A member of the annexin family that is a substrate for a tyrosine kinase, ONCOGENE PROTEIN PP60(V-SRC). annexin a2 occurs as a 36-KDa monomer and in a 90-KDa complex containing two subunits of annexin a2 and two subunits of S100 family PROTEIN P11. The monomeric form of annexin a2 was formerly referred to as calpactin I heavy chain.