Cases reported "Abortion, Spontaneous"

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1/6. Reproductive and developmental hazards and employment policies.

    The task of informing workers of hazards in the workplace is seldom more difficult than with the subject of reproductive and developmental hazards. occupational health staff and physicians are faced with a paucity of relevant medical information. Workers, kept aware of the thalidomide spectre with every media report of the latest descriptive epidemiology study, are anxious to know more. Employers, knowing that few agents are regulated on the basis of reproductive hazards, are encouraged to lessen workplace exposure to all agents but need guidance from government and scientists in setting priorities. Understandable ethical and scientific limitations on human studies require researchers to study animals and cells. The difficulties of extrapolating the results of this research to humans are well known. The scientific, medical, and workplace difficulties in dealing with reproductive and developmental hazards are mirrored in the regulatory positions found in north america. Some regard fetal protection policies as sex discrimination whereas others consider such policies as reasonable. Guidelines are provided to allow employers and medical practitioners to consider this difficult problem.
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2/6. Early pregnancy loss and neonatal deaths associated with klebsiella pneumonia infection: a mini review of possible occupational health risk.

    Recurrent pregnancy loss is a disease of grave psychological and economic concern. The etiology in the vast majority of the cases is unknown or at best poorly understood. Although klebsiella pneumonia infections have been reported in humans and animals during pregnancy, there is hardly any information to indicate whether or not these infections may be responsible for early pregnancy loss. We present a review of literature and report for the first time in humans, klebsiella pneumonia infection in placenta of a 38-year-old secondary recurrent aborter (parity 2 3).
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3/6. Abortion due to infection with chlamydia psittaci in a sheep farmer's wife.

    A farmer's wife who had helped with lambing aborted spontaneously in March after a short febrile illness in the 28th week of her pregnancy. She developed disseminated intravascular coagulation post partum with acute renal failure and pulmonary oedema. Recovery was complete after two weeks of hospital care. A strain of chlamydia psittaci, probably of ovine origin, was isolated from the placenta and fetus. The patient's serum showed rising titres of antibody against chlamydia group antigen; the placental and fetal isolates; and a known ovine abortion, but not a known avian, strain of C psittaci. IgG against both ovine abortion and enteric strains of C psittaci was detected, but IgM against only an abortion strain was detected. Histological examination showed pronounced intervillus placentitis with chlamydial inclusions in the trophoblast but no evidence of fetal infection or amnionitis. Laboratory evidence of chlamydial infection was found in an aborting ewe on the farm in January and in remaining sheep and lambs in July. Doctors should recognise the possible risk to pregnant women in rural areas where chlamydial infections in farm animals are widespread.
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4/6. Human brucellosis.

    Despite advances in the control of the disease in animals, brucellosis is a zoonosis with important economic impact in the united states. It is estimated that cases of brucellosis in humans are underdiagnosed and underreported and that the disease continues to be a major human health hazard. Nine active cases of brucellosis in humans were documented in Houston, texas between June 1981 and June 1982. These cases, plus an additional case of chronic brucellosis, served as the impetus for this review of the protean manifestations of the disease in humans.
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5/6. Septic abortion associated with campylobacter fetus subspecies fetus infection: case report and review of the literature.

    In contrast to the situation in cattle, goat and sheep, campylobacter fetus subspecies fetus only rarely causes disease in humans. While a major inducer of septic abortion in animals, only a minority of clinical infections in humans are found during pregnancy. Eleven cases have so far been described in pregnant women. Clinical symptomatology is usually mild during gestation but often leads to premature labor. Here we present a multigravida with positive cultures for C. fetus who went into septic shock. She completely recovered after delivery of a C. fetus-infected fetus at 18 weeks' gestation and treatment with a combination of cephazolin and gentamicin. C. fetus infections should be suspected in patients with intensive contact with (infected) cattle or after intake of unpasteurized dairy products.
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6/6. Spontaneous abortions possibly related to ingestion of nitrate-contaminated well water--LaGrange County, indiana, 1991-1994.

    Health effects associated with ingestion of nitrate-contaminated water have included methemoglobinemia (i.e., blue baby syndrome) in infants and spontaneous abortions in laboratory animals and livestock; however, only one study in humans has reported an association between increased methemoglobin levels and spontaneous abortion. During March 1993, the LaGrange County (indiana) Health Department (LCHD) identified three women who reported a total of six spontaneous abortions during 1991-1993 and who resided in proximity to each other; each had obtained drinking water from nitrate-contaminated private wells in LaGrange County (1995 population: 29,350). LCHD was subsequently notified about a fourth woman from another part of the county who had had two spontaneous abortions after she had moved into a new home with a nitrate-contaminated private well. This report summarizes the investigations of these reports by LCHD, which indicate the need for further assessment of a possible relation between ingesting nitrate-contaminated water and spontaneous abortion.
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