An abnormal congenital condition, associated with defects in the lamin type a gene, which is characterized by premature aging in children, where all the changes of cell senescence occur. It is manifested by premature greying; hair loss; hearing loss (deafness); cataracts (cataract); arthritis; osteoporosis; diabetes mellitus; atrophy of subcutaneous fat; skeletal hypoplasia; elevated urinary hyaluronic acid; and accelerated atherosclerosis. Many affected individuals develop malignant tumors, especially sarcoma.


Leave a message about 'Progeria'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.