Cases reported "Adenocarcinoma, Scirrhous"

Filter by keywords:



Filtering documents. Please wait...

1/4. Corrosive gastritis mimicking linitis plastica carcinoma.

    A 59-year-old female with depressive tendencies was admitted suffering from hematemesis and abdominal pain, two hours after ingestion of an unknown amount of toilet bowl cleaner (hydrochloric acid, pH 1.0). A barium study 24 days after ingestion revealed rigid narrowing and granulation of the entire stomach. The esophagus and duodenum were normal. The radiographic results were similar to those obtained for linitis plastica carcinoma of the stomach, but biopsy specimens of the stomach revealed no cancer cells. A total gastrectomy was performed about two months after ingestion to relieve the persistent feeling of nausea. Specimens revealed a rigid and thickening lining and a denuded mucosal surface of the stomach. The cut surface of the specimen showed a remarkable fibrous thickening of the submucosal layer. Microscopic examination failed to reveal a normal mucosal layer except in a narrow area of the fornix, and remarkable fibrosis of the submucosal lining was noted. No cancer cells were found. Corrosive gastritis has a linitis plastica appearance with a predilection for the antrum. Radiological examination revealed the very rare manifestation of a rigid narrowing of the whole stomach mimicking linitis plastica type cancer.
- - - - - - - - - -
ranking = 1
keywords = esophagus
(Clic here for more details about this article)

2/4. Gastric linitis plastica with metastases to the colon: a mimic of Crohn's disease.

    A 60-year-old woman had progressive lower abdominal pain, nonbloody diarrhea, and weight loss, followed by severe epigastric pain and dysphagia. Radiographic evaluation of the colon showed segmental strictures which were interpreted as Crohn's disease. Medical treatment was not helpful. Neither gross endoscopic appearance nor multiple biopsies of the esophagus, stomach, and colon were diagnostic. Finally, laparotomy with full-thickness biopsies of the stomach and colon revealed linitis plastica. The clinician should be alert to colonic metastases from gastric linitis plastica, for it can produce focal or segmental strictures, mimicking more common colonic diseases such as Crohn's disease. A full-thickness biopsy is often necessary for a firm diagnosis. We review the literature on this occurrence, highlighting the clinical and radiologic spectrum, as well as the organ systems most often affected when gastric linitis plastica metastasizes.
- - - - - - - - - -
ranking = 1
keywords = esophagus
(Clic here for more details about this article)

3/4. linitis plastica of the esophagus.

    A 62-yr-old woman was evaluated for a 2-wk history of regurgitation and weight loss. Radiologic studies demonstrated a stenotic region in the distal third of the esophagus. Multiple endoscopic biopsies were nondiagnostic. esophagectomy and esophagogastrostomy revealed a diffusely infiltrating adenocarcinoma ("linitis plastica") of the distal esophagus, sparing the gastroesophageal junction and stomach. Despite the absence of metastatic disease at laparotomy, the patient developed metastases unresponsive to chemotherapy. The pathologic, radiographic, and endoscopic findings are consistent with primary linitis plastica of the esophagus.
- - - - - - - - - -
ranking = 7
keywords = esophagus
(Clic here for more details about this article)

4/4. linitis plastica carcinoma of the esophagus.

    Two patients, 60 and 62 years old, were admitted with progressive dysphagia and weight loss of 8 to 12 weeks duration. Radiographic studies revealed an area of stenosis in the lower third of the esophagus in both cases. Endoscopic and biopsy findings established the diagnosis of a neoplasm, with malignant signet ring cells infiltrating the mucosa. Partial esophagogastrectomy in both cases disclosed an infiltrative adenocarcinoma of the lower esophagus, without involvement of the gastroesophageal junction. One of the patients had metastases to regional lymph nodes; the other patient has no clinical evidence of recurrence 14 months after surgery. Endoscopic, radiologic, and pathologic findings are consistent with the diagnosis of linitis plastica of the esophagus.
- - - - - - - - - -
ranking = 7
keywords = esophagus
(Clic here for more details about this article)


Leave a message about 'Adenocarcinoma, Scirrhous'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.