Cases reported "Anemia, Neonatal"

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1/16. Fetal complication after external cephalic version at term: case report and literature review.

    We report a case of fetal distress following external cephalic version at term, which resulted in delivery by emergency cesarean section of an anemic, acidemic infant. The characteristics of the fetal heart rate tracing, the clinical findings, and a positive Kleihauer-Betke test after delivery suggest that fetomaternal hemorrhage or placental abruption was the most likely cause of the fetal distress. We review the incidence of the reported fetal complications after external version.
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ranking = 1
keywords = fetomaternal
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2/16. Management of severe neonatal anemia due to fetomaternal transfusion.

    Three cases of severe neonatal anemia due to fetomaternal transfusion are reported. The key features that lead to early diagnosis were the maternal history, fetal monitoring, the clinical and laboratory findings of anemia, and a negative coombs test. Diagnosis was confirmed by a rapid Kleihauer-Betke test. A partial exchange transfusion was performed in two of the three neonates with rapid clinical and hematological improvement. As two patients showed signs of heart decompensation, a partial exchange transfusion was performed with good success. In patients presenting with severe subacute or chronic anemia and heart failure, a partial exchange transfusion may be preferable to that of simple transfusion associated with diuretics.
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ranking = 107.47206109274
keywords = fetomaternal transfusion, fetomaternal, transfusion
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3/16. subcutaneous fat necrosis of the newborn associated with anemia.

    subcutaneous fat necrosis (SFN) of the newborn characteristically affects full-term infants who have experienced perinatal distress, such as hypothermia, obstetric trauma, or asphyxia. We report a newborn who had pallor, deep breathing, and severe anemia immediately after birth. She developed SFN on the fourth postnatal day. Her condition improved after blood transfusions and the skin lesions resolved in 6 weeks. This appears to be the first report of SFN associated with anemia.
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ranking = 0.0017689296017881
keywords = transfusion
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4/16. Sickle-cell disease not identified by newborn screening because of prior transfusion.

    erythrocyte transfusion can impair detection of sickle-cell disease, galactosemia, or biotinidase deficiency with newborn screening. We report on 4 infants with SCD in whom delayed diagnosis was associated with neonatal transfusion. In 2 cases, the initial newborn screening showed no hemoglobin S. In no case was the recommended screening >/=120 days from the last transfusion obtained. Two children had significant SCD-related morbidity before diagnosis.
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ranking = 0.012382507212517
keywords = transfusion
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5/16. Hb Dartmouth [alpha66(E15)Leu-->Pro (alpha2) (CTG-->CCG)]: a novel alpha2-globin gene mutation associated with severe neonatal anemia when inherited in trans with Southeast Asian alpha-thalassemia-1.

    We report a novel mutation at alpha66(E15)Leu-->Pro (alpha2) (CTG-->CCG), that we have named Hb Dartmouth for the medical center at which the patients were cared for, in monozygotic twins who also inherited the Southeast Asian alpha-thalassemia-1 deletion. The mother, of Khmer ancestry, is heterozygous for alpha-thalassemia-1. The father, who is of Scottish-Irish ancestry, is a silent carrier of the codon 66 mutation. The twins had severe neonatal anemia requiring transfusion.
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ranking = 0.0017689296017881
keywords = transfusion
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6/16. Postmortem diagnosis of diamond-Blackfan anemia.

    diamond-Blackfan anemia (DBA) is a rare etiology for congenital anemia, but this diagnosis should be considered when aregenerative hypoplastic anemia occurs in infancy. A term infant girl received a red blood cell transfusion at birth for neonatal anemia (hemoglobin 75 g/L) initially attributed to abruptio placentae. There were no additional investigations. Hemoglobin gradually decreased during the first 4 weeks of life, leading to severe anemia and death despite transfusions. A postmortem diagnosis of DBA was made by extraction of dna collected on blood filter paper showing a deletion in RPS19 gene. Neonatal anemias should be carefully investigated and close follow-up should be performed during the first months of life, even if there is an obvious hemorrhagic etiology.
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ranking = 0.0035378592035762
keywords = transfusion
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7/16. Severe hemolytic disease of the newborn due to anti-Cw.

    BACKGROUND: Pregnancies complicated by rh isoimmunization have decreased significantly since the widespread use of Rh immune globulin. Uncommon red blood cell antigens have therefore become more clinically evident. We report a case of anti-Cw immunization that resulted in severe fetal anemia that required multiple transfusions. CASE: A 28-year-old multigravida presented to our service at 18 weeks of gestation with her fourth pregnancy. Her pregnancy was complicated by anti-Cw isoimmunization that resulted in severe fetal anemia requiring in utero fetal blood transfusions. CONCLUSION: While previous reports recommend only postpartum surveillance when Cw isoimmunization is present, we report a case resulting in severe fetal anemia.
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ranking = 0.0035378592035762
keywords = transfusion
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8/16. Clinico-pathologic conference: fetomaternal transfusion.

    A case is presented of a newborn infant with severe fetomaternal transfusion, which resulted in profound anemia and early demise.
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ranking = 107.46498537433
keywords = fetomaternal transfusion, fetomaternal, transfusion
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9/16. Determination of serum ferritin in the evaluation of iron depletion and iron over load in chronic twin-to-twin transfusion syndrome.

    In two pairs of twins with twin-to-twin transfusion syndrome serum ferritin levels were determined in order to estimate body storage of iron. serum ferritin levels in the donor twins were found to be markedly lower than in the recipients and were below the lower limit found in normal neonates. One of the recipients was hydropic. His ferritin level was elevated far above the upper limit of normal. These findings support the hypothesis that in chronic twin-to-twin transfusion, depletion of iron stores occurs in the donor while the recipient suffers from iron overload. Determination of ferritin levels may be useful in the investigation of the twin-to-twin transfusion syndrome.
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ranking = 0.012382507212517
keywords = transfusion
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10/16. Severe fetomaternal hemorrhage. A report of four cases.

    Four cases of severe fetomaternal hemorrhage (FMH) presented with severe anemia and signs of circulatory failure. One of the patients developed the syndrome of persistent fetal circulation. The diagnosis of FMH was confirmed in all using Kleihauer-Betke tests, which demonstrated abundant fetal erythrocytes in the maternal circulation. Three infants survived after prompt volume replacement and correction of anemia. The only fatality was related to an underlying chromosomal disorder. The majority of reported neonatal deaths due to FMH have occurred when shock was the presenting manifestation.
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ranking = 5
keywords = fetomaternal
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