A 90-amino acid peptide derived from post-translational processing of pro-opiomelanocortin (POMC) in the pituitary gland and the hypothalamus. It is the C-terminal fragment of POMC with lipid-mobilizing activities, such as lipolysis and steroidogenesis. Depending on the species and the tissue sites, beta-LPH may be further processed to yield active peptides including gamma-lipotropin; beta-msh; and endorphins.