FAQ - psittacosis
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Is Psittacosis chronic or acute?


In humans, after incubation period of 5-14 days, the symptoms of the disease range from inapparent illness to systemic illness with severe pneumonia. It presents chiefly as an atypical pneumonia. In the first week of psittacosis the symptoms mimic typhoid fever: prostrating high fevers, arthralgias, diarrhoea, conjunctivitis, epistaxis and leukopenia. Rose spots can appear and these are called Horder's spots. Splenomegaly is frequent toward the end of first week. Diagnosis can be suspected in case of respiratory infection associated with splenomegaly and/or epistaxis. Headache can be so severe that suggests meningitis and some nuchal rigidity is not unusual. Towards the end of first week stupor or even coma can result in severe cases.

The second week is more akin of acute bacteraemic pneumococcal pneumonia with continuous high fevers, cough and dyspnea. X rays show patchy infiltrates or a diffuse whiteout of lung fields. Bloodwork shows leukopenia, thrombocytopenia and moderately elevated liver enzymes. Differential diagnosis must be made with typhus, typhoid and atypical pneumonia by Mycoplasma, Legionella or Q fever. Exposure history is paramount to diagnosis.

Complications in the form of endocarditis, hepatitis, myocarditis, arthritis, keratoconjunctivitis, and neurologic complications (encephalitis) may occasionally occur. Severe pneumonia requiring intensive-care support may also occur. Fatal cases have been reported (less than 1% of cases).

The infection is treated with antibiotics. Tetracyclines and chloramphenicol are the drugs of choice for treating patients with psittacosis. Most persons respond to oral therapy. For initial treatment of severely ill patients, doxycycline hyclate may be administered intravenously. In past years, tetracycline hydrochloride has been administered to patients intravenously. Remission of symptoms usually is evident within 48-72 hours. However, relapse can occur, and treatment must continue for at least 10-14 days after fever abates. Erythromycin probably is the best alternative agent for persons for whom tetracycline is contraindicated .

So, to answer your question, it's acute and easily curable. God bless!  (+ info)

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