Osteoarthritis, Knee

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knee; osteoarthritis; osteoarthritis, knee

	Active principles	Rating	Bibliogr.
1	Glucosamine	100	+
2	Hyaluronic Acid	88	+
3	Naproxen	70	+
4	Matrix Metalloproteinase 13	68	+
5	Iodoacetates	68	+
6	Piroxicam	56	+
7	Diclofenac	55	+
8	Anthraquinones	55	+
9	Chondroitin Sulfates	54	+
10	Collagenases	54	+
11	Matrix Metalloproteinase 3	51	+
12	Etodolac	50	+
13	Acetaminophen	50	+
14	Aggrecans	45	+
15	Pyrazoles	45	+
16	Proteoglycans	44	+
17	Iodoacetic Acid	43	+
18	Collagen Type II	40	+
19	Glycosaminoglycans	38	+
20	Sulfonamides	38	+
21	Ibuprofen	35	+
22	Sulfones	33	+
23	Lactones	33	+
24	Keratan Sulfate	31	+
25	Chondroitin	30	+
26	Metalloproteins	27	+
27	Metalloproteases	27	+
28	Thiazines	26	+
29	Bromelains	25	+
30	Indoleacetic Acids	25	+
31	Metalloendopeptidases	23	+
32	Uronic Acids	23	+
33	Organic Chemicals	23	+
34	Matrix Metalloproteinases	21	+
35	Matrilin Proteins	21	+
36	Microbial Collagenase	21	+
37	Indoprofen	20	+
38	Plant Extracts	20	+
39	Interleukin-1beta	20	+
40	Extracellular Matrix Proteins	19	+
41	Cyclooxygenase 2	19	+
42	Tramadol	19	+
43	Matrix Metalloproteinase 1	18	+
44	Phenylpropionates	18	+
45	Doxycycline	18	+
46	Procollagen N-Endopeptidase	18	+
47	Polynucleotides	18	+
48	Mineral Waters	17	+
49	Triamcinolone	16	+
50	Ketoprofen	16	+
51	Prostaglandin-Endoperoxide Synthases	16	+
52	Diphenylamine	16	+
53	Tissue Extracts	16	+
54	Propionates	16	+
55	Calcium Pyrophosphate	16	+
56	Oxycodone	15	+
57	Tissue Inhibitor of Metalloproteinases	15	+
58	Endopeptidases	15	+
59	Paraffin	14	+
60	Interleukin-1	14	+
61	Cartilage Oligomeric Matrix Protein	14	+
62	Dinoprostone	14	+
63	Thiophenes	14	+
64	Adrenal Cortex Hormones	14	+
65	Methylprednisolone	14	+
66	Interleukin 1 Receptor Antagonist Protein	14	+
67	Bone Cements	13	+
68	Membrane Proteins	13	+
69	Cathepsins	13	+
70	Bupivacaine	13	+
71	S-Adenosylmethionine	13	+
72	Pentosan Sulfuric Polyester	12	+
73	Plant Preparations	12	+
74	Cyclic Nucleotide Phosphodiesterases, Type 2	12	+
75	Collagen	12	+
76	Glucocorticoids	12	+
77	ADAM Proteins	12	+
78	Glycosides	12	+
79	Fenoprofen	11	+
80	Isoenzymes	11	+
81	Indenes	11	+
82	Carbazoles	11	+
83	Indomethacin	11	+
84	Gold Compounds	11	+
85	Glycoproteins	11	+
86	Cathepsin K	11	+
87	Drugs, Chinese Herbal	11	+
88	Tissue Inhibitor of Metalloproteinase-1	11	+
89	Osmium	10	+
90	Protein Hydrolysates	10	+
91	Rho Guanine Nucleotide Exchange Factors	10	+
92	Dimethyl Sulfoxide	10	+
93	Receptors, Interleukin-1	10	+
94	Pyrans	10	+
95	Flurbiprofen	9	+
96	Sulfur	9	+
97	Sodium Salicylate	9	+
98	Salicylates	9	+
99	HLA-B39 Antigen	9	+
100	Durapatite	9	+
101	Cyclooxygenase 1	9	+
102	Pyridines	9	+
103	Cysteine Proteases	9	+
104	Sialoglycoproteins	8	+
105	Interleukin-1alpha	8	+
106	Receptor, Bradykinin B2	8	+
107	Etidronic Acid	8	+
108	Waxes	8	+
109	Phenylacetates	8	+
110	Thiazoles	8	+
111	Morphine	8	+
112	Calcitonin	8	+
113	Scopoletin	8	+
114	Sodium Radioisotopes	8	+
115	Oxymorphone	8	+
116	Gelatinases	7	+
117	Tumor Necrosis Factor-alpha	7	+
118	Yttrium	7	+
119	Collagen Type I	7	+
120	Phenylbutyrates	7	+
121	Triamcinolone Acetonide	7	+
122	Placental Extracts	7	+
123	RNA, Messenger	7	+
124	Aspartame	7	+
125	Isoxazoles	7	+
126	Azirines	7	+
127	Bone Morphogenetic Protein 7	7	+
128	Folate Receptor 2	7	+
129	Peptide Hydrolases	7	+
130	Intercellular Signaling Peptides and Proteins	7	+
131	Tranexamic Acid	7	+
132	Lidocaine	7	+
133	Aniline Compounds	7	+
134	Alendronate	7	+
135	Steroids	6	+
136	Phenylbutazone	6	+
137	Capsaicin	6	+
138	Tannins	6	+
139	Chemokine CCL20	6	+
140	Diflunisal	6	+
141	Hydroxyproline	6	+
142	Amides	6	+
143	Codeine	6	+
144	Nitric Oxide	6	+
145	NF-kappa B	6	+
146	Organometallic Compounds	6	+
147	Curcumin	6	+
148	Sulindac	6	+
149	Gels	6	+
150	C-Reactive Protein	6	+
151	Acetylglucosamine	6	+
152	Thrombospondin 1	6	+
153	Substance P	6	+
154	Stigmasterol	6	+
155	Matrix Metalloproteinase 2	6	+
156	Dysprosium	6	+
157	Receptors, Urokinase Plasminogen Activator	6	+
158	Matrix Metalloproteinase 9	6	+
159	Fursultiamin	5	+
160	Acetates	5	+
161	Tetracyclines	5	+
162	Sulfates	5	+
163	Ketorolac	5	+
164	Interleukin-8	5	+
165	Phenols	5	+
166	Yttrium Radioisotopes	5	+
167	Matrix Metalloproteinases, Membrane-Associated	5	+
168	Betamethasone	5	+
169	Tissue Inhibitor of Metalloproteinase-3	5	+
170	Diphosphonates	5	+
171	Osmium Tetroxide	5	+
172	Sodium Chloride	5	+
173	Tantalum	5	+
174	Transforming Growth Factor beta	5	+
175	Nitric Oxide Synthase Type II	5	+
176	Cytokines	5	+
177	SOX9 Transcription Factor	5	+
178	Interleukin-6	5	+
179	Polyethylene	5	+
180	Hydroxychloroquine	5	+
181	Peptide Fragments	4	+
182	Kaolin	4	+
183	Calcium-Binding Proteins	4	+
184	Peptides	4	+
185	Biological Products	4	+
186	Interleukin-17	4	+
187	Tin	4	+
188	Insulin-Like Growth Factor I	4	+
189	Pyrroles	4	+
190	Electron Transport Complex IV	4	+
191	Aspirin	4	+
192	Vitamin E	4	+
193	Prednisolone	3	+
194	Stilbenes	3	+
195	Urokinase-Type Plasminogen Activator	3	+
196	p38 Mitogen-Activated Protein Kinases	3	+
197	Methotrexate	3	+
198	Dehydroepiandrosterone	3	+
199	Plasminogen Activator Inhibitor 1	3	+
200	Galactosides	3	+
201	Mitogen-Activated Protein Kinases	3	+
202	Plant Oils	3	+
203	Antibodies, Monoclonal	3	+
204	Alkaline Phosphatase	3	+
205	Methylmethacrylates	3	+
206	Papain	3	+
207	Samarium	3	+
208	Recombinant Proteins	3	+
209	Vitamin D	3	+
210	Fish Oils	3	+
211	Fibrin Tissue Adhesive	3	+
212	Flavonoids	3	+
213	Cefuroxime	3	+
214	Enoxaparin	2	+
215	DNA	2	+
216	Sodium Pertechnetate Tc 99m	2	+
217	Zirconium	2	+
218	Yttrium Isotopes	2	+
219	Tolmetin	2	+
220	Botulinum Toxins, Type A	2	+
221	Creatine	2	+
222	Calcium	2	+
223	Radioisotopes	2	+
224	Methocarbamol	2	+
225	Niobium	2	+
226	Rhenium	2	+
227	Prilocaine	2	+
228	Fentanyl	2	+
229	Chromium Alloys	2	+
230	Morpholines	2	+
231	Polyethylenes	2	+
232	Excitatory Amino Acids	2	+
233	Carrageenan	2	+
234	Firefly Luciferin	2	+
235	Receptors, Amino Acid	2	+
236	Freund's Adjuvant	2	+
237	Epinephrine	2	+
238	Gadolinium DTPA	2	+
239	Dalteparin	2	+
240	Technetium	2	+
241	Antithrombin Proteins	2	+
242	Clonidine	2	+
243	Menthol	2	+
244	Creatinine	2	+
245	Collagen Type III	2	+
246	Hydroxyapatites	2	+
247	Nacre	1	+
248	Silicates	1	+
249	Pregnenes	1	+
250	Sufentanil	1	+
251	Thrombin	1	+
252	Gadolinium	1	+
253	Factor Xa	1	+
254	Decorin	1	+
255	Colloids	1	+
256	Methylmethacrylate	1	+
257	Polysaccharides	1	+
258	Serum Albumin, Bovine	1	+
259	Hydrocodone	1	+
260	Cefazolin	1	+
261	Iothalamate Meglumine	1	+
262	Neostigmine	1	+
263	Hemoglobins	1	+
264	Butanones	1	+
265	Heparin, Low-Molecular-Weight	1	+
266	Pirinitramide	1	+
267	Mepivacaine	1	+
268	Benzylamines	1	+
269	Manganese Compounds	1	+
270	Alloys	1	+
271	Lectins, C-Type	1	+
272	Colchicine	1	+
273	Bradykinin	1	+
274	Luciferases, Firefly	1	+
275	Fibrin	1	+
276	Zymosan	1	+
277	Factor VIII	1	+
278	Warfarin	1	+
279	Cloxacillin	1	+
280	Polymethyl Methacrylate	1	+
281	6-Cyano-7-nitroquinoxaline-2,3-dione	1	+
282	Ferric Compounds	1	+
283	Glycine	1	+
284	HLA-B51 Antigen	1	+
285	Polytetrafluoroethylene	1	+
286	Hexamethonium Compounds	1	+
287	Tenascin	1	+
288	Platelet-Derived Growth Factor	1	+
289	Cefamandole	1	+
290	Diphosphates	1	+
291	Technetium Tc 99m Exametazime	1	+
292	Calcitonin Gene-Related Peptide	1	+
293	Biglycan	1	+
294	Gold Radioisotopes	1	+
295	Fibrillar Collagens	1	+
296	Meperidine	1	+
297	Chymopapain	1	+
298	Allopurinol	1	+
299	Antithrombin III	1	+
300	Transforming Growth Factor beta1	1	+
301	Ascorbic Acid	1	+
302	Propofol	1	+
303	Benzimidazoles	1	+
304	Oximes	1	+
305	Polyethylene Terephthalates	1	+
306	Xenon Radioisotopes	1	+
307	TRPV Cation Channels	1	+
308	Receptors, Adrenergic, alpha-1	1	+
309	Baclofen	1	+
310	Fibroblast Growth Factor 2	1	+
311	Dextrans	1	+
312	Fibronectins	1	+

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