1/4. blackwater fever treated with artemether.blackwater fever is a rare manifestation of falciparum malaria characterized by sudden intravascular hemolysis followed by fever and hemoglobinuria. We present a case of blackwater fever, having occurred after administration of quinine, which was treated successfully with artemether.- - - - - - - - - - ranking = 1keywords = malaria (Clic here for more details about this article) |
2/4. Epidemiological and clinical aspects of blackwater fever among African children suffering frequent malaria attacks.blackwater fever (BWF), one of the commonest causes of death of Europeans living in africa at the beginning of the twentieth century, but rarely diagnosed since the 1950s, is related to plasmodium falciparum malaria but there is considerable debate and controversy about its aetiology. From 1990 to 2000, the whole population of Dielmo, a village in senegal, was involved in a prospective study of malaria. Three cases of BWF occurred in 3 children aged 4, 7 and 10 years, belonging to a subgroup of children who suffered malaria attacks every 4 to 6 weeks over many years, who had received repeated quinine treatment. The spread of chloroquine resistance, by increasing the use of more toxic alternative drugs, may expose endemic populations to a high incidence of severe side effects of antimalarials.- - - - - - - - - - ranking = 8keywords = malaria (Clic here for more details about this article) |
3/4. A case of black water fever treated with peritoneal dialysis and artemether (quinghaosu derivative).A clinical case of Black Water Fever following plasmodium falciparum infection is reported. The patient had no previous history of malaria and had not taken anti-malarials as prophylasis. He was free from G-6-PD deficiency and abnormal haemoglobins. He had acute intravascular haemolysis, haemoglobinurea and renal failure after the third dose of quinine infusion. His life was saved by peritoneal dialysis and Artemether injection. In in vitro test, his blood haemolysed suddenly in 36 hours when incubated with quinine (10 mg per lit) at 37 degrees C in test tube while control blood took over a week for natural slow haemolysis. Thus quinine plays an important part in the cause of Black Water Fever.- - - - - - - - - - ranking = 2keywords = malaria (Clic here for more details about this article) |
4/4. recurrence of blackwater fever: triggering of relapses by different antimalarials.Five cases of blackwater fever (BWF) are described, all of whom had a history of recent quinine therapy. In two cases a second haemolytic crisis was induced by halofantrine, in one case also a third. Increasing frequency of this syndrome with its dramatic clinical presentation is to be expected as imported P. falciparum infection, parasite resistance to chloroquine and the use of quinine and other related antimalarials become more frequent.- - - - - - - - - - ranking = 5keywords = malaria (Clic here for more details about this article) |