What is pulmonary alveolar proteinosis and lymphangioleiomyomatosis?

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Pulmonary alveolar proteinosis is a rare condition and patients with this disease usually present with insidious dyspnoea that has progressed over months, sometimes with mild systemic symptoms such as low grade fever and weight loss.Usually, it has a benign course with eventual resolution. Rarely, rapid progression to respiratory failure is seen.
Death occurs due to progressive filling of alveoli or superimposed infection.
http://www.histopathology-india.net/PrAlPr.htm
In the rare condition of lymphangioleiomyomatosis (LAM) a bizarre proliferation of smooth muscle cells (LAM cells) in the lung involves the smooth muscle of lymphatics, arteries, veins, bronchioles, and alveolar walls.
Dyspnea is the usual presenting symptom.The condition is characterized clinically by slowly progressive breathlessness and basal shadowing, and three distinctive complications: multiple pneumothoraces, haemoptyses and chylous effusions.Oophorectomy has produced good results. Treatment is by oestrogen antagonists or progestogens but the response is unpredictable and does not always correlate with the presence of oestrogen receptors.
http://www.histopathology-india.net/lymphangioleiomyomatosis.htm  (+ info)

Is Lymphangioleiomyomatosis a genetic disease?

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I'm doing a project on geneticc diseases in science class. We have to choose a genetic disease and I would like to choose Lymphangioleiomyomatosis, which has affected my family so horribly. Help?
"While the exact cause of this disorder is not known, the fact that it occurs only in women leads researchers to believe that it may be transmitted as a sex-linked trait or genetic disposition (a person may carry a gene for a disease but it may not be expressed unless something in the environment triggers the disease). Hormone therapy given to women to combat other medical problem(s) has also been implicated as another possible cause. "  (+ info)

My butt itches - Should I scratch it? Will I get lymphangioleiomyomatosis?

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Concerned
scratch away - just don't get caught!  (+ info)

Help, I cant Breath Just quit smoking.... 25 days and counting now this!?

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I was a smoker for 12 years (started at age 16); I have been smoke free for 25 days now. The fist 10-15 days no problems felt like I was floating, now I feel like crap. I have this feeling in my chest like I want to cough-up a hair ball, I have dry cough, at times I do cough-up some mucus (clear), tightness/tingling in my chest, and I cant get a deep enough breath, post-nasal drip, my chest is sore, it hurts when I breath-in deep, it is to say the least unbearable. I did have asthma when I was a child; it went dormant now it’s back again. I went to the ER today; they did an x-ray, blood work, EKG the works! Thank God nothing wrong (no tumor, no emphysema, no fluid in the lungs, no blood cloth, no heart attack, etc). So with all that eliminated what do I have? Is this a cleansing phase, or is it; Lymphangioleiomyomatosis, Chylous effusions, Dyspnea, Hemoptysis, COPD (chronic obstructive pulmonary disease), chronic bronchitis??? The inhaler only works for 30 MINS. HELP!
There are some nicotine withdrawal symptoms couples with acute bronchitis on me now after 3 weeks of smoking quit, I have/had tightness of chest, shortness of breath, chest wheezing, sore/burning chest, breathlessness and phlegm in the throat but i rarely have nagging cough though. Of course I'm recovering now gradually, the symptoms can be with you or me for weeks. There are folks who had suffered the most during the first month of smoking cessation. Glad you have fine EKG, X-ray and blood test which will rule out many diseases from you!

You can put "nicotine withdrawal symptoms" on "search on questions" just above. You will find many folks had very surprised withdrawal symptoms. Keep it up, don't puff again.  (+ info)

Can heart problems develop from abusing amphetamines?

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and anti depressants? I asked before but got no answers

To put it shortly, I used to abuse pills frequently along with drinking and smoking, all between 15 and 16. (Don't comment on my age I don't care what you think about that) But basically met a girl (around September-October of 2009) she got me clean and ever since then I'll have very brief periods that last from a few seconds to a couple minutes where it feels like my heart is either being pulled backwards or needles are poking it.

Sometimes it doesn't hurt and sometimes it does pretty badly. It usually happens just when I sit or lay down and it only occurs a couple times every 2 weeks.

I also recently discovered one month ago that the only person I love has LAM (lymphangioleiomyomatosis) so that has also put some stress on me since she could die at any moment.


Oh yeah, back when I was 13 around that age before I did any drugs I had problems with acid reflux and vocal nodules but that went away. So is it possible for me to be developing any form of heart disease already at the age of almost 17?

I'll post more details if needed but for now I'm concerned about my own life.

But I actually did get the heart problems while still on my previous life-style of doing drugs. So does that mean I developed one during my abuse phase?
yes and see http://www.sciencedaily.com/releases/2008/06/080604091829.htm  (+ info)

Can heart problems derive from abusing pills earlier in life?

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To put it shortly, I used to abuse pills frequently along with drinking and smoking, all between 15 and 16. (Don't comment on my age I don't care what you think about that) But basically met a girl (around September-October of 2009) she got me clean and ever since then I'll have very brief periods that last from a few seconds to a couple minutes where it feels like my heart is either being pulled backwards or needles are poking it.

Sometimes it doesn't hurt and sometimes it does pretty badly. It usually happens just when I sit or lay down and it only occurs a couple times every 2 weeks.

I also recently discovered one month ago that the only person I love has LAM (lymphangioleiomyomatosis) so that has also put some stress on me since she could die at any moment.


Oh yeah, back when I was 13 around that age before I did any drugs I had problems with acid reflux and vocal nodules but that went away. So is it possible for me to be developing any form of heart disease already at the age of almost 17?

I'll post more details if needed but for now I'm concerned about my own life.
as long u stay clean u should be okay, later u should get a physical examination.  (+ info)

Is Lymphangioleiomyomatosis a genetic disease?

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I'm doing a project on geneticc diseases in science class. We have to choose a genetic disease and I would like to choose Lymphangioleiomyomatosis, which has affected my family so horribly. Help?
Lymphangioleiomyomatosis, commonly known as LAM, is a rare disorder of unknown etiology, characterized by an unusual type of muscle cell that invades the tissues of the lungs, including the airways and blood and lymph vessels. Over time, these muscle cells obstruct the flow of air, preventing the lungs from providing oxygen to the rest of the body. LAM may be associated with a genetic disorder known as Tuberous Sclerosis (TS).

Since the etiology of the disease is unknown and referred to many times as "idiopathic" there is no proof that it is genetic. While I admire your motivation, it will be difficult to find research that can definitively state the genetic nature of LAM. However, that doesn't mean you can't rule it out.

I would suggest that you search the Internet for any research devoted to LAM. You could start with the LAM Foundation web site at:

www.thelamfoundation.org

It is people like you who have a passion for finding a cause (and hopefully a cure) for diseases like LAM that make life better. Good luck to you and I hope your project is the best in your science class. Who knows, you may be the one to finally figure out LAM and find a cure to help your loved ones.  (+ info)

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