1/7. Atrophie blanche-like scarring after pulsed dye laser treatment.Pulsed dye laser treatment is well established for the treatment of port-wine stains and other vascular skin lesions. Although hyperpigmentation is quite common, other side effects such as hypopigmentation and atrophic scarring occur infrequently, and hypertrophic scarring is rare.- - - - - - - - - - ranking = 1keywords = hypopigmentation (Clic here for more details about this article) |
2/7. dermabrasion: a curative treatment for melasma.Melasma is fairly common in Asian patients with a dark skin tone. It has long been known for its recalcitrance to any form of treatment. The objective of this article is to propose mechanical dermabrasion as a curative treatment for this entity. Five hundred and thirty-three patients with melasma were treated by mechanical dermabrasion using a rotatory diamond fraise. Four hundred and ten patients were available for long-term follow-up (mean follow-up time 5 years, range 1-9 years). Out of 410 patients, 398 (97%) achieved persistent clearance of melasma; in the remaining cases, there was partial recurrence after initial clearance. The common temporary sequelae were postoperative erythema or hyperpigmentation, pruritus, and milia formation. Two patients developed hypertrophic scars, one on the upper lip and one on the jawline, and one patient had permanent hypopigmentation on the forehead. In conclusion, mechanical dermabrasion is a relatively safe and highly effective means for curing melasma.- - - - - - - - - - ranking = 1keywords = hypopigmentation (Clic here for more details about this article) |
3/7. Retinochoroidal atrophy in two adult patients with angelman syndrome.We describe a new ocular finding, retinochoroidal atrophy (RCA), associated with optic disk paleness in two adult patients with angelman syndrome (AS) due to maternal 15q11-13 deletion. The ocular involvement described in children with AS consists iris and choroids hypopigmentation due to loss of function of one copy of P gene involved in maternal deletion. The loss of one copy of the same gene of paternal origin leads to a similar ocular phenotype as in prader-willi syndrome (PWS). However to our knowledge, RCA has never been described before in PWS, suggesting that other maternally expressed genes, particularly UBE3A, could be responsible for the retinal changes observed in the adult AS phenotype. Although, further investigations would be necessary to better understand the role of the UBE3A in the retina, the findings reported here should prompt a systematic ophthalmologic evaluation adult patients with AS in order to establish the real incidence of RCA and prevent further disability in these patients.- - - - - - - - - - ranking = 1keywords = hypopigmentation (Clic here for more details about this article) |
4/7. Unilateral congenital linear atrophoderma of the leg.We report an infant with depressed, hypopigmented, linear plaques of congenital onset on the lower extremity. The lesions were asymptomatic and the child was otherwise healthy. Despite the clinically obvious change in skin texture and color, histopathologic changes were subtle: a biopsy specimen showed hypopigmentation and a decrease in elastic fibers in the papillary and upper reticular dermis. Diagnoses considered included various congenital syndromes, idiopathic atrophoderma of Pasini and Pierini, and especially, linear atrophoderma of Moulin. However, because of the significant clinical and histopathologic differences when compared to the aforementioned entities, our patient appears to have a unique presentation of congenital linear atrophoderma.- - - - - - - - - - ranking = 1keywords = hypopigmentation (Clic here for more details about this article) |
5/7. Fractional photothermolysis for treatment of poikiloderma of civatte.Poikiloderma of Civatte refers to a change in the skin where there is atrophy, hyper- and hypopigmentation, and dilation of fine blood vessels (telangiectasia). These alterations often cause cosmetic disfigurement, most commonly in middle-aged or elderly women with a fair complexion. Several treatment modalities, based on the theory of selective photothermolysis, including argon lasers, KTP lasers, pulsed dye lasers, and intense pulsed light devices, have been used to treat this condition in the past. Clinical experience has shown that complete clearing is difficult to achieve. Moreover, depending on the modality used, adverse effects, such as scarring with irregular hypopigmentation, post-inflammatory hyperpigmentation, post-treatment purpura, mottled appearance, crusting, and erythema, have been reported. Multiple sessions with these treatments are usually necessary to obtain optimal clearing.- - - - - - - - - - ranking = 2keywords = hypopigmentation (Clic here for more details about this article) |
6/7. Perilesional linear atrophy and hypopigmentation after intralesional corticosteroid therapy. Report of two cases and review of the literature.We report on the cases of two patients in whom linear perilesional hypopigmentation and atrophy developed after intralesional injection of corticosteroids for treatment of keloids. Evaluation of our patients and the previously reported cases showed that perilesional linear atrophy or hypopigmentation (or both) is a distinct complication after intralesional or intraarticular administration of corticosteroids and is probably due to lymphogenous spread of the steroid suspension.- - - - - - - - - - ranking = 6keywords = hypopigmentation (Clic here for more details about this article) |
7/7. Clinicopathologic correlation of laser lesion expansion after treatment of choroidal neovascularization.The clinicopathologic features of photocoagulation lesion expansion after two separate sessions of krypton red laser for choroidal neovascularization (CNV) in an eye with age-related macular degeneration are presented. The area of expansion is characterized by retinal pigment epithelial atrophy and loss of the photoreceptor cell layer. A thin margin of retinal pigment epithelium hypopigmentation and variable photoreceptor cell layer degeneration also borders the lesion in some areas.- - - - - - - - - - ranking = 1keywords = hypopigmentation (Clic here for more details about this article) |