FAQ - motor neuron disease
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Does anybody have information on any new treatments or drugs to help people with Motor Neuron Disease?


My Uncle has recently been diagnosed with Motor Neuron Disease.He is willing to travel overseas if there is any possibility of new treatments or trials which may be beneficial to him. You could not meet a more decent man and so want to help him by finding out anything at all which may help control this horrible disease. Thanks
Can anyone tell me where or how we go to get this stem cell research ie the names of hospitals/clinics/universities where it is carried out and you can go for treatment. Not available in our country this is why if we knew who to get in contact with it would be a major help. Any information is welcome. Thanks again.
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there's a diet supplement for this however, i believe it was tried to children i don't know about adults  (+ info)

What distinguishes Multiple Sclerosis (especially secondary progressive) from Motor Neuron Disease?


Multiple sclerosis is diagnosed by the lesions on the spinal cord. Motor neuron is characterised by degeneration of the spinal cord  (+ info)

is either parkinsons diease or motor neuron disease genetic ?


Hi Rainiee Jayy, Before I answer your question I need to make one very important clarification---you asked if motor neuron disease is genetic. Here's the clarification: motor neuron disease is NOT a single disease, it is a group of diseases (each having its own name)...motor neuron diseases are often separated into groups, for instance, upper motor neuron diseases and lower motor neuron diseases, and there are also some that involve both the upper and lower motor neurons! So the only accurate way to answer your question is to say: SOME motor neuron diseases DO have a genetic component and others DO NOT have a genetic component, it all depends on which specific motor neuron disease you are talking about.
Parkinson's Disease, of which there are two main types: primary and secondary, was for a very long, long time thought to have no genetic component----but that thinking changed as scientists/researchers have learned through the human genome project that in some cases there is a decided genetic component to Parkinson's Disease. Most commonly however, persons who develop Parkinson's Disease do so because of damage to a portion of the brain (basal ganglia) that is responsible for motor coordination; other patients develop it because of environmental factors, still others due to the toxic effects of certain drugs that reduce the amount of dopamine (a neurotransmitter) present in the brain.
So while the answer to your question cannot be answered with a strict yes or no, as regards to Parkinson's---the only accurate answer is most often Parkinson's Disease is not genetic BUT there are reported cases where a genetic component most definitely and clearly exists.

If you ask about a specific motor neuron disease, I'll be happy to tell you if it has a genetic component or not.
I hope this helps without confusing you.  (+ info)

anyone know any motor neuron disease that are caused by trauma???


I broke my back a month ago since then i'v been experiencing wierd symptoms not common with a broken back at T7 such as: Dizziness, nausea and lost of feeling in left leg for a few seconds. I have had blood and urine test also a CT and MRI which have all been clean. My Doc and Neurologist think it is something to do with epilepsy or motor neuron disease. However the symptoms have only been comming up since after the crash.

Anyone have any ideas??? all theories welcome I really need help!
I am a 17 year old male. Symptoms: Pain in back, Dizziness, Nausea, Heavy Pressure in chest, head ache and cunfusion. Nothing in any test has come up to give the doctors anything to work with. There is no family history of anything of this nature.
I have had Full Body CT, MRI and X-Rays
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Male or female? What is your age? Other symptoms? Family history of upper/lower motor neuron disease? Anything at all show up on MRI, CT, or x-ray etc.
I would suspect that since symptoms only started after your accident, then it is accident related. T7 is too high to cause numbness in legs, unless you have a lumbar problem too, but don't know it, because the brain is focusing on most symptomatic area, T7. Did they perform low back MRI or just Thoracics?
Also, from a healing perspective.....depending on your whole body injury, you body is producing inflammation, which can produce pain or may increase pressure on nerve roots. Second, you body is starting to heal soft-tissue with fibrous tissue(scar tissue). If scars are forming around the nerves, then there is your nerve lesion.  (+ info)

difference between upper&Lower motor neuron disease.?


difference between upper&Lower motor neuron disease.
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The main differences bet. Upper and Lower Motor Neuron Diseases are:
In Upper MND: contralateral hemiparesis, postural flexion of arm & extension of leg, muscles are hypertonic, tendon reflexes are hyperreactive, muscle atrophy not prominent, no muscle fasciculations, and pathologic reflexes are present.
In Lower MND: paresis limited to specific muscle groups, gait depends on muscles affected, muscles flaccid, tendon reflexes are absent or hypoacitve, muscle atrophy is prominent, muscle fascicualtions present, pathologic reflexes are usually absent.  (+ info)

can teenagers get motor neuron disease?


my pop had it, and died from it.

i was just wondering if teenagers can get it.
or if its just in mature people?
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I'm terrible at reading charts, and this is data from 1993, but the Center for Disease Control releases statistics on causes of death by age group. Apparently that year's stats for MND were:

_____________ All = Men + Women
_ under 1 Year: __1 = __1 + ___
01 to 04 Years: __1 = __1 + ___
05 to 09 Years: ___ = ___ + ___
10 to 14 Years: __1 = __1 + ___
15 to 19 Years: ___ = ___ + ___
20 to 24 Years: __5 = __3 + __2
25 to 29 Years: _10 = __8 + __2
30 to 34 Years: _14 = _13 + __1
35 to 39 Years: _59 = _42 + _17
40 to 44 Years: _91 = _58 + _33
45 to 49 Years: 156 = _87 + _69
50 to 54 Years: 202 = 112 + _90
55 to 59 Years: 301 = 158 + 143
60 to 64 Years: 419 = 219 + 200
65 to 69 Years: 656 = 354 + 302
70 to 74 Years: 697 = 331 + 366
75 to 79 Years: 551 = 282 + 269
80 to 84 Years: 342 = 160 + 182
85 to 89 Years: 138 = _61 + _77
90 to 94 Years: _32 = _16 + _16
95 to 99 Years: __9 = __4 + __5

Sorry if that chart didn't come out right, but its rows broken down by age at time of death, in three columns; total, men, and women. As you can see, there were two deaths under age five, and a single teenage death, so yes; a teenager could get MND, though it is very very very rare. I hope that's helpful. Sorry for your loss.

Linked is the PDF I tried to work from.  (+ info)

Is anybody out here aware of the MOTOR NEURON DISEASE?


the same one that Stephen Hawkings suffers from?

I lost my mother to this disease.

I am trying to find people whose loved ones have suffered from this deadly disease.
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well ive never hear about that disease but im sorry about your mom.  (+ info)

Is there any reliable treatment for Motor Neuron disease?


I have an aunt who is suffering from Motor Neuron disease. I have done a lot of searching on the Web and I find that it is a rare condition, and there is no known cure for it.

My aunt is a very sweet person. She has been suffering from this condition for the past three years. They have been trying different kinds of medication, but have not been able to even stop the degeneration, let alone make it better.

We hail from India and my aunt lives in Chennai, India. If there is any treatment to at least stop it from become worse from now, they will be happy to do that.

My question is, is there any treatment centre for Motor Neuron disease or a doctor who has experience with it anywhere in India?

Any information on this topic would be helpful.
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There is no cure or standard treatment for the MNDs. Symptomatic and supportive treatment can help patients be more comfortable while maintaining their quality of life. The drug riluzole (RilutekĀ®), which as of this date is the only drug approved by the U.S. Food and Drug Administration to treat ALS, prolongs life by 2-3 months but does not relieve symptoms. Other medicines that may help reduce symptoms include muscle relaxants such as baclofen, tizanidine, and the benzodiazepines for spasticity; glycopyrrolate and atropine to reduce the flow of saliva; quinine or phenytoin for cramps; anticonvulsants and nonsteroidal anti-inflammatory drugs to relieve pain; tranquilizers to help with sleeping problems; antidepressants; and botulinum toxin, amitriptyline, and other anticholinergic drugs to control drooling. Some patients may require stronger medicines such as morphine to cope with musculoskeletal abnormalities or pain in later stages of the disorders, and opiates are used to provide comfort care in terminal stages of the disease.  (+ info)

what is Indian varient of Motor Neuron Disease or Restricted anterior horn cell disorder??


recently i am suffering from muscle weekness in my right hand. i did many tests to know the reason and visited many neurophysisians. they dignosed it as indian varient of motor neuron disease or restricted anterior horn cell disease. this type affects some perticular region and not the whole body. but i didn't find any reference of it on the net. want to know wheather there exists any such indian subtype.
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Kunal what do you want to know - your diagnosis - or how it will effect you
You can find good medicines in homoeopathy by which u can prevent further progress  (+ info)

My mother has been diagnosed with motor neuron dysfunction what are its causes?


Does it means that she has the Motor neuron Disease she has just been investigated with an EMG, is there any other test to confirm that this is the only disease she might have? she has weakness in speech and swallowing but no sing of weakness in arms or leg is there any other cause of Motor neuron dysfunction other then MND
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here's help from Web MD dot-com

Motor neuron disease comprises a group of severe disorders of the nervous system characterized by progressive degeneration of motor neurons (neurons are the basic nerve cells that combine to form nerves). Motor neurons control the behavior of muscles. Motor neuron diseases may affect the upper motor neurons, nerves that lead from the brain to the medulla (a part of the brain stem) or to the spinal cord, or the lower motor neurons, nerves that lead from the spinal cord to the muscles of the body, or both. Spasms and exaggerated reflexes indicate damage to the upper motor neurons. A progressive wasting (atrophy) and weakness of muscles that have lost their nerve supply indicate damage to the lower motor neurons.

Resources
Amyotrophic Lateral Sclerosis Association
27001 Agoura Road
Suite 150
Calabasas Hills, CA 91301-5104
USA
Tel: 8188809007
Fax: 8188809006
Tel: 8007824747
TDD: 8185933540
Email: [email protected]
Internet: http://www.alsa.org

Families of Spinal Muscular Atrophy
P.O. Box 196
Libertyville, IL 60048
Tel: (847)367-7620
Fax: (847)367-7623
Tel: (800)886-1762
Email: [email protected]
Internet: http://www.curesma.com

Motor Neurone Disease Association
P.O. Box 246
Northampton, Intl NN1 2PR
United Kingdom
Tel: 44 1604 250505
Fax: 44 1604 624726
Email: [email protected]
Internet: http://www.mndassociation.org

Muscular Dystrophy Association
3300 E. Sunrise Dr
Tucson, AZ 85718
USA
Tel: 5205292000
Fax: 5205295300
Tel: 8003444863
Email: [email protected]
Internet: http://www.mdausa.org

National Institute of Neurological Disorders and Stroke (NINDS)
31 Center Drive
8A07
Bethesda, MD 20892-2540
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
Email: [email protected]
Internet: http://www.ninds.nih.gov/

International Alliance of ALS/MND Associations
P.O. Box 246
Northampton, NN1 2PR
United Kingdom
Email: [email protected]
Internet: http://www.alsmndalliance.org/  (+ info)

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