, Billirubin, Sometimes a Positive ANA (Antinuclear Antibody, also found in other autoimmunes like Lupus, sjogrens, and others), a positive Anti-Smooth Muscle Test Or its inititls (sp) SMA. The pattern and level of these test help distinquish which disease may be going on. In addition you more than likely will have a liver biopsy. I had one. I had no problems. I had it, woke up was on side, and wanted to leave.. they wanted me to stay. I stayed for awhile. But not all people wake up as well as I do from surgery. I was a bit sore.

Right now there are two mainstream treatments, I do not use either one, both do not work on me. Those treatments are Prednison (a class of medical steroids), and Imuran (an Immunosuppresent, used for transplant paitents, and other sutoimmune diseases). In the last several years, They have found that the medication first used for gallstones and galbladder disease called Actigall is very effective along with the natural herb Milk Thisle. Those are what my Rhuemotologists use on me. She swears by both. I was getting very close to a transplant list. I did need some IV chemo, but with that and those two other therapies I am in total remisson. In fact with proper care 7 out of 10 paitents will go into remisson. Many may still have mild attacks, mine come and go.

Both disease are not desirable. No autoimmune disease is, but with proper care and following your doctors orders both can be controlled. I do co-own an autoimmune support group, we do a lot of Lupus, but we are a mixed bag of everything, mainly females but male and female.

Good luck
Any questions email me at [email protected]
Im good for the autoimmune Hepatitis  (+ info)

what do you think of ozone therapy to treat autoimmune disorders?


Is it really safe? From what I read, ozone therapy is injecting the ozone which is a toxin into the bloodstream. That shakes up the body to fight what caused the autoimmune disorder. Is this right? Can it harm someone more to try it?
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Ozone is oxygen in its most active state and is an extremely potent oxidant that has been shown to posses broad spectrum antimicrobial activity. Ozone also has indirect actions on our immune systems. It stimulates Th1 cytokines while at the same time down regulates Th2 cytokines.
Ozone therapy is a means to deliver oxygen to the body’s cells and has been proven to treat a variety of illnesses such as HIV, cancer cells, autoimmune disease, arthritis and pain, infection, colds and flu. This is important because, unlike healthy cells that love oxygen, disease causing viruses, bacteria, parasites and fungi are almost all anaerobic, meaning that they use sugar to survive instead of oxygen and cannot survive in an oxygenated environment

Major Autohemotherapy (MAHT) with O3 is used for general immunoactivation in patients with a low immune status and/or immune deficit. It thus brings about an immuno-modulator effect the lymphocyte subpopulations and is very effective in treatment of autoimmune disorders- multiple sclerosis, rheumatoid arthritis etc.

Routes of administratin of Ozone are -
[1] Intravenous therapy
[2] Vaginal or rectal insufflations
[3] Autohaemotherapy
[4] External limb bagging
[5] Ozonated olive oil

The oxidative effect of ozone can also be harmful. To prevent such effects, it is best to take a good anti-oxidant combination for 7 days before starting intravenous ozone therapy.

Ozone therapy is contraindicated in the following: Recent heart attack, pregnancy, recent internal bleeding, hyperthyroidism, thrombopaenia and alcoholic intoxication.

Ref site below for more details -  (+ info)

How do you boost your immune system to fight off a cold, allergy, or flu if you have an autoimmune disease?


Am writing a school paper about multiple sclerosis, so if you can relate your answer to MS, that would be awesome. I am very puzzled: The immune system is misidentifying myelin as a foreign invader, so if you "feed" nutrition to the immune system to fight off a virus or pollen, for example, doesn't it also increase the autoimmune response that destroys the myelin sheath?
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i think you should really do a research paper on the credibility of the theory of autoimmune diseases. are they really the cause of the immune system fighting the body?

autoimmune diseases are kind of controversial.  (+ info)

Diet and autoimmune diseases: how does one affect the others?


What are foods that one should avoid if one has an autoimmune disease such as arthritis, lupus or fibromyalgia?

What foods should be eaten to reduce symptoms of body pains and general fatigue?
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I have Fibromyalgia,chronic epstein barr,arthritis,and dercums disease. I tried lyrica and some other medicines but none have helped...one dr had me on such a high dose of lyrica that I had to remind myself to swallow or I would be drooling...NO good. Dietary is the way to go ...I know if you are like me you want to feel better RIGHT away but that doesn't happen...have you tried all natural or the five or less ingredients diet(meaning almost anything with 5 or less ingredients are easier on your digestion and liver which is affected in many auto immune dieseases)rhumatologists and a few other drs have told me to try to follow atkins diet orsomething close to it like mediterean or even south beach ...because carbohydrates increase inflamation and that means more pain basically...even if you don't need to lose weight you can still follow a version of the atkins just using carbs according to how you feel(and if you have the money try to stay organic with everything because your system does not need to have to process chemicals to make you feel worse again)...BUT definitely run this by your dr first ok.feel better and sorry you have an autoimmune disease.  (+ info)

Ladies with autoimmune diseases, are you afraid of passing on the wrong immunity genes to your baby?


I have celiac disease and Hashimoto's thyroiditis, the latter discovered during pregnancy, and I'm somewhat worried that my baby may inherit either them or just a background for some more autoimmune problems. Would you feel guilty if your child did inherit any 'bad gene' from you?
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Oh yes, terrified! I have 4 autoimmune diseases and have a 7 year old son. Thankfully, I only had one or two when I had him. So far, he's doing well and only has odd allergies (I believe it's related).

Hormones affect AI diseases. Pregnancy can actually stop AI symptoms.

Yes, I'd feel guilty, but there's so much that we don't know... I wish you luck.  (+ info)

Which statement best describes the relationship between immune disorders and autoimmune diseases?


A.Immune disorders include autoimmune diseases, in which the immune system attacks the body’s own cells.
B.Immune disorders are a kind of autoimmune disease in which the immune system attacks the body’s own cells.
C.In both immune disorders and autoimmune diseases, the immune system attacks the body’s own cells.
D.There is no relationship between immune disorders and autoimmune diseases.
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probably A  (+ info)

What is the chance I have an autoimmune disease?


I have elevated ANA, and my doctor ordered a myriad of other tests, only some of which came back as of today. The ones that came back where Complement (C3c) and Complement (C4). They were both normal.

My doctors thinks I have some sort of autoimmune disease, probably lupus. I'm just wondering before the rest of the tests came back what my chances were of having a disorder with the increased ANA but normal complement tests.

Anything help you could give me would be greatly appreciated. Thanks.
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What are your symptoms?

I have been diagnosed with Fibromyalgia, Rheumatoid Arthritis and Osteoarthritis. And it is not much fun ..Even on the good days.  (+ info)

What's the name of the autoimmune skin condition that makes your skin welt with just a little scratch?


When you even scratch yourself lightly (like to scratch a light itch) Your skin welts up for 20 minutes or more. It's an autoimmune condition. First correct answer will get the 10 pts. I can't remember the name of it, and I want to research it more. (my brother has it)Thanks!
dermatographia is what i was thinking of Thankyou SOO much!!!
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Are you talking about dermatographia? I've seen it before when I worked in dermatology - you can "write" on the skin with a fingernail and the skin will flare up so you can read what you wrote.  (+ info)

Chances of a baby having an autoimmune disease if BOTH parents have one?


My boyfriend and I both have autoimmune diseases, if at some point we ever decided to have a child together how likely would the baby be to also have an autoimmune disease? By the way I have SLE and he has alopecia.
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Since they're different, probably a 1 in 4 chance for the baby to get either one.  (+ info)

Is it possible for Autoimmune Disease to ever go away?


I started getting hives back in January. Whenever I eat certain foods, I get extremely bad hives about 5 hours later or more. I was diagnosed with an Autoimmune Disease. I'm only 25, and this came out of nowhere. I was told by my allergist that a good percentage of people with this, it goes away on average, 10 - 12 months later. Aside from that, does anybody know if this is going to last forever?
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