What would cause low grade liposarcoma to upgrade to high grade liposarcoma?

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I would like to know as I get them, quite often, and I want to keep aware.
Jamie - While it is possible for a low grade liposarcoma to "upgrade" to a high grade tumor, it is very rare, and does not truly happen very often. Most low grade tumors remain low grade. What many do not know is that a tumor may initially have both areas of high and low grade present at the same time. If the tissue removed and examined by the pathologist under the microscope is low grade, there may be other tumor areas not sampled where it is high grade so that thereafter the hidden high grade part then grows and gives a more malignant diagnosis when later examined. Tumors are cells often growing in a haphazard way. At times, low grade cells may irregularly divide and form more malignant high grade cells. Patients with low grade tumor diagnoses need to be carefully observed after initial treatment(s), and hopefully will not develop high grade changes in any tumor that might still be left behind. The outlook must be guarded and hopeful.  (+ info)

How common is liposarcoma of the thigh?

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How many people does it affect? Do you know if it is possible to have a huge hard fat tumor in the thigh for a decade and it not be cancerous?
Check out wikipedia for info on liposarcoma and related links. You might stumble across what your looking for.

http://en.wikipedia.org/wiki/Liposarcoma  (+ info)

Because of liposarcoma, my quadriceps were removed and my knee hurts all the time. Can anyone help. ?

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Surgery was 10 years ago. I am still in constant pain and find that movement is getting worse because of pain in the knee. Results of tests indicate that there is nothing substantially wrong with the knee. I have seen many specialists, including sports medicine doctors, and no one can help. In the meantime, there is less and less movement possible because of the pain. Also, I have moderate lymphodema. Has anyone experienced this situation? Does anyone have a solution?
There are several online sarcoma support groups that may be able to offer you suggestions or ideas to take care of your pain.

ACOR: The liposarcoma (cancer) Online Support Group
http://listserv.acor.org/archives/l-sarcoma.html

Sarcoma Alliance
http://www.sarcomaalliance.com/anyboard9/forum/index.html

ACOR: The General Sarcoma (Cancer) Online Support Group
http://listserv.acor.org/archives/sarcoma.html

Livestrong: Cancer Survivors and Chronic Pain
http://www.livestrong.org/site/c.khLXK1PxHmF/b.2660619/

Good luck to you. Hope you can find answers soon.  (+ info)

mild joint effusion on the knee, myxoid degeneration on the meniscus, anterior wedging on the spine?

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I was reading some papers from my doctor visit and it said i have these conditions but i don't really know what they mean. Cant anyone who does know please help me?
I have a joint effusion on my right knee. I was on a car ferry, got my leg caught between the bumper of my car and the car in front and in a panic, pulled it! Since then I have this effusion, which means I am leaking synovial fluid from the joint into the exterior knee tissue. Year later they wanted to 'drain' it but I refused and have lived with it since. Their is some argument that once the joint is exposed, even to a injection, you risk infection, so I refused the needle drainage. Therefore I can but assume at some point you too have had a accident, damaged the knee, which has now lead to the effusion and meniscus degeneration. As for the spine problem, you do not stat what part of the spine???? Likewise this can be age related. Best of Luck  (+ info)

If you had myxoid lyposarcoma can you donate blood?

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I lost my leg to cancer 8 years ago. Does anyone know if I can donate blood
I think you should be able to do that, but check with the local blood donation service please.  (+ info)

Abdominal Liposarcoma...anyone know anyone who survived it, had it, or how long one can live with it?

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My friend's hubby has it and has had 3 ops and lost a kidney already. Can one live with it, how long?
3 ops in 2 years, age 64
3 ops in 2 years, age 64
3 operations and losing a kidney doesn't sound very good - but over what time period?
Sarcomas have different grades as well as different stages.
High grade sarcomas usually progress faster than low grade disease.
Liposarcomas also have at least four different histologic types.
This sounds like advanced stage disease, but we don't know the details.
Is there liver involvement? Are there lung metastases?
How much weight has he lost? What is his age and overall health? How bulky is the residual tumor? How fast does it appear to be progressing? All of these factors are important.

People often push us to make predictions, and we usually wind up being wrong since we can only use averages or quote ranges of survival times that have been observed for other people. Few people fall right at the average in survival time. We don't see many abdominal sarcomas in oncology since it is fairly rare. Each person is different.

The best person to guess is the oncologist who knows the entire case, and he or she will not want to make guesses. Often oncologists are pushed repeatedly to guess. We simply do not know. No one can know the precise future in this case.

Also, the person to be asking this question is the patient and his family. There are privacy issues involved. Doctors must respect the patient's wishes as far as releasing any medical information - even predictions or guesses.

Here's a fairly good internet link for your review.
http://emedicine.medscape.com/article/391272-overview
There are about 9500 soft tissue sarcomas each year in the U.S.
About 1 in 7 is a liposarcoma, and only a fraction of these are abdominal,
so there might be 1000 cases per year in the entire USA.
That compares with 184,000 breast cancers and 215,000 lung cancer cases out of a total of 1,437,000 cancer cases per year (excluding skin cancers).

Bottom line - this situation is not very common.  (+ info)

Abdominal Liposarcoma...anyone know anyone who survived it, had it, or how long one can live?

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My friend's hubby(age 64) has it and has had 3 ops in 2 years and lost a kidney and spleen and had a stomach ressection.
No liver involvement.
No lung metastases.
He's really skinny.

He thinks he was misdiagnosed 4 years ago after lots of tests.

Can one live with it, about how long?
Any sarcoma diagnosis requires the expertise of a sarcoma specialist. Hopefully your friends husband is being treated at a sarcoma center?

Survival from this type of sarcoma will depend on the patients age, overall health, type and location of tumor, grade (low or highly aggressive), stage, and the patients first response to treatment.

Is he is remission or still in treatment for the cancer? Was the cancer metastatic. More and more oncologists are seeking out a medication to control the cancer rather than 'cure' it for patients with metastatic disease.

He may want to join a few support groups for more information about the disease:

Online Liposarcoma Support Group
http://listserv.acor.org/archives/l-sarcoma.html

Sarcoma Alliance
http://www.sarcomaalliance.org/Main.html  (+ info)

What does this mean? Extensor mechanism: Insertional myxoid?

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degenerative signal involving the teno-osseous...?
junctions of the quadriceps & patellar tendons with the superior and inferior poles of the patella, respectively. Prepatellar inflammation extends inferiorly along the infrapatellar superficial subcutis space with accompanying the patellar tendinopathy & peritendinous inflammation, not extending into the deep infrapatellar Hoffa fat space? Thanks
Medical speak for 'You banged your knee and it's swollen'.  (+ info)

Will I ever play soccer again? Knee Injury: "Myxoid degeneration in lateral meniscus"?

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The MRI's summary states that my left knee has "Myxoid degeneration in the anterior horn of lateral meniscus with joint effusion". I hurt it in a soccer game 6 months ago, it doesn't hurt now but I haven't put the knee to the test. I'm 25yrs old and quite fit. The doctor painted a grim picture, does anyone have any experience of this? Will I be able to play soccer again?
See a physical therapist - a good one will get you right as rain  (+ info)

Has anyone been diagnosed with Liposarcoma cancer?

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Liposarcoma is a rare cancer. You can find others with the disease at the Sarcoma Alliance, many post there on the bulletin board:

http://www.sarcomaalliance.com/Main.html

You can also visit the ACOR email list:
The Liposarcoma (cancer) Online Support Group
http://listserv.acor.org/archives/l-sarcoma.html

  (+ info)

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