Hyperalgesia; Hyperalgesia, Tactile; Hyperalgesia, Thermal

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Symptoms:

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	Active principles	Rating	Bibliogr.
1	Carrageenan	100	+
2	Capsaicin	80	+
3	Freund's Adjuvant	71	+
4	TRPV Cation Channels	43	+
5	Receptors, N-Methyl-D-Aspartate	41	+
6	Formaldehyde	41	+
7	Morphine	39	+
8	Receptors, Prostaglandin E	36	+
9	Receptor, Bradykinin B1	33	+
10	Dinoprostone	32	+
11	Receptors, Bradykinin	32	+
12	Amines	31	+
13	Receptors, Purinergic P2X3	30	+
14	Protein Kinase C-epsilon	30	+
15	Cyclohexanecarboxylic Acids	29	+
16	Dizocilpine Maleate	29	+
17	gamma-Aminobutyric Acid	29	+
18	Receptor, Cannabinoid, CB2	28	+
19	Receptors, Purinergic P2X2	27	+
20	Acids	26	+
21	Nitroparaffins	26	+
22	Receptors, Opioid	25	+
23	Nerve Growth Factor	25	+
24	Ankyrins	25	+
25	Receptors, Opioid, mu	25	+
26	Kallidin	24	+
27	Substance P	24	+
28	NAV1.8 Voltage-Gated Sodium Channel	24	+
29	Bee Venoms	23	+
30	Ketamine	23	+
31	Naloxone	23	+
32	Calcium Channels, R-Type	22	+
33	Cyclooxygenase 2	21	+
34	Bradykinin	21	+
35	Piperidines	21	+
36	Pyrazoles	21	+
37	Sodium Channels	20	+
38	Proto-Oncogene Proteins c-fos	20	+
39	Kaolin	20	+
40	Opioid Peptides	20	+
41	Protein Kinase C	20	+
42	Oligodeoxyribonucleotides, Antisense	20	+
43	Acid Sensing Ion Channels	19	+
44	Dithionitrobenzoic Acid	19	+
45	Physalaemin	19	+
46	Interleukin-1beta	19	+
47	Cannabinoids	18	+
48	Cyclooxygenase 1	18	+
49	Cinnamates	18	+
50	Receptors, Neurokinin-1	17	+
51	omega-Conotoxins	17	+
52	Vesicle-Associated Membrane Protein 2	17	+
53	6-Cyano-7-nitroquinoxaline-2,3-dione	17	+
54	p38 Mitogen-Activated Protein Kinases	17	+
55	Prostaglandin-Endoperoxide Synthases	17	+
56	Receptors, Prostaglandin E, EP2 Subtype	16	+
57	Excitatory Amino Acids	16	+
58	Quinuclidines	16	+
59	TRPC Cation Channels	16	+
60	Bornanes	16	+
61	Benzophenanthridines	16	+
62	2-Amino-5-phosphonovalerate	16	+
63	Receptors, Adrenergic, alpha-2	16	+
64	Palmitic Acids	16	+
65	Endocannabinoids	16	+
66	Receptors, Purinergic P2	15	+
67	Calcitonin Gene-Related Peptide	15	+
68	Thymic Factor, Circulating	15	+
69	Indomethacin	15	+
70	Receptor, PAR-2	15	+
71	Dynorphins	15	+
72	Morphine Derivatives	15	+
73	NG-Nitroarginine Methyl Ester	15	+
74	Polyunsaturated Alkamides	15	+
75	Methysergide	14	+
76	Meclizine	14	+
77	Receptors, Opioid, kappa	14	+
78	Ribosome Inactivating Proteins, Type 1	14	+
79	Polycyclic Compounds	14	+
80	Receptors, Cannabinoid	14	+
81	Receptors, Drug	14	+
82	Hydroxylamine	14	+
83	Minocycline	14	+
84	Neurotrophin 3	14	+
85	Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide	14	+
86	Nitric Oxide Synthase Type I	14	+
87	Lidocaine	14	+
88	G-Protein-Coupled Receptor Kinase 2	14	+
89	Streptozocin	13	+
90	Calcium Channels, T-Type	13	+
91	Nefopam	13	+
92	Crotalid Venoms	13	+
93	Glial Fibrillary Acidic Protein	13	+
94	Glycine	13	+
95	N-Methylaspartate	13	+
96	Arachidonic Acids	13	+
97	Dextrorphan	13	+
98	Spider Venoms	13	+
99	Indoles	13	+
100	Receptors, Opioid, delta	13	+
101	Amidohydrolases	12	+
102	Cyclic AMP-Dependent Protein Kinases	12	+
103	Naphthalenes	12	+
104	TNF Receptor-Associated Factor 1	12	+
105	Alkaloids	12	+
106	Dipyrone	12	+
107	Naltrexone	12	+
108	Cystinyl Aminopeptidase	12	+
109	Calcium Channels, N-Type	12	+
110	NADPH Dehydrogenase	12	+
111	Nitric Oxide	12	+
112	Diterpenes	12	+
113	Isoenzymes	12	+
114	Butadienes	12	+
115	Acetates	12	+
116	Interleukin-1	12	+
117	Receptor, trkA	12	+
118	Receptors, Interleukin-1 Type I	12	+
119	Strychnine	12	+
120	Isoindoles	12	+
121	Receptors, Kainic Acid	12	+
122	Nitroso Compounds	12	+
123	Versicans	12	+
124	Receptors, Prostaglandin E, EP1 Subtype	11	+
125	omega-Agatoxin IVA	11	+
126	Ruthenium Red	11	+
127	Quinoxalines	11	+
128	Serotonin	11	+
129	Receptors, Metabotropic Glutamate	11	+
130	Mollusk Venoms	11	+
131	Nerve Growth Factors	11	+
132	Hydroxylamines	11	+
133	Sodium Salicylate	11	+
134	Guanylate Kinase	11	+
135	Receptors, Amino Acid	11	+
136	Receptor, Cholecystokinin B	11	+
137	Plant Extracts	11	+
138	Amino Acids, Dicarboxylic	11	+
139	Chemokine CX3CL1	11	+
140	Tumor Necrosis Factor-alpha	11	+
141	Prochlorperazine	11	+
142	Evans Blue	11	+
143	Loperamide	11	+
144	Morpholines	11	+
145	Ibuprofen	11	+
146	Diclofenac	11	+
147	Cytokines	11	+
148	Membrane Proteins	10	+
149	Glutamic Acid	10	+
150	Pertussis Toxin	10	+
151	Trimebutine	10	+
152	Adenosine	10	+
153	Calgranulin B	10	+
154	omega-Conotoxin GVIA	10	+
155	Benzoxazines	10	+
156	Procollagen N-Endopeptidase	10	+
157	Type C Phospholipases	10	+
158	Nitric Oxide Synthase	10	+
159	Dextromethorphan	10	+
160	Pyrrolidines	10	+
161	Lectins	10	+
162	Cations, Divalent	10	+
163	Receptor, Cannabinoid, CB1	10	+
164	Eugenol	9	+
165	Arginine	9	+
166	GABA Plasma Membrane Transport Proteins	9	+
167	Bicuculline	9	+
168	Chemokines, CX3C	9	+
169	Oxymorphone	9	+
170	Sulfonamides	9	+
171	Triazines	9	+
172	Oligopeptides	9	+
173	Receptors, Purinergic P2Y	9	+
174	Acetic Acid	9	+
175	Maleimides	9	+
176	Pyridines	9	+
177	Adenosine Kinase	9	+
178	Receptor, Adenosine A1	9	+
179	Zymosan	9	+
180	Hydromorphone	9	+
181	Calcium Channels	9	+
182	Peroxynitrous Acid	9	+
183	Xanthines	9	+
184	Tetrodotoxin	8	+
185	Chlorophenols	8	+
186	Enkephalins	8	+
187	alpha-Methyltyrosine	8	+
188	Oligonucleotides, Antisense	8	+
189	Cyclin-Dependent Kinase 5	8	+
190	Estranes	8	+
191	Caproates	8	+
192	Hydrochloric Acid	8	+
193	Receptor, Endothelin B	8	+
194	Receptor, Bradykinin B2	8	+
195	Picrotoxin	8	+
196	Receptors, sigma	8	+
197	Prostaglandin Antagonists	8	+
198	Ketanserin	8	+
199	RNA, Messenger	8	+
200	Antibodies, Blocking	8	+
201	Receptors, Melatonin	8	+
202	Procyclidine	8	+
203	Mitogen-Activated Protein Kinases	8	+
204	Activating Transcription Factor 3	8	+
205	8-Bromo Cyclic Adenosine Monophosphate	8	+
206	Nalorphine	8	+
207	Oligoribonucleotides, Antisense	8	+
208	Nitrogen Oxides	8	+
209	Receptors, Adrenomedullin	8	+
210	Adenylate Cyclase	8	+
211	Ketorolac	8	+
212	Iodoacetic Acid	8	+
213	Kininogens	8	+
214	Receptor, Melanocortin, Type 4	8	+
215	Nitric Oxide Synthase Type II	7	+
216	Isoquinolines	7	+
217	Prostaglandins E, Synthetic	7	+
218	Phosphoserine	7	+
219	FMRFamide	7	+
220	Clonidine	7	+
221	Acetaminophen	7	+
222	Fentanyl	7	+
223	Receptors, Serotonin, 5-HT3	7	+
224	Calcium Channels, L-Type	7	+
225	Protein Precursors	7	+
226	Guanethidine	7	+
227	Amitriptyline	7	+
228	Receptors, Prostaglandin E, EP4 Subtype	7	+
229	Terpenes	7	+
230	Excitatory Amino Acid Transporter 2	7	+
231	Isoxazoles	7	+
232	Neuropeptides	7	+
233	Lysophospholipids	7	+
234	Baclofen	7	+
235	Indazoles	7	+
236	Phenols	7	+
237	Polyisoprenyl Phosphates	7	+
238	Phentolamine	7	+
239	Neurokinin A	7	+
240	Nitrites	7	+
241	Solute Carrier Family 12, Member 2	7	+
242	Dinitrophenols	7	+
243	Tramadol	7	+
244	Amino Acid Transport System X-AG	7	+
245	Cycloleucine	7	+
246	Endorphins	7	+
247	Iodoacetates	7	+
248	Peptide Fragments	7	+
249	Cyclic AMP Response Element-Binding Protein	6	+
250	Oncogene Proteins v-fos	6	+
251	Diphenhydramine	6	+
252	Trinitrobenzenesulfonic Acid	6	+
253	Aminopyrine	6	+
254	Receptors, Cytokine	6	+
255	Enkephalin, Methionine	6	+
256	Ketoprofen	6	+
257	Lipopolysaccharides	6	+
258	Receptors, Purinergic P2X	6	+
259	Phospholipase C beta	6	+
260	Kainic Acid	6	+
261	Prostaglandins	6	+
262	Synaptophysin	6	+
263	Oxadiazoles	6	+
264	Peptides	6	+
265	Buprenorphine	6	+
266	alpha-MSH	6	+
267	Cinanserin	6	+
268	Receptor, Adenosine A2A	6	+
269	Imidazoles	6	+
270	Receptors, Neuropeptide Y	6	+
271	Phenethylamines	6	+
272	Dipeptides	6	+
273	Nitrobenzenes	6	+
274	Dexmedetomidine	6	+
275	Carbamates	6	+
276	Prostaglandins E	6	+
277	Polysaccharides	6	+
278	Pyrrolidinones	6	+
279	Disulfides	6	+
280	Mitogen-Activated Protein Kinase Kinases	6	+
281	Receptors, Cholecystokinin	6	+
282	Receptors, GABA-A	5	+
283	Receptors, Glutamate	5	+
284	Agmatine	5	+
285	Mexiletine	5	+
286	Nerve Tissue Proteins	5	+
287	Muscimol	5	+
288	GTP-Binding Proteins	5	+
289	alpha7 Nicotinic Acetylcholine Receptor	5	+
290	Occludin	5	+
291	Dronabinol	5	+
292	Receptors, AMPA	5	+
293	Cyclohexanols	5	+
294	Aminoquinolines	5	+
295	Receptor, Endothelin A	5	+
296	Interleukin-6	5	+
297	Ondansetron	5	+
298	Cation Transport Proteins	5	+
299	Melatonin	5	+
300	Nitriles	5	+
301	Cyclic AMP	5	+
302	Furans	5	+
303	Sulfones	5	+
304	Nipecotic Acids	5	+
305	Adenosine Triphosphate	5	+
306	Sodium Chloride	5	+
307	Idazoxan	5	+
308	Carbazoles	5	+
309	Endothelin-1	5	+
310	Benzofurans	5	+
311	Cyproheptadine	5	+
312	Sumatriptan	5	+
313	Symporters	5	+
314	Oxycodone	5	+
315	Bupivacaine	5	+
316	Reserpine	5	+
317	Anilides	5	+
318	Interleukin 1 Receptor Antagonist Protein	5	+
319	Pentoxifylline	5	+
320	Benzeneacetamides	5	+
321	Receptors, G-Protein-Coupled	4	+
322	Prostaglandin D2	4	+
323	Cyclic GMP	4	+
324	Receptor, Metabotropic Glutamate 5	4	+
325	Stilbenes	4	+
326	Norepinephrine	4	+
327	Oximes	4	+
328	Brain-Derived Neurotrophic Factor	4	+
329	Pyrroles	4	+
330	Receptors, Serotonin	4	+
331	Peroxidase	4	+
332	Cyclic N-Oxides	4	+
333	Immune Sera	4	+
334	Glutamates	4	+
335	Yohimbine	4	+
336	Extracellular Signal-Regulated MAP Kinases	4	+
337	NF-kappa B	4	+
338	Bicyclo Compounds	4	+
339	Indans	4	+
340	Receptor, Serotonin, 5-HT2A	4	+
341	Antibodies	4	+
342	Dexamethasone	4	+
343	Aldehyde Reductase	4	+
344	Glucosides	4	+
345	Lysine	4	+
346	Benzoates	4	+
347	Enkephalin, Ala(2)-MePhe(4)-Gly(5)-	4	+
348	Ethanolamines	4	+
349	Plant Oils	4	+
350	Peptides, Cyclic	4	+
351	Somatostatin	4	+
352	Curcumin	4	+
353	Intracellular Signaling Peptides and Proteins	4	+
354	Cholecystokinin	4	+
355	Carbamazepine	3	+
356	Receptors, Corticotropin-Releasing Hormone	3	+
357	Eicosanoids	3	+
358	Benzamides	3	+
359	Interleukin-13	3	+
360	Metalloendopeptidases	3	+
361	Superoxides	3	+
362	Antivenins	3	+
363	Caffeine	3	+
364	Tyrosine	3	+
365	Ethanol	3	+
366	Interleukin-10	3	+
367	Endothelins	3	+
368	Alprostadil	3	+
369	Aspirin	3	+
370	MicroRNAs	3	+
371	Nitrates	3	+
372	Acetylcholine	3	+
373	Nitroprusside	3	+
374	Drugs, Chinese Herbal	3	+
375	Calcium	2	+
376	Proline	2	+
377	Botulinum Toxins, Type A	2	+
378	Piperazines	2	+
379	Biphenyl Compounds	2	+
380	Blood Glucose	2	+
381	Amiodarone	2	+
382	Octreotide	2	+
383	Superoxide Dismutase	2	+
384	Malondialdehyde	2	+
385	Interleukins	2	+
386	Midazolam	2	+
387	Propranolol	2	+
388	Hemoglobins	2	+
389	Nifedipine	1	+
390	Recombinant Proteins	1	+
391	Glucocorticoids	1	+
392	Estradiol	1	+
393	Insulin	1	+

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