Scleroderma, Systemic; Sclerosis, Systemic

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Symptoms:

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	Active principles	Rating	Bibliogr.
1	Penicillamine	100	+
2	Interferon-beta	88	+
3	Cyclofenil	53	+
4	Aminobenzoates	45	+
5	Iloprost	42	+
6	Bleomycin	36	+
7	Dextrothyroxine	36	+
8	Latent TGF-beta Binding Proteins	34	+
9	4-Aminobenzoic Acid	32	+
10	Pronase	32	+
11	Tenascin	30	+
12	Collagen	30	+
13	Paraffin	28	+
14	Colchicine	28	+
15	Cyclophosphamide	27	+
16	Motilin	26	+
17	Riluzole	25	+
18	Cell Adhesion Molecules, Neuronal	24	+
19	Transforming Growth Factor beta	24	+
20	Methylprednisolone	24	+
21	Antibodies, Antinuclear	22	+
22	Myelin Basic Protein	22	+
23	Receptors, Endothelin	21	+
24	Peptides	21	+
25	Ribonucleoproteins	21	+
26	Complement C2	21	+
27	Beta-Globulins	21	+
28	Propylene Glycols	21	+
29	Indoleacetic Acids	20	+
30	Sphingosine	20	+
31	Transforming Growth Factor beta1	19	+
32	Carbon Monoxide	19	+
33	Collagen Type III	18	+
34	Proline	18	+
35	Sulfonamides	17	+
36	Prednisone	17	+
37	Crotonates	17	+
38	Factor XIII	17	+
39	Matrix Metalloproteinase 1	17	+
40	Myelin-Oligodendrocyte Glycoprotein	17	+
41	Epoprostenol	16	+
42	Methotrexate	15	+
43	Hydroxyproline	15	+
44	Adrenal Cortex Hormones	15	+
45	Connective Tissue Growth Factor	15	+
46	Myelin Proteins	14	+
47	4-Aminopyridine	14	+
48	Tissue Inhibitor of Metalloproteinase-1	14	+
49	Oligoclonal Bands	14	+
50	Myelin-Associated Glycoprotein	14	+
51	Prednisolone	14	+
52	RNA, Messenger	13	+
53	Collagen Type I	13	+
54	Alprostadil	13	+
55	Antibodies	13	+
56	Integrin alpha4	13	+
57	Calcitriol	13	+
58	Myxovirus Resistance Proteins	13	+
59	Gadolinium	13	+
60	Glucocorticoids	12	+
61	Antibodies, Antineutrophil Cytoplasmic	12	+
62	Penicillin G	12	+
63	Myelin Proteolipid Protein	12	+
64	Mitoxantrone	11	+
65	Receptors, Interleukin-2	11	+
66	Toluidines	11	+
67	Platelet-Derived Growth Factor	11	+
68	Receptor, Platelet-Derived Growth Factor beta	11	+
69	Hydrogen	10	+
70	Endothelin-1	10	+
71	Cuprizone	10	+
72	Receptors, Lysosphingolipid	10	+
73	Hydralazine	10	+
74	Triamcinolone	10	+
75	Cannabinoids	10	+
76	Cytokines	10	+
77	Cladribine	10	+
78	GTP-Binding Proteins	9	+
79	Superoxide Dismutase	9	+
80	Integrin alpha4beta1	9	+
81	Prostaglandins	8	+
82	Antibodies, Monoclonal, Humanized	8	+
83	Erythromycin	8	+
84	Captopril	8	+
85	Aminolevulinic Acid	8	+
86	Peptide Fragments	7	+
87	Carbon Radioisotopes	7	+
88	Neurofilament Proteins	7	+
89	Piperazines	7	+
90	HLA-DR2 Antigen	7	+
91	Interleukin-10	7	+
92	Interleukin-17	7	+
93	Antibodies, Monoclonal	6	+
94	Chemokine CXCL13	6	+
95	Interferon-gamma	6	+
96	Interferon Type I	6	+
97	Cerebrospinal Fluid Proteins	6	+
98	Matrix Metalloproteinase 9	6	+
99	Immunoglobulin G	6	+
100	Antibodies, Neutralizing	6	+
101	Autoantibodies	6	+
102	Immunoglobulins, Intravenous	6	+
103	Receptors, CXCR3	6	+
104	Receptors, Cannabinoid	5	+
105	Octreotide	5	+
106	Tumor Suppressor Proteins	5	+
107	HLA-DRB1 Chains	5	+
108	Recombinant Proteins	5	+
109	Cannabidiol	5	+
110	Acid Sensing Ion Channels	5	+
111	20-Hydroxysteroid Dehydrogenases	5	+
112	Sirolimus	5	+
113	Azathioprine	5	+
114	Glycoproteins	5	+
115	Nerve Tissue Proteins	5	+
116	Cell Adhesion Molecules	4	+
117	Dronabinol	4	+
118	Receptor, Interferon alpha-beta	4	+
119	Receptors, Antigen, T-Cell	4	+
120	Vigabatrin	4	+
121	Receptors, Lymphocyte Homing	4	+
122	Cnidarian Venoms	4	+
123	Lysophospholipids	4	+
124	Receptors, Chemokine	4	+
125	Tumor Necrosis Factor-alpha	4	+
126	Gadolinium DTPA	4	+
127	Adrenocorticotropic Hormone	4	+
128	HLA-DR Antigens	4	+
129	TOR Serine-Threonine Kinases	4	+
130	Receptors, Antigen, T-Cell, alpha-beta	4	+
131	Transfer Factor	4	+
132	Nerve Growth Factors	4	+
133	Baclofen	4	+
134	Fumarates	4	+
135	Interleukin-4	4	+
136	Interleukin-23	4	+
137	Lofepramine	4	+
138	Creatine	4	+
139	Aspartic Acid	4	+
140	Kynurenine	4	+
141	Vascular Cell Adhesion Molecule-1	4	+
142	Receptors, CCR7	4	+
143	Interleukin-12 Subunit p40	3	+
144	Vitamin D	3	+
145	Voltage-Gated Sodium Channels	3	+
146	T-Box Domain Proteins	3	+
147	B-Cell Activating Factor	3	+
148	Glial Fibrillary Acidic Protein	3	+
149	Inosine	3	+
150	Chemokines	3	+
151	Hydroxyquinolines	3	+
152	Puromycin Aminonucleoside	3	+
153	Receptor, Cannabinoid, CB2	3	+
154	Antennapedia Homeodomain Protein	3	+
155	Intercellular Adhesion Molecule-1	3	+
156	Integrins	3	+
157	Interferons	3	+
158	Threonine	3	+
159	Antigens, CD14	3	+
160	Immunoglobulins	3	+
161	alpha-Crystallin B Chain	3	+
162	Receptors, Interferon	3	+
163	Minocycline	3	+
164	Benzyl Compounds	3	+
165	Chemokine CCL5	3	+
166	Chemokine CCL2	3	+
167	Interleukin-2 Receptor alpha Subunit	3	+
168	Dithionitrobenzoic Acid	3	+
169	Receptors, CCR5	3	+
170	Tissue Inhibitor of Metalloproteinase-2	3	+
171	Forkhead Transcription Factors	3	+
172	Pentetic Acid	3	+
173	Antigens, CD45	3	+
174	Glutamic Acid	3	+
175	Neopterin	3	+
176	Matrix Metalloproteinase 7	3	+
177	Aquaporin 4	3	+
178	Antigens, CD95	3	+
179	Amines	3	+
180	gamma-Aminobutyric Acid	3	+
181	NAV1.6 Voltage-Gated Sodium Channel	3	+
182	Integrin alpha6beta1	3	+
183	Chemokine CXCL10	3	+
184	Receptors, Dopamine D5	3	+
185	Cyclohexanecarboxylic Acids	3	+
186	Osteopontin	3	+
187	STAT1 Transcription Factor	3	+
188	Chemokine CXCL11	3	+
189	Antigens, CD56	3	+
190	Transcription Factors	3	+
191	Amantadine	3	+
192	Histocompatibility Antigens Class II	3	+
193	Ciliary Neurotrophic Factor	3	+
194	Fibrillar Collagens	3	+
195	Tumor Necrosis Factor Ligand Superfamily Member 13	3	+
196	Interleukin-12 Receptor beta 2 Subunit	3	+
197	RNA, Fungal	3	+
198	Interleukin-6	3	+
199	Endocannabinoids	3	+
200	Steroids	3	+
201	Brain-Derived Neurotrophic Factor	3	+
202	Antibodies, Monoclonal, Murine-Derived	2	+
203	Immunoglobulin M	2	+
204	Antigens, CD40	2	+
205	Lymphocyte Function-Associated Antigen-1	2	+
206	Multiprotein Complexes	2	+
207	Transforming Growth Factor beta2	2	+
208	Antibodies, Blocking	2	+
209	Inosine Pranobex	2	+
210	Quinolones	2	+
211	Cobra Neurotoxin Proteins	2	+
212	Casein Kinase I	2	+
213	HLA-DP Antigens	2	+
214	Organometallic Compounds	2	+
215	Chemokines, CXC	2	+
216	Intracellular Signaling Peptides and Proteins	2	+
217	Palmitic Acids	2	+
218	Botulinum Toxins, Type A	2	+
219	Glypicans	2	+
220	Receptors, Drug	2	+
221	Interferon Regulatory Factors	2	+
222	Protein Subunits	2	+
223	Receptors, CCR1	2	+
224	Protein Isoforms	2	+
225	Matrix Metalloproteinase 2	2	+
226	Membrane Glycoproteins	2	+
227	Granzymes	2	+
228	Receptors, CCR6	2	+
229	Microfilament Proteins	2	+
230	Antigens, CD4	2	+
231	Protein Kinases	2	+
232	Receptor, Cannabinoid, CB1	2	+
233	Programmed Cell Death 1 Ligand 2 Protein	2	+
234	Prostaglandins I	2	+
235	Receptors, CXCR5	2	+
236	Antigens, CD11a	2	+
237	meta-Aminobenzoates	2	+
238	Acetates	2	+
239	Calcium-Binding Proteins	2	+
240	Interleukin-13	2	+
241	Complement C3b	2	+
242	Excitatory Amino Acid Transporter 2	2	+
243	Antigen-Antibody Complex	2	+
244	Matrix Metalloproteinases	2	+
245	B-Cell Activation Factor Receptor	2	+
246	S100 Calcium Binding Protein beta Subunit	2	+
247	Choline	2	+
248	Antigens, CD86	2	+
249	Tacrolimus Binding Protein 1A	2	+
250	Galectin 1	2	+
251	Pokeweed Mitogens	2	+
252	Nuclear Receptor Subfamily 1, Group F, Member 3	2	+
253	Chemokine CCL20	2	+
254	Receptors, Interleukin-3	2	+
255	RNA	2	+
256	Peroxynitrous Acid	2	+
257	Cholecalciferol	2	+
258	Perforin	2	+
259	Estriol	2	+
260	Coenzyme A-Transferases	2	+
261	DNA-Binding Proteins	2	+
262	DNA, Intergenic	2	+
263	Amino Acids, Diamino	2	+
264	Collagen Type XIII	2	+
265	Pemoline	2	+
266	Complement System Proteins	2	+
267	RNA Isoforms	2	+
268	Integrin alpha1	2	+
269	Immunophilins	2	+
270	Receptors, Tumor Necrosis Factor, Member 6b	2	+
271	Reactive Oxygen Species	2	+
272	Receptors, Complement 3d	2	+
273	Interleukin-2	2	+
274	Monomeric GTP-Binding Proteins	2	+
275	Lymphotoxin-alpha	2	+
276	Recombinant Fusion Proteins	2	+
277	Intermediate-Conductance Calcium-Activated Potassium Channels	2	+
278	Fas Ligand Protein	2	+
279	Interferon Regulatory Factor-1	2	+
280	Mi-2 Nucleosome Remodeling and Deacetylase Complex	2	+
281	Intercellular Signaling Peptides and Proteins	2	+
282	NF-E2-Related Factor 2	2	+
283	Sodium Tetradecyl Sulfate	2	+
284	Antibodies, Neoplasm	2	+
285	Receptors, Natural Killer Cell	1	+
286	Nitric Oxide Synthase Type II	1	+
287	Glutethimide	1	+
288	Receptors, Nerve Growth Factor	1	+
289	Acetylcarnitine	1	+
290	S100 Proteins	1	+
291	Receptors, Calcitriol	1	+
292	Uric Acid	1	+
293	Immunoglobulin kappa-Chains	1	+
294	Dextromethorphan	1	+
295	Interleukins	1	+
296	Ferrozine	1	+
297	Complement C1	1	+
298	Oncogene Proteins v-abl	1	+
299	Toll-Like Receptors	1	+
300	Glyceraldehyde-3-Phosphate Dehydrogenases	1	+
301	Iophendylate	1	+
302	Heterocyclic Compounds	1	+
303	Succinates	1	+
304	Luteolin	1	+
305	Phytohemagglutinins	1	+
306	HLA-DQ alpha-Chains	1	+
307	Amiloride	1	+
308	Arachidonic Acids	1	+
309	Pentoxifylline	1	+
310	Smad1 Protein	1	+
311	2',5'-Oligoadenylate Synthetase	1	+
312	Nifedipine	1	+
313	Receptors, Interleukin-8B	1	+
314	Protein-Serine-Threonine Kinases	1	+
315	E-Selectin	1	+
316	Tilorone	1	+
317	Polyunsaturated Alkamides	1	+
318	Trans-Activators	1	+
319	Complement C3	1	+
320	Filamins	1	+
321	Purines	1	+
322	Plant Extracts	1	+
323	Receptors, CCR2	1	+
324	Thioctic Acid	1	+
325	Receptors, Cytokine	1	+
326	Receptors, Complement	1	+
327	Receptors, Interleukin-17	1	+
328	Interleukin-1 Receptor Accessory Protein	1	+
329	Naphthalenes	1	+
330	Toll-Like Receptor 6	1	+
331	Pyrroles	1	+
332	Free Radicals	1	+
333	Nerve Growth Factor	1	+
334	Antigens, CD46	1	+
335	Thiazoles	1	+
336	Complement C9	1	+
337	Freund's Adjuvant	1	+
338	Piracetam	1	+
339	Nitric Acid	1	+
340	Intermediate Filament Proteins	1	+
341	Antigens, CD29	1	+
342	Creatinine	1	+
343	DNA Topoisomerases, Type I	1	+
344	Lipopolysaccharides	1	+
345	Trityl Compounds	1	+
346	Triazines	1	+
347	Nuclear Proteins	1	+
348	HLA-DP beta-Chains	1	+
349	Sulfhydryl Compounds	1	+
350	alpha-Cyclodextrins	1	+
351	Botulinum Toxins	1	+
352	Sodium Channels	1	+
353	Receptors, AMPA	1	+
354	Membrane Proteins	1	+
355	Cyclosporins	1	+
356	D-Aspartic Acid	1	+
357	Shaker Superfamily of Potassium Channels	1	+
358	Imidoesters	1	+
359	Alanine	1	+
360	Lithium Compounds	1	+
361	Nod1 Signaling Adaptor Protein	1	+
362	Nitric Oxide	1	+
363	Nestin	1	+
364	Phosphotransferases (Alcohol Group Acceptor)	1	+
365	Leukemia Inhibitory Factor	1	+
366	Isoleucine	1	+
367	Advanced Oxidation Protein Products	1	+
368	Oral Sprays	1	+
369	Cholestenones	1	+
370	Povidone-Iodine	1	+
371	Lysophosphatidylcholines	1	+
372	Heptanoic Acids	1	+
373	Platelet Factor 4	1	+
374	Potassium Channels, Voltage-Gated	1	+
375	Lectins	1	+
376	Receptors, Cell Surface	1	+
377	Benzoxazines	1	+
378	Antigens, CD28	1	+
379	Morpholines	1	+
380	Sulfones	1	+
381	rab GTP-Binding Proteins	1	+
382	Inflammasomes	1	+
383	Receptors, Interleukin-7	1	+
384	Extracellular Matrix Proteins	1	+
385	Semaphorins	1	+
386	Gelatinases	1	+
387	Proteome	1	+
388	STAT Transcription Factors	1	+
389	GPI-Linked Proteins	1	+
390	Proteins	1	+
391	Gangliosides	1	+
392	Interleukin-5	1	+
393	Glycophorin	1	+
394	Antigens, CD80	1	+
395	Group IV Phospholipases A2	1	+
396	Smad Proteins	1	+
397	Aminopyridines	1	+
398	Receptors, IgG	1	+
399	Benztropine	1	+
400	Carbonyl Cyanide m-Chlorophenyl Hydrazone	1	+
401	Procollagen	1	+
402	Glycine	1	+
403	Vitamin D-Binding Protein	1	+
404	Estrogen Receptor beta	1	+
405	Tetraspanins	1	+
406	Proto-Oncogene Proteins c-abl	1	+
407	Thiones	1	+
408	Activin Receptors, Type II	1	+
409	Plant Preparations	1	+
410	Oleanolic Acid	1	+
411	Matrix Metalloproteinases, Secreted	1	+
412	Linoleic Acids	1	+
413	Nitrates	1	+
414	STAT3 Transcription Factor	1	+
415	NF-kappa B	1	+
416	Polylysine	1	+
417	Ethanolamine	1	+
418	Chemokines, CC	1	+
419	Receptors, Immunologic	1	+
420	Amino Acids, Branched-Chain	1	+
421	Melatonin	1	+
422	Carrier Proteins	1	+
423	Drosophila Proteins	1	+
424	Oncogene Protein v-akt	1	+
425	Dexamethasone	1	+
426	Annexin A5	1	+
427	Receptors, Thyrotropin-Releasing Hormone	1	+
428	Acetylcysteine	1	+
429	Concanavalin A	1	+
430	Receptor, Adenosine A2A	1	+
431	Interleukin-1beta	1	+
432	Ionomycin	1	+
433	Transglutaminases	1	+
434	Macrophage Migration-Inhibitory Factors	1	+
435	CD40 Ligand	1	+
436	Contractile Proteins	1	+
437	Dantrolene	1	+
438	Lysosomal-Associated Membrane Protein 1	1	+
439	Tetracycline	1	+
440	Interleukin-7	1	+
441	Matrix Metalloproteinase 8	1	+
442	Caspase 3	1	+
443	Mechlorethamine	1	+
444	Vascular Endothelial Growth Factor A	1	+
445	Cerebrosides	1	+
446	Calcium	1	+
447	GATA3 Transcription Factor	1	+
448	Metalloendopeptidases	1	+
449	Suppressor Factors, Immunologic	1	+
450	Gonadal Steroid Hormones	1	+
451	Insulin-Like Growth Factor I	1	+
452	Thyrotropin-Releasing Hormone	1	+
453	Receptor, trkB	1	+
454	beta 2-Microglobulin	1	+
455	Relaxin	1	+
456	Cyclosporine	1	+
457	Nitrites	1	+
458	Lymphoid Enhancer-Binding Factor 1	1	+
459	Linolenic Acids	1	+
460	Calbindin 1	1	+
461	Oils	1	+
462	Antilymphocyte Serum	1	+
463	Fatty Acids, Unsaturated	1	+
464	Multienzyme Complexes	1	+
465	Lectins, C-Type	1	+
466	Metalloporphyrins	1	+
467	Fibrinolysin	1	+
468	Inositol	1	+
469	Benzhydryl Compounds	1	+
470	Receptors, Tumor Necrosis Factor, Type I	1	+
471	Interleukin-1	1	+
472	Carbon	1	+
473	Oxadiazoles	1	+
474	Peptide Hydrolases	1	+
475	Trypsin Inhibitor, Bowman-Birk Soybean	1	+
476	Vasoactive Intestinal Peptide	1	+
477	Pyrimidines	1	+
478	Apoptosis Regulatory Proteins	1	+
479	Antibodies, Anticardiolipin	1	+
480	Vitamin E	1	+
481	beta-Thromboglobulin	1	+
482	Deamino Arginine Vasopressin	1	+
483	Sialoglycoproteins	1	+
484	Green Fluorescent Proteins	1	+
485	Memantine	1	+
486	Indoles	1	+
487	Benzothiazoles	1	+
488	Tryptophan	1	+
489	Calpain	1	+
490	Chlorambucil	1	+
491	Estrogen Receptor alpha	1	+
492	Benzamides	1	+
493	Ethanol	1	+
494	Tumor Necrosis Factor Decoy Receptors	1	+
495	25-Hydroxyvitamin D3 1-alpha-Hydroxylase	1	+
496	Hepatocyte Growth Factor	1	+
497	Prostaglandins E	1	+
498	Doxycycline	1	+
499	Interleukin 1 Receptor Antagonist Protein	1	+
500	Piperidines	1	+
501	Tumor Necrosis Factors	1	+
502	Antibodies, Viral	1	+
503	Toll-Like Receptor 4	1	+
504	Collagenases	1	+
505	Carbamazepine	1	+
506	TNF-Related Apoptosis-Inducing Ligand	1	+
507	Actins	1	+
508	Quinoxalines	1	+
509	Receptors, G-Protein-Coupled	1	+
510	Vitamin B 12	1	+
511	Vaccines	1	+
512	Antibodies, Anti-Idiotypic	1	+
513	Glial Cell Line-Derived Neurotrophic Factor	1	+
514	Peptides, Cyclic	1	+
515	Receptors, Platelet-Derived Growth Factor	1	+
516	Ubiquinone	1	+
517	Biological Products	1	+
518	Tyrosine	1	+
519	Macrophage-1 Antigen	1	+
520	Antigens, CD31	1	+
521	Proto-Oncogene Proteins c-akt	1	+
522	3',5'-Cyclic-AMP Phosphodiesterases	1	+
523	Aminoimidazole Carboxamide	1	+
524	Interleukin-8	1	+
525	Receptors, Glucocorticoid	1	+
526	Valine	1	+
527	Metoclopramide	1	+
528	Fibrinopeptide A	1	+
529	Receptors, N-Methyl-D-Aspartate	1	+
530	L-Selectin	1	+
531	Albumins	1	+
532	Simvastatin	1	+
533	Lithium Carbonate	1	+
534	Cyclic Nucleotide Phosphodiesterases, Type 4	1	+
535	Cyclic N-Oxides	1	+
536	PPAR gamma	1	+
537	Rolipram	1	+
538	Lymphokines	1	+
539	Heme Oxygenase-1	1	+
540	CTLA-4 Antigen	1	+
541	Oleic Acids	1	+
542	Diterpenes	1	+
543	Mycophenolic Acid	1	+
544	Calcifediol	1	+
545	Dipeptidyl Peptidase 4	1	+
546	alpha-2-Antiplasmin	1	+
547	Immunoglobulin A	1	+

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