FAQ - fibromuscular dysplasia
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fibromuscular dysplasia?


i know that people who have carotid FMD have a higher risk of develping an intracranial aneurysm, but what are the odds of developing one if a patient refuses an angioplasty?
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Patients with impaired carotid arteries may have nonspecific complaints including dizziness, temporary blurring or loss of vision, tinnitus (ringing or buzzing in the ears), vertigo (feeling as if the room was spinning around you), neck pain, and or chronic headaches. However, a person with severe FMD may have neurological symptoms involving the facial muscles (drooping of the face, for example), stroke, or transient ischemic attack. People with carotid FMD have a higher risk for intracranial aneurysms (abnormal dilations of the arteries in the brain). An intracranial hemorrhage (bleeding in the brain) may occur if an aneurysm ruptures

Most individuals should take an antiplatelet agent daily (i.e., aspirin). Aspirin therapy (81mg a day or 100mg every other day) is now recommended for stroke prevention in women under 65 as long as the benefits outweigh the risks. All patients who use tobacco should be encouraged to quit.

Exact odds are not given but, it is evident that without treatment the odds go up. If you are concerned contact your or your family members Cardiologist & discuss the odds pertaining to your/their case. Angioplasty is the only treatment listed, so if advised by the doctor....hopefully, the patient would change their mind. Good luck!

http://www.fmdsa.org/about_fmd.html
http://www.ninds.nih.gov/disorders/fibromuscular_dysplasia/fibromuscular_dysplasia.htm  (+ info)

What does it mean in laymens terms when someone dies of "fibromuscular dysplasia of the small coronary artery?


Please give me some source material as well.
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Fibromuscular dysplasia is a disease that involves narrowing of blood vessels (arteries). It is essentially due to changes in the blood vessels wall, narrowing of the blood vessels therefore less blood is able to travel to the tissue (eg. heart). If the narrowing is severe enough, then the blood vessel (artery) will not be able to provide enough nutrients to the tissue (eg. heart) and this will lead to the death of the tissue, If heart tissue is involved, we call this a heart attack (myocardial infarction). Heart attacks may just damage the tissue but it can certainly lead to death. The blood vessels of the heart are called the coronary arteries.

Fibromuscular dysplasia is not related to a disease called atherosclerosis which is the most common cause of heart attacks. Fibromuscular dysplasia is much rarer. Fibromuscular dysplasia usually involves the arteries that supply the kidneys and it is very rare for it to involve the coronary arteries. It can of course affect any artery in the body. I hope this answers your question and if not let me know.

Rescources
http://www.mayoclinic.com/health/fibromuscular-dysplasia/DS01101
http://en.wikipedia.org/wiki/Fibromuscular_dysplasia
http://www.fmdsa.org/
http://www.ninds.nih.gov/disorders/fibromuscular_dysplasia/fibromuscular_dysplasia.htm  (+ info)

Does anyone have Fibromuscular dysplasia?


Does anyone (or anyone you know) have Fibromuscular dysplasia,if so how does it effect your life.Any info would be great.
I did find a link http://en.wikipedia.org/wiki/Fibromuscular_dysplasia but would like to hear personal experiances.
Thank you :)
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I discovered I had FMD in 2003. At that time very little was known about the disease; this is still true to some degree. Although great strides in research have been made, it is unfortunate that there are still very few physicians that truly and adequately know how to treat it.
FMD can effect every patient differently, often depending on the area of involvement (ie: renal, carotid, vertebral, mesenteric ect...) , although there are some symptoms that considered common in the patient communities. These include chronic headaches, dizziness, and high blood pressure. Some associated, possible effects resulting from the cause of FMD include aneurysm , TIA (transient ischemic attack), arterial dissection and stroke. Some people might continue their whole life being asymptomatic (not exhibiting any or very few symptoms); having found FMD incidentally during diagnostic testing like MR or CT for something else.

For others (including myself) a string of progression can be seen. (In hindsight) I started with the development of high blood pressure in my early 30's. From there, I began to have abdominal and flank pain in my right side and a bruit over my renal artery (a swishing sound in the vessels) was heard by my dr. During this initial phase, I had a "hypertensive crisis" and my blood pressure was extremely high. After some diagnostics (MRA and ultrasound), stenosis (vessel occlusion) was identified and I underwent my first balloon angioplasty... My second procedure came 6 months later and there was occlusion in both right and left sides of my renal arteries this time.

Since the initial diagnosis, (in my particular case) I've had several TIA's, a small stroke, and constant and chronic pain in my head, abdomen and neck. Along with that are bouts of dizziness and feelings similar to severe anxiety that come if my bp starts to spike. Since the development of stenosis in the arteries that supply blood to my stomach, I have a difficult time eating and chronic constipation are common.

As I said, sort of like a cold, the degree of symptoms can vary from person to person. My case is considered more complicated than most. Some may have a severe event, like dissection before their FMD is diagnosed and some may go their whole lives without exhibiting any symptoms.

Hope that helps.  (+ info)

Nayone have fibromuscular dysplasia? I amd diagnoed with it?


Can you she]are some information about that.
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I dont have FMD but I am familiar with the disease. I work in a vascular surgery office so we see some of these patients. FMD can affect your arteries-especially your renal arteries to your kidneys and your internal carotid arteries that feed your brain. Health care professionls call it the "string of beads appearance" your arteries actually become narrowed and then normal and then narrowed again so blood flow is restricted through these arteries. Usually this disease affects young(30-40's) women. I would ask your doctor if you should see a vascular doctor of have some tests i.e. ultrasounds, angiograms to check your blood vessels for any of these narrowings. If you have high blood pressure or are having any stroke like symptoms I would definately go to the doctor.  (+ info)

What happens when the cervical dysplasia is gone but the high risk hpv is still present?


I was diagnosed with low-grade cervical dysplasia a while ago and following my most recent test I was told that I no longer had the dysplasia but the high-risk hpv that caused it was still there... Does this mean that cervical dysplasia could come back? And is it possible that the hpv could ever go away?
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Yes, if you still have HPV present, then you could have a recurrence of cervical dysplasia. This mean you need to have regular Pap smears to monitor your progress.

Most women clear their infection eventually. But some women's infections persist indefinitely. I don't know which category you're in, but you will have to take a wait-and-see approach. In the mean time, you should take good care of yourself. Don't smoke (smoking is linked to greater risk of dysplasias), eat healthy and exercise so your otherall health and immune system are working well.  (+ info)

What is the difference between hyperplasia and dysplasia- and can anyone give me a reference for it?


I can't seem to find a book or journal article that specifically defines the difference between dysplasia and hyperplasia- any help would be much appreciated!
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Hyperplasia is a general term referring to the proliferation of cells within an organ or tissue beyond that which is ordinarily seen

Dysplasia is a term used in pathology to refer to an abnormality of development.

Hyperplasia = excessive normal cells which are benign.
Dysplasia = excessive abnormal cells which can become malignant.  (+ info)

How long does it take for moderate cervical dysplasia to turn into cancer?


I have moderate cervical dysplasia and need a LEEP procedure done. I am a single mother of 4 and can't come up with the $500 that our local clinic is charging for the procedure. How long can I safely wait before this gets worse and turns into cancer?
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You really should get treatment, but In also honesty, it's pretty safe to wait.

Moderate dysplasia only has about a 5% chance of becoming cancer ever, and usually it takes about 10 years for dysplasia to become cancer. Moderate dysplasia can progress to severe dyplasia quite quickly, but left untreated for a year, severe dysplasia only has about a 3% change of becoming cancer.

Doctors often wait to treat moderate dyplasia in young women (like under 20) because many fight it off on their own. Also in pregnant women, most doctors would not treat moderate dysplasia until after the baby is born.

They did this clinical trial at Johns Hopkins where they followed women with severe dysplasia for 15 weeks without treatment. They figured 15 weeks was a safe period to just observe and do nothing.

So, save up because eventually you are probably going to have to treat this. But I'd say you can wait several months without worries.  (+ info)

How often after being cleared of cervical dysplasia should I be getting pap smears?


I have had cervical dysplasia twice. Once when I was 22 and again when I was 26. After this last time I had cryosurgery and was cleared of the dysplasia. I am curious about how often I need to be going back for pap smears. I heard that I should be going back more than just once a year but my doctor did not mention when I need to return.
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It depends on how severe your dysplasia was. Different classes advance at different levels. Most people with cervical dysplasia get pap smears once or twice a year, but severe dysplasia may have to be watched more closely, even quarterly or monthly. Once you have 2-3 clear pap smears, you're fine to go once a year. Call your doctor to find out when you should go back.  (+ info)

What questions should I ask my doctor about severe dysplasia?


I have had a biopsy done which had shown that I have severe dysplasia and will be getting a LEEP done on Tuesday. I don't have children yet but want to. I know more about dysplasia and other things regarding it because I have been researching it but I want to know what questions I should ask my doctor.
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I had a leep done last september and it went surprisingly well. Ask about:

How long you need to wait before you can have sex, etc. The longer the better, my doctor told me 2 weeks and I have since been told that that was not long enough.

Ask what you can expect as far as the healing process, I was very surprised when I started passing clots, which is normal, but my doc didn't tell me about it so I was pretty freaked out when it started happening.

Ask what to expect as far as bleeding after sex, I am still experiencing bleeding occasionally and it can be very frustrating.

Ask when you will be hearing about the test results of the removed tissue - it usually only takes a couple days (the tests will confirm that the abnormal cells were not cancerous and will also indicate whether all the abnormal cells were removed).

You may also want to ask about complications after the surgery, like incomplete removal of cells, narrowing of the cervical opening, and excessive bleeding and scar tissue.

Ask any other questions that you can think of about any other things that you are concerned about. Try making a list so that you don't miss anything; you'll probably be nervous and you don't want to go home wondering about the things you forgot to ask. The procedure took my doctor less than ten minutes, and my cramping during healing was minimal. Ask your doctor what he recommends to take for pain. Make sure you have tons of pads (the always infinity ones are the best, they're really thin and light and super absorbent. You can expect to bleed for two weeks or more.

I hope this helps, good luck!  (+ info)

What would dysplasia have to do with teeth/orthodontists?


I was reading my orthodontic file and I think it said something about dysplasia... Most of the words were really confusing and I didn't understand them, the only one I remembered was dysplasia (I think). What is dysplasia, and what would it have to do with my teeth?
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Dysplasia (from Greek, roughly: "bad form") is a term used in pathology to refer to an abnormality in maturation of cells within a tissue. This generally consists of an expansion of immature cells, with a corresponding decrease in the number and location of mature cells. Dysplasia is often indicative of an early neoplastic process. The term dysplasia is typically used when the cellular abnormality is restricted to the originating tissue, as in the case of an early, in-situ neoplasm. For example, epithelial dysplasia of the cervix (cervical intraepithelial neoplasia - a disorder commonly detected by an abnormal pap smear) consists of an increased population of immature (basal-like) cells which are restricted to the mucosal surface, and have not invaded through the basement membrane to the deeper soft tissues. Myelodysplastic syndromes, or dysplasia of blood-forming cells, show increased numbers of immature cells in the bone marrow, and a decrease in mature, functional cells in the blood.  (+ info)

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