FAQ - leukemia, monocytic, acute
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Is Acute Monocytic Leukemia the same thing as Acute Myeloblasitc Leukemia?


A friend of mine's dad was diagnosed with Acute Monocytic Leukemia (AML) today and I've done some research on it. http://www.orpha.net/data/patho/Pro/en/AcuteMonoblasticLeukemia-FRenPro8561.pdf has an article on ACM (I found it through Google) but it also lists Acute Myeloblasitc Leukemia as ACM on the same page. Does anyone know if it is the same thing or not?

Thanks!
Oops, I mean AML. I have no idea where I got ACM from...

And this question is now answered! I'd close it or select the anser as the best one, but I'm not that great with computers and I don't know how...
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AML has several different generally accepted sub-tupes:

The eight FAB subtypes are:
M0 minimally differentiated acute myeloblastic leukemia
M1 (acute myeloblastic leukemia, without maturation)
M2 (acute myeloblastic leukemia, with granulocytic maturation)
M3 (promyelocytic), or acute promyelocytic leukemia (APL)
M4 (acute myelomonocytic leukemia)
M4eo (myelomonocytic together with bone marrow eosinophilia)
M5 acute monoblastic leukemia (M5a) or acute monocytic leukemia (M5b)
M6 (acute erythroid leukemias), including erythroleukemia (M6a) and very rare pure erythroblastic leukemia (M6b)
M7 (acute megakaryoblastic leukemia)

The treatment is similar for most of them. M3 is quite different though. And I am not sure about the M6 group.  (+ info)

What is acute lymphocytic leukemia in a chronic stage?


A friend was recently diagnosed with acute lymphocytic leukemia but said that hopefully it'll be in a chronic stage. I have no idea what any of this means. I went online and was doing a little research but it said it effected mostly older people, and he's only twenty. I couldn't find anything on what treatment entails or what chronic stage means. Anyone deal with this on a first hand experience? Is a chronic stage good?
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Acute Lymphocytic Leukemia (ALL)

There are four major types of leukemia. ALL is the most common type of leukemia diagnosed in children, and the least common type diagnosed in adults. About 5,200 people are diagnosed with ALL each year. Children account for two-thirds of these cases. In general, children with ALL have a better prognosis than adults. Most children with ALL can be cured of this cancer.
Symptoms of ALL include fatigue, pale skin, recurrent infections, bone pain, bruising, and small red spots under the skin. Doctors use various tests, including blood counts and bone marrow biopsies, to diagnose ALL.ALL is treated with chemotherapy and, sometimes, radiation. Children receive different types of chemotherapy regimens than adults. Patients with advanced cancer that has not responded to these treatments may need a stem cell transplant.  (+ info)

What is the best treatment for Acute Lymphocitic Leukemia?


What is the best treatment for Acute Lymphocitic Leukemia? Can you please give me the hospital names and the location where the treatment could be done?
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Combination chemotherapy. St. Jude Children's Research Hospital has reported a 5-year-survival rate of more than 90 percent for acute lymphoblastic leukemia (ALL).  (+ info)

What is type b acute lymphoblastic leukemia?


I just heard recently that my cousin has type b acute lymphoblastic leukemia and I was just wondering what exactly it is? what the symptoms are? what does it mean by type b? and can it be treated or can it kill you no matter what?

Thanks in advance.
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Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Other names for ALL are acute lymphocytic leukemia and acute lymphoid leukemia. Leukemia affects either B lymphocytes( a type of white blood cell) or T lymphocytes (another type of white blood cell). Immunophenotyping is used to find out if the patient's leukemia cells are B cells or T cells. Most people with ALL have the B-cell type or "type B". Immunophenotyping is a procedure that is used to identify a specific type of cell in a sample of blood, marrow or lymph node cells. This procedure can be important in helping to decide on the best treatment for your cousin.

The symptoms are: Aches in arms, legs & back, bruising for no apparent reason, enlarged lymph nodes, a low-grade fever without obvious cause, headaches, pale skin, pinhead-size red spots under the skin (petechiae, pronounced puh-TEE-kee-ee) (this is bleeding), prolonged bleeding from minor cuts and scrapes, shortness of breath during physical activity, fatigue and vomiting. But ALL can't be diagnosed by these symptoms alone because they're shared by other conditions as well.

I don't know how old your cousin is but ALL is the most common type of leukemia in children under the age of 15 although it can occur at any age. Most children who have had ALL have been successfully treated and cured.

In case you're ready to ask "How did he get this?" Research is still ongoing to pinpoint the precise genetic changes that cause a normal cell to become cancerous. And ALL starts with a change to a single cell in the bone marrow. The cause and the risk factors haven't been determined yet.  (+ info)

How long does one live if diagnosed to have acute leukemia?


My friend has been diagnosed to have acute leukemia. He was advised to undergo chemotherapy. I am wondering, what is the survival rate for this kind of disease? Please advise.
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Acute lymphocytic leukemia (ALL): 64.6 percent survival rate
Acute myelogenous leukemia (AML): 19.8 percent survival rate  (+ info)

How Long Can A person Over the Age of 65 Live for with Acute Leukemia?


a few days ago we found out my gramps who is age 83 has acute leukemia , right now hes staying overnight at the hospital getting treatment and chemo....the first night (sept. 10)the docters said he might not make it...but my grampa is strong and he proved them wrong because today is thursay sept. 13 and hes alive...and it looks like hes getting better cuz the color of his skin is comin back to normal and his brusing is getting better...docters said that anyone 65 years and older have no chance for a cure and they always give them impression like he's gonna die (he is 83)...Is it possible for him to love longer then expected? like a few more years? or even a few more months?
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Anything's possible. Just pray that he's a fighter! If he wants to live longer, he will. Good luck to you and him.  (+ info)

what is the life expectancy for a 76 year old with acute leukemia?


My grandmother was recently diagonosed with acute leukemia...how long/what are the surviaval rates can she be expected to live?
shes a pretty active person...takes a weekly aerobics class, active outside, cooks, eats right. in pretty good shape.
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Sorry to hear about your grandmother.

While there are no hard and fast rules, you will get more specific answers to this question if you know whether she has
ALL (acute lymphoblastic leukemia) compared with AML (acute myelogenous leukemia). In older people, ALL usually is the last stage of CLL (the chronic form), so she most likely has AML. You should expect that her survival could be as short as a few months. However, it is totally dependent on the subtype of AML. Some leukemias now are almost uniformly put in remission by drugs like Gleevec and 2-CDA, but these have very specific uses.

I've included a website here which should answer all of your questions, but try to find out the specific type of leukemia before you look at it.

Best of luck and health to you both.  (+ info)

a young child is diagnosed with acute lymphocytic leukemia why is the infection a problem when her WBC count?


young child is diagnosed as having acute lymphocytic leukemia. Her parents cannot understand why infection is a major problem for Janie when her WBC count is so high. Can you provide an explanation for Janie’s parents?
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Without getting too typical, the type of circulation white cell associated with the disease and where it gets it's name is actually lymphoblastic leukemia. The predominant cell is an immature type of white cell. It is a precursor to the lymphocyte. Although their number is high their function is abnormal. The cell is so busy multiplying that it can not mature and function like a mature white cell would.

The other aspect to that is due to it's increased number in the bone marrow which is where the problem lies, the other white cells that are needed for infections are also produced. They get squeezed out in a sense and so their numbers (the good white cells) can go down.  (+ info)

What is the difference between acute leukemia and chronic leukemia?


If can also include a description on AML, CML, ALL, CLL leukemia
This is for my holiday homework.
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Go to webmd.com  (+ info)

What happens in the blood in a patient with acute lymphocytic leukemia?


I understand the basics of leukemia. I know it happens in the bone marrow and it affects the genes and cell structures of red or white blood cells and/or platelets.

But how exactly does a person die from leukemia? Is it safe to assume that the body runs out of oxygen because the red blood cells become too abnormal to carry oxygen around the body?
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"Deb" is mostly right - but liver and kidney function problems are not as common as bone marrow failure. It is not true that the body runs out of oxygen because the red blood cells become too abnormal to carry oxygen. The red cells can still transport oxygen in acute leukemia patients

I can explain this simply for you.
The immature malignant leukemia cells reproduce without control and crowd out the normal blood cell production in the bone marrow - so red cells - platelets - and the various types of normal infection fighting white cells - cannot be produced. It's like weeds overgowing in a garden and choking out the good plants.

Roughly 2/3's of our patients die from infections because they don't have normal bacterial and fungal fighting white blood cells. We can't transfuse normal white cells effectively.

About 1/3 of patients with acute leukemia die from bleeding due to low platelets. We can transfuse platelets, but it's hard to keep up when people make none of their own.

Oxygen transport is not usually the problem - except for the acute bleeds at the end. We can transfuse red blood cells effectively.

So why can we transfuse red cells so much more effectively than platelets or white blood cells? Normal red cells last some 120 days. Platelets in healthy people last maybe 10 days at best - though transfused platelets usually only last a day or two. Bacteria and fungal infection fighting neutrophils (white blood cells) last a matter of hours. They need to be made daily by the bone marrow. It's difficult to harvest enough normal white cells from donors to transfuse and make a significant difference to help patients.

Bottom line - infections end the lives of most leukemia patients - bacterial, fungal, viral, or all of the above.  (+ info)

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