Pyruvate Dehydrogenase Complex Deficiency Disease; Ataxia with Lactic Acidosis, Type I; Lactic Acidosis with Ataxia, Type I

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Symptoms:

	Active principles	Rating	Bibliogr.
1	Pyruvate Dehydrogenase Complex	100	+
2	Pyruvate Dehydrogenase (Lipoamide)	89	+
3	Thiamine	33	+
4	Complement C2	26	+
5	Dichloroacetic Acid	25	+
6	Dihydrolipoamide Dehydrogenase	11	+
7	Dihydrolipoyllysine-Residue Acetyltransferase	10	+
8	Ketoglutarate Dehydrogenase Complex	10	+
9	Lactates	8	+
10	Thiamine Pyrophosphate	7	+
11	Pyruvates	6	+
12	Pyruvate Dehydrogenase (Lipoamide)-Phosphatase	6	+
13	Pyruvic Acid	5	+
14	Thiamin Pyrophosphokinase	5	+
15	Bicarbonates	5	+
16	Sodium Bicarbonate	5	+
17	Pyruvate Decarboxylase	4	+
18	Lactic Acid	4	+
19	Ketone Oxidoreductases	4	+
20	Phenformin	3	+
21	Glucose-6-Phosphate	3	+
22	3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)	3	+
23	Iron-Binding Proteins	2	+
24	Multienzyme Complexes	2	+
25	Acetates	2	+
26	Ataxia Telangiectasia Mutated Proteins	2	+
27	Pyruvate Carboxylase	2	+
28	Pyruvate Kinase	2	+
29	Citrate (si)-Synthase	1	+
30	Protein Kinases	1	+
31	Carbonates	1	+
32	DNA, Mitochondrial	1	+
33	Ubiquinone	1	+
34	Collagen Type I	1	+
35	L-Lactate Dehydrogenase	1	+
36	Glucose	1	+
37	Carbon Dioxide	1	+
38	NADH Dehydrogenase	1	+
39	Biotin	1	+
40	Alanine	1	+
41	Acetazolamide	1	+
42	Acetyl Coenzyme A	1	+
43	Ammonium Chloride	1	+
44	Fursultiamin	1	+
45	Oxygen	1	+
46	Protein-Serine-Threonine Kinases	1	+
47	Quinone Reductases	1	+

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