11/35. Cardiovascular involvement in Crohn's disease in the absence of ankylosing spondylitis.We describe a patient who had aortic regurgitation associated with Crohn's disease in the absence of ankylosing spondylitis. aortitis and aortic insufficiency are fairly uncommon in Crohn's disease. The patient required aortic valve replacement because of severely uncoated cusps secondary to inflammation of the aortic wall and aortic valve. There was a saccular formation just above the right non-coronary commissure. This sac was closed with a pericardial patch. Pledgeted sutures were used for implantation of the prosthetic valve to avoid periprosthetic leakage. The right coronary ostium had narrowed due to aortic wall thickening. A right internal thoracic artery to right coronary artery bypass was done since there was no necessity for proximal anastomosis.- - - - - - - - - - ranking = 1keywords = artery (Clic here for more details about this article) |
12/35. Takayasu aortitis with acute dissection and hemopericardium.We report a case of a 57-year-old woman with an unremarkable past medical history who presented to the emergency department with maxillary pain that later radiated to the chest. She died less than 12 h after admission. CT findings were consistent with ascending aorta dissection with hemopericardium. autopsy revealed a tear immediately proximal to the ostium of the brachiocephalic artery and a dissecting flap with false lumen, rupture, and hemopericardium. Histologically, there was a zonal medial necrosis with surrounding chronic inflammation, focal destruction of the media, and fibrosis of the intima and adventitia. A diagnosis of granulomatous necrotizing aortitis of Takayasu type was made. This case demonstrates a rare example of aortitis underlying aortic dissection and emphasizes the need for careful histologic examination in cases of aortic root disease.- - - - - - - - - - ranking = 0.5keywords = artery (Clic here for more details about this article) |
13/35. Regression of the left main trunk lesion by steroid administration in Takayasu's aortitis.A 62-year-old man with unstable angina due to severe narrowing of the left main trunk (LMT) was examined. Emergency bypass surgery was performed with an internal mammary artery graft, instead of a saphenous vein graft, because of the thickened, edematous ascending aorta. Postoperative coronary angiography showed the lesion of the LMT markedly regressing. Presumably, this stenotic lesion of the LMT was caused by active aortitis and was partially reversible by steroid administration both during and after surgery. Steroid therapy can be added to the list of treatments for cases of LMT disease associated with Takayasu's aortitis, if signs of active inflammation are present.- - - - - - - - - - ranking = 0.5keywords = artery (Clic here for more details about this article) |
14/35. The inflammatory abdominal aortic aneurysm and coronary artery disease. Case report and review.Inflammatory abdominal aortic aneurysm (IAAA) is defined as an unusually thickened aneurysmatic wall, encircled by a wide dense perianeurysmal and/or retroperitoneal fibrosis with adjacent tissues adhesion, and is now considered as an extreme shape of the common phlogistic process involved in atherosclerotic plaque formation. Latest studies demonstrated that inflammation plays an important role in coronary disease and in other atherosclerosis manifestations. We introduce the clinical case of a patient with IAAA who developed an acute myocardial infarction 6 months after the surgical procedure on the aorta. Through a literature review about IAAA we stress the clinical usefulness of the inflammatory markers as independent predictors in management of patients with coronary disease and we present the hypothesis, related to the introduced case, of an advanced coronary disease, aggravated or clinically revealed after the cytokine storm related to important localized inflammatory engagements or great vascular surgery treatments.- - - - - - - - - - ranking = 2keywords = artery (Clic here for more details about this article) |
15/35. Abnormal accumulation of [18F]fluorodeoxyglucose in the aortic wall related to inflammatory changes: three case reports.We present 3 cases with abnormal accumulation of FDG in the aortic wall. Their clinical manifestations were vague or asymptomatic, and laboratory data were consistent with inflammatory reaction. These 3 patients were diagnosed with takayasu arteritis, inflammatory aortic aneurysm (IAA), and retroperitoneal fibrosis (RF), respectively. FDG-PET and CT images showed the intense FDG uptake corresponding to the arterial walls and/or the soft tissue density surrounding the artery. It was deduced that FDG was probably taken up by inflammatory cells which infiltrated the arterial walls and/or the soft tissue mass. These cases indicated that FDG-PET is a useful method for localization of inflammatory lesion in patients with unspecific clinical findings and laboratory data.- - - - - - - - - - ranking = 0.5keywords = artery (Clic here for more details about this article) |
16/35. Isolated bilateral coronary ostial stenosis--an uncommon presentation of aortoarteritis.Aortoarteritis presenting with isolated bilateral coronary artery ostial stenosis is a serious but rare condition. This letter emphasizes on a very atypical presentation of aortoarteritis and also distinct but unusual form of angiographic findings involving total occlusion of left main coronary artery from the ostium and tight ostial right coronary artery stenosis that had a fulminant disease course.- - - - - - - - - - ranking = 1.5keywords = artery (Clic here for more details about this article) |
17/35. Cogan's syndrome with aortitis, aortic regurgitation, and aortic arch vessel stenoses.Cogan's syndrome of interstitial keratitis and vestibuloauditory dysfunction is rare. Systemic vasculitic manifestations occur, and 10% of patients with this syndrome have aortic valvular disease. A patient with Cogan's syndrome is presented who had aortitis of the ascending thoracic aorta, severe aortic valve regurgitation, orificial stenosis of the right coronary artery, and orificial stenoses of all three aortic arch vessels. Histopathology confirmed aortitis. aortic valve replacement combined with coronary and aortic arch vessel reconstruction was required for correction.- - - - - - - - - - ranking = 0.5keywords = artery (Clic here for more details about this article) |
18/35. Aneurysm in the sequestrated lung and aortitis associated with the malignant rheumatoid arthritis.A scar phase of rheumatoid aortitis and aneurysms in the sequestrated lung with a lesion continuous to an aortic lesion was found in autopsy specimens from a 50 year-old-woman, who had suffered from generally disseminated carcinoma of the breast. The aorta revealed a scar phase of granulomatous panaortitis continuously from the ascending to the descending thoracic aorta. The media and adventitia of the aorta were largely replaced by scar tissue, although the aortic valve was spared. The systemic arteries in the sequestrated lung were destroyed completely by the necrotizing angiitis and showed saccular aneurysm filled with organizing fibrin thrombus. The pulmonary artery was intact. These findings suggest that the saccular aneurysm in the sequestrated lung was produced by necrotizing angiitis, in association with rheumatoid aortitis.- - - - - - - - - - ranking = 0.5keywords = artery (Clic here for more details about this article) |
19/35. Surgical treatment of non-specific inflammatory arterial aneurysms.In the past thirty years, fifty arterial aneurysms due to non-specific inflammation in forty-two patients were operated on. Twenty-five patients were males and 17 were females; their average age was 38 years. The majority of the aneurysms were located in the abdominal aorta, common carotid artery, and femoral artery. Clinical diagnoses were Takayasu's disease (11), Behcet's disease (3), giant cell aortitis (2), and systemic lupus erythematosus (1). The other twenty-five cases were of undetermined etiology. There were fourteen cases of rupture, and long-term steroid administration in five cases was suspected of playing a major role in inducing this grave sequel. Aneurysmectomy with arterial reconstruction was performed on 37 cases. Various histological findings of inflammation were observed in the resected specimens. The suture aneurysms occurred in eight cases in the late period. Surgical care of non-specific inflammatory arterial aneurysms was judged to be more difficult than that of atherosclerotic aneurysms.- - - - - - - - - - ranking = 1keywords = artery (Clic here for more details about this article) |
20/35. fatal outcome of aortocoronary bypass grafting in a 62-year-old man with unsuspected coronary arteritis.A 62-year-old man was admitted to our hospital with unstable angina. The coronary arteriography showed the occlusion of the left anterior descending artery and other stenotic lesions. The patient underwent an aortocoronary bypass operation, but unfortunately he did not survive. Surprisingly, the necropsy revealed him to be affected by an inflammatory process, involving the aorta and the coronary arteries. According to the clinical history and examination, the findings at necropsy and the histologic picture, the diagnosis of Takayasu's arteritis appears the most probable. Coronary arteritis has to be considered as a possible etiology of ischemic symptoms also in subjects who appear affected by typical atherosclerotic ischemic heart disease.- - - - - - - - - - ranking = 0.5keywords = artery (Clic here for more details about this article) |
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