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1/289. Organ-preserving surgery of renal cell carcinoma: report of four cases.

    Authors removed the renal tumour of four patients by means of resection in an organ-preserving manner. Of the four patients, one had bilateral carcinoma. The right-sided carcinoma of this patient was removed by resection while the other kidney was removed radically, by transabdominal approach. In three of the four cases which were in the process of stages T1 and N0M0, organ-preserving surgery was performed in the presence of intact opposite kidneys. Authors point out the fact that the resection method might be indicated even in the case of early (T1) stage tumours with intact opposite side kidneys. Furthermore, they do not recommend the enucleation of renal carcinomas for the surgical treatment of kidney tumours, since experimental studies have proved that these tumours can be transferred into the parenchyma of the kidney through the pseudocapsule of the tumour. ( info)

2/289. Recurrent clear cell carcinoma of the ovary changing into producing parathyroid hormone-related protein (PTH-rP) with hypercalcemia.

    We experienced the case of a clear cell carcinoma of the ovary arising from an endometrial cyst, which started to produce parathyroid hormone-related protein (PTH-rP) in a recurrent tumor, thus inducing hypercalcemia. Using immunohistochemical analysis, we demonstrated that the primary carcinoma was immunonegative for PTH-rP, but that the recurrent carcinoma was strongly immunopositive for PTH-rP. ( info)

3/289. Papillary clear cell adenocarcinoma of the groin arising from endometriosis.

    A 67-year-old woman presented with rapidly enlarging right anterior thigh mass. Clinical impression was of a primary sarcoma, but the histologic analysis of an incisional biopsy specimen showed adenocarcinoma with clear cell differentiation. Initially thought to be a metastasis, the malignant tumor appears to have arisen from extraabdominal endometriosis of the right groin. This case shows clinical, radiographic, and histologic findings that may help the orthopaedic surgeon recognize an unusual complication of extrapelvic endometriosis. ( info)

4/289. Late recurrence of a uterine clear cell adenocarcinoma confined to an endometrial polyp: case report.

    A patient with an endometrial clear cell adenocarcinoma confined to a polyp developed recurrent disease in the abdomen and pelvis four years following hysterectomy. Treatment issues related to this uncommon clinical situation are discussed. ( info)

5/289. Clear cell carcinoma arising in a cesarean section scar endometriosis: a case report.

    endometriosis of a surgical scar is rare and occurs mainly when a hysterectomy or cesarean section was performed. We describe a 54-year-old woman with a large suprapubic mass as a definite case of a endomerioid carcinoma developing within the scar endometriosis following cesarean section. Scar endometriosis, as well as endometriosis at other sites, can turn malignant. Endometrioid carcinoma is the most common histological pattern of malignant tumor arising in endometriosis. But clear cell carcinoma is very unusual. A case of primary clear cell carcinoma in endometriosis of a cesarean section scar is described. To the best of our knowledge, this is the first documented case of endomerioid carcinoma developing within the scar endometriosis in korea. ( info)

6/289. Ovarian carcinoma with fistula formation to the sigmoid colon and ileum: report of a case.

    We describe herein an extremely rare case of clear cell type ovarian carcinoma resulting in fistula formation into the colon and intestine. The patient was a 61-year-old woman in whom a large tumor with extravasation from the sigmoid colon was found by barium enema examination. The tumor was preoperatively diagnosed as left ovarian cancer by angiography which showed the tumor feeder arising from the left ovarian and uterine arteries. ( info)

7/289. Simultaneous contralateral testicular metastasis from a renal clear cell carcinoma.

    The case of a 66-year-old male with a right renal cell carcinoma and a left testicular mass is reported. Radical nephrectomy and contralateral orchidectomy were performed. histology revealed a metastasis of the renal cell carcinoma of clear cell type into the left testis. The patient died seven months post-operatively of disseminated lung metastases. The case demonstrates the multi-ocular metastatic potential of renal cell carcinoma. ( info)

8/289. blindness as a consequence of a paraneoplastic syndrome in a woman with clear cell carcinoma of the ovary.

    BACKGROUND: paraneoplastic syndromes are rare conditions associated with cancer that result in serious disease states at unique sites. In 1982, a report of bilateral diffuse uveal melanocytic proliferation associated with nonocular cancers which resulted in blindness was reported. We present a case of a woman with recurrent ovarian cancer who developed this paraneoplastic syndrome. CASE: A 55-year-old woman had been diagnosed in 1990 with an ocular melanoma of her right eye and in 1994 with clear cell carcinoma of the ovary. With recurrence of ovarian cancer, new eye lesions were identified in both eyes. After enulcleation of her right eye, an ocular melanoma and diffuse bilateral melanocytic proliferation (BDUMP) were found. The sight in her left eye continued to deteriorate as other signs of BDUMP occurred in the eye. Within 1 month of diagnosis, the patient was blind. She subsequently succumbed to progression of ovarian cancer. CONCLUSION: Recurrent ovarian cancer is usually an intraabdominal disease that results in gastrointestinal dysfunction. This case illustrates a rare paraneoplastic syndrome associated with ovarian cancer that mimics metastatic disease to the eye, but has a different pathophysiology. ( info)

9/289. Tumor-to-tumor metastasis to follicular variant of papillary carcinoma of thyroid.

    OBJECTIVE: To describe and document tumor-to-tumor metastases in the thyroid gland. methods AND RESULTS: In this series we describe 3 cases of tumor-to-tumor metastasis in which the recipient tumor was a follicular variant of papillary thyroid carcinoma. The donor tumors and sites were small cell carcinoma of the lung, neuroendocrine carcinoma probably of pancreatic origin with initial presentation as liver metastasis, and clear cell carcinoma of the kidney with metastasis to liver and pancreas. The donor tumor cells infiltrated the substance of the follicular variant of papillary thyroid carcinoma, the nontumorous thyroid parenchyma, and the lymphovascular spaces. Small cell carcinoma and neuroendocrine carcinoma showed positive reactivity for neuroendocrine markers and were negative for thyroglobulin and calcitonin. The follicular variant of papillary thyroid carcinoma showed positivity with thyroglobulin and cytokeratin 19. CONCLUSIONS: Although tumor-to-tumor metastases in thyroid gland are exceedingly rare, one should be aware of this phenomenon as the metastatic lesion may simulate a thyroid primary. history of a previous tumor and immunohistochemical stains can be helpful in distinguishing between primary and metastatic thyroid neoplasms. ( info)

10/289. A case report on two primary malignancies of the ovary and kidney.

    Multiple primary malignant tumors in the same patient are very rare. Moreover, cases with primary ovarian and renal cell carcinoma in the same patient is an extremely rare phenomenon. In this report, a case with these two primaries is described. Concomitantly, some data suggesting a relationship of these primaries with the hypothesis of hormone dependency of renal cell carcinoma is presented. ( info)
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