Has anyone had Lebers Hereditary optic Neuropathy in one eye and not have it move to the other eye?

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Lebers hereditary Optic Neuropathy is a genetic disease affecting the optic nerve. It is a bilateral illness .
Leber's Hereditary Optic Neuropathy is a rare condition which can cause loss of central vision. It usually affects men, most commonly in the late twenties or early thirties, but the symptoms can happen at any age, to men or women. Leber's Hereditary Optic Neuropathy was first described by Theodore Leber in the 19th century, but they only really started to understand the inheritance and cause of Leber's in the late 1980's. Usually Leber's affects one eye FIRST, so central vision is lost in that eye over a period of a few weeks. One or two months later, the second eye is affected in the same way. The time when someone is losing their eyesight is often called the 'acute' period. After a few more weeks, the eyesight stops getting worse. Although that describes the most common pattern for Leber's, it can also affect someone very suddenly, or can affect them more gradually over a period of years. Leber's is a genetic condition, that is, it is passed down through the family. Not everyone in a family affected by Leber's will lose their eyesight, and it is not yet known how to tell who will get symptoms. The present knowledge is that Leber's is inherited through a gene which is only passed on through the egg cell from the mother. Men cannot pass on Leber's Hereditary Optic Neuropathy to their children. Leber's Hereditary Optic Neuropathy is linked to a number of genes, all in the DNA of structures called Mitochondria. These provide energy to the cells of the body. It is thought that the particular gene changes linked to Leber's Hereditary Optic Neuropathy lower the amount of energy available to the cells of the optic nerve and retina. These cells are damaged and can even die because of this lack of energy. The damage to the optic nerve and retina is what causes the symptoms of Leber's.
There is no record of only one eye being affected only, without the second eye being affected at a later date.
Hope this helps
Matador 89  (+ info)

Any experts out there on Optic Neuropathy/Neurology?

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I have someone I care about who needs answers. She has gone to MANY specialists, had Radial Keropathy (RK) procedure done before laser procedures were ever utilized. She suffers with EXTREME pain on a daily basis. Anybody out there that suffers with this? Please help!! Thank you!
you can research some eye diseases and disorders at this site.

http://www.mic.ki.se/diseases/c11.html...

Why  (+ info)

anyone ever used risperdal for treatment of visual disturbances for recent blindness due to optic neuropathy?

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recent optic neuritiis has left her (50yo F), dx MS, basically blind (light perception) only, she is also unsteady and objects appear and disappear (bathrooms in hallways......) Thanks
yes i have once***  (+ info)

What does it mean to have optical neuropathy?

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I was recently tested for MS and anurism due to my left eye being diagnosed as being optic neuropathy - what causes this and could I go blind from it?
optic neuropathy literally means a disease of the optical nerve, the one that goes from your eye to the brain.

only your doctor can give you a prognosis because he knows more about you than you are telling us.  (+ info)

Does any one know any treatment for " ion squemic optic neuropathy"?

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i think it's spelled Ischemic Optic Neuropathy (ION)
here is a link for a website devoted to it:
http://www.ifond.org/ischemic.php3
good luck  (+ info)

Traumatic optic neuropathy Question...?

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If a child 6-7 years was in a car accident, where there is a scar above his left eyebrow, can he have sign of the above when he is 17 years old.
I am asking because the other possibility is glaucoma, but his IOP (intraoccular pressure is normal) and having non tension glaucoma at his age is just crazy. At first the eye physician said that this is very unlikely at his age, but then when he took a closer look, said that he is not so sure.
He started wearing glasses about 3 years ago, but at the time they said it is normal.
His vision wearing glasses is ok and he does not complain of any pains, headaches, vomiting etc...
thank you
Definitely. traumatic optic neuropathy is an irreversible problem. If he has a pupillary defect and normal pressure, this is a likely cause - especially if he noticed a decline after the accident. The force for these injuries is usually a severe blow to the brow.  (+ info)

After an ischemic stroke, how long does it usually take for the brain swelling to peak & subside?

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I am asking this question for the case of a large ischemic stroke in which around 2/3 of the left side of the brain has been impaired. Presumably it takes longer for the brain swelling to subside for a large stroke than a minor stroke.

A follow-up question is, what is the mechanism by which the brain swelling subsides? Does the swelling subside only due to the death of brain cells?
Hi.

After an ischemic stroke, there are actually two types of brain swelling(aka cerebral edema) that occur.

1. First, there is intracellular edema, which is also called cytotoxic edema. When a brain cell's oxygen supply is interrupted, the cell is no longer able to regulate the concentration of its own electrolytes. As a result, while the cell is dying, water rushes into the cell from extracellular compartments. This event occurs within a few hours (2-3 hrs) after the stroke happens.

2. The second type of edema is called vasogenic edema (aka interstitial edema) and occurs later than cytotoxic edema. In this case, after an ischemic stroke, the blood vessels downstream break down and begin to leak water and proteins into the area of dead brain. These events occur with 6-12 hours and progresses for about 3 days.

When someone has a large stroke, it is the rapid progression of interstitial edema that is potentially lethal. The estimated peak of interstitial edema is about 3 days, but more realistically it is about 3-5 days.

Eventually as the neurons and its supporting cells die off and are replaced with scar tissue, the cytotoxic edema subsides. Also, as the blood vessels repair themselves or either die off, the leakiness of the blood vessels subside as well. Thus, to answer your question, the resolution of swelling is not directly due to the death of neurons, but it is due rather to the decrease of inflammation and the gradual repair of the blood vessels.

Hope I was able to answer your question!  (+ info)

What is the root cause of itchy sensation due to neuropathy?

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I have tingling, electric-like needle pin puncture and itchy sensations in my body. I thought this was an allergy but I doubt that it is related to neuropathy. Please help me to recognized the difference between allergy and neuropathy. I have history of allergy and also neuropathy. I am confused.
Can a neuropahtic pain have mild symptoms of itchy sensation similar to allergy?
neuropathy will usually have a more pain-like tingling sensation, allergy is more itchy, no pain involved since there is no nerve involvement with an allergy.  (+ info)

What is the best treatment for the pain of Neuropathy?

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I have had neuropathy for at least 8 years and the pain appears to be getting more difficult to control. The pain is primarily in my feet and lower legs. I take Lyrica twice a day but have all of the side effects associated with this product. I need help desperately but don't know where to find it. My neurologist has ordered a neuropathy profile on me and has tried several different kinds of medicines, all of which have been totally innefective. Any ideas?
Meditation, self-hypnosis (mind control). This sounds wierd, but it works. It is an arduous process, but you can learn.

If you can find a quiet place to lay and close your eyes, do so. Clear your mind of all thoughts, and try to "see" in your minds eye the affected area. Think to yourself "there is no pain". Do this as often as necessary. It does work. It is much better than medicationg. Narcotic pain relievers are just too addictive. I am now trying to get off of them after a number of years of prescribed use. It is more painful to stop taking the pills than the original pain was. Now I am in misery if I do not take Suboxone - a medication used to assist in Opioid Addiction Therapy. It stops the withdrawl. But that has nothing to do with you, except to say PLEASE be careful if you are taking narcotic pain relievers.  (+ info)

What remedies are there to relieve foot neuropathy caused by diabetes?

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My mom has Type II diabetes and is suffering from neuropathy in her feet. I have read on websites that there is treatment but was curious if any of you out there who have this have any remedies for relief...like home remedies or know of any kind of over the counter cream that helps? She also has the burning and tingling sensation at times that keep her up at night. Diabetic community....PLEASE HELP!!! Any suggestions?
I found this article that I think will answer your question.  (+ info)

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