Cases reported "Asthma, Exercise-Induced"

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1/15. Beneficial effect of combination therapy with ozagrel and pranlukast in exercise-induced asthma demonstrated by krypton-81 m ventilation scintigraphy--a case report.

    INTRODUCTION: We evaluated the effect of combination therapy with thromboxane a2 synthesis inhibitor and leukotriene receptor antagonist in a patient with exercise-induced asthma using krypton-81 m ventilation scintigraphy. CLINICAL PICTURE: In a patient with exercise-induced asthma, we found exercise-induced abnormalities of respiratory function test and ventilation scintigraphy, and increases in plasma concentrations of thromboxane b2 and leukotriene c4 with exercise. TREATMENT: A thromboxane a2 synthesis inhibitor (ozagrel) and a leukotriene receptor antagonist (pranlukast) were prescribed. OUTCOME: After treatment for 2 weeks, abnormalities of respiratory function test and ventilation scintigraphy improved. CONCLUSIONS: The combination therapy with ozagrel and pranlukast might be useful for the relief of symptoms in patients with exercise-induced asthma, and krypton-81 m ventilation scintigraphy could be a useful tool for visible evaluation of treatment.
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2/15. exercise-induced asthma (EIA) after walking: a case report.

    A case in which exercise-induced asthma (EIA) was provoked at an intensity of less than 100 beats/min is discussed. EIA was provoked by a 12-minute walk test. Earlier tests using walking on other subjects had not produced such a result. It is therefore vital to teach asthmatics to monitor their pulmonary response at regular intervals to avert serious attacks in activities of daily living.
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3/15. Effects of the biopsychosocial approach (BPSA) on exercise-induced asthma (EIA).

    The Biopsychosocial Approach (BPSA) is a treatment program for allergic patients which includes therapy for psychological, behavioral and social factors as well as for physical problems, following basic principles of psychoneuroimmunology. BPSA was applied to patients with bronchial asthma and favorable results were obtained. The mechanism of the therapeutic effects of BPSA included normalization of the patient's autonomic nervous function, levels of blood histamine, and circadian rhythm of lymphocyte activity. BPSA was also used in patients with exercise induced asthma (EIA) and the same parameters were evaluated. Results showed that patients with EIA recovered physiological homeostasis after BPSA therapy normalized blood levels of histamine and substance p (SP), skin reactions to histamine and SP, and autonomic nervous function. We conclude that BPSA is effective for treating patients with EIA.
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4/15. cough-variant asthma in children and adults: case reports and review.

    Two cases of cough-variant asthma are presented, one in an adult and one in a child. We discuss the diagnosis, treatment, and course of this common, yet often unrecognized entity. The keys to diagnosis are a typical history, clinical suspicion, and subsequent response to bronchodilator therapy. Treatment of cough-variant asthma is no different from that of classic asthma.
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5/15. exercise-induced anaphylaxis: improvement after removal of amalgam in dental caries.

    We present a case of exercise-induced anaphylaxis with improvement following the removal of dental amalgam. Although her symptoms were unresponsive to various kinds of therapy until removal of the amalgam, her symptoms related to exercise improved remarkably after the removal. The increase in plasma histamine levels for exercise provocation test also improved. This suggests that sensitivity to metals might cause exercise-induced asthma in some patients.
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6/15. Aortic arch anomaly presenting as exercise-induced asthma.

    We present the case of a young woman with a right aortic arch who first became symptomatic when she began a vigorous exercise program. Her symptoms were very suggestive of exercise-induced bronchospasm. Her flow-volume curves, however, showed evidence of variable intrathoracic large airways obstruction. A magnetic resonance imaging scan confirmed the presence of severe tracheal narrowing caused by her right aortic arch.
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7/15. exercise-induced "asthma" as a presentation of bronchial carcinoid.

    exercise-induced wheezing developed in a previously healthy 14-year-old boy. Chest radiographs revealed hyperlucency of the left lung. Bronchial tomography and bronchoscopy revealed a mass in the left mainstem bronchus, identified as a carcinoid tumor after surgical excision. The patient is now asymptomatic. exercise-induced wheezing as the sole manifestation of this tumor has not been previously reported.
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8/15. Bronchial asthma in servicemen--a personal view.

    This paper is a review of 59 serving male officers and soldiers with bronchial asthma who attended the Chest Clinic at the Cambridge Military Hospital during a defined period of time and who had been under the care of the author for periods of up to six years. The patterns of presentation, management, progress and outcome are described. exercise induced asthma is seen as the biggest problem for servicemen often with otherwise mild asthma, and there is evidence that potential recruits are still not being adequately assessed. In younger men, exercise associated disability is an early symptom, but older individuals tend to divide into one group with early exercise related problems and another who remain able to exercise at least for a time. Response to prophylactic therapy is good, but it is often difficult to eliminate exercise induced wheeze in military training and relapse is common when prophylaxis is withdrawn. The effect of this on medical category is described and some of the implications are discussed.
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9/15. Changes in angiotensin-converting enzyme activity and angiotensin i level in asthmatic and healthy children after submaximal physical work.

    The changes in angiotensin-converting enzyme activity and serum angiotensin i levels have been studied in 16 controls subjected to submaximal physical work. Baseline (Pre-exercise) angiotensin i levels were identical in both groups. Physical exercise caused an elevation that was more marked in the asthmatic group than in the control group. The activity of serum angiotensin-converting enzyme differed in the two groups even before physical exercise, the asthmatic children having exhibited an activity level significantly lower than that of the healthy controls. after submaximal work, the enzyme activity increased in healthy subjects but decreased in asthmatic children.
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10/15. Upper airway obstruction presenting as exercise-induced asthma.

    A patient presented with a ten-year history of exercise-induced wheezing. After trials of metaproterenol and cromolyn failed to improve her symptoms, she was observed during exercise. She proved to have inspiratory stridor caused by collapse of the posterior aryepiglottic folds over the vocal cords during inspiration only following exercise. Symptoms primarily improved with physical conditioning. Further improvement came after treatment of her chronic rhinitis and post-nasal drip with a steroid nasal spray.
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