Cases reported "Brain Diseases"

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11/26. survival in cerebro-rhino-orbital zygomycosis and cavernous sinus thrombosis with combined therapy.

    An alcoholic man with uncontrolled diabetes mellitus had right conjunctivitis, facial numbness, and periorbital edema progressing to bilateral visual loss, and left ptosis in association with a large necrotic palatal ulcer due to zygomycosis. The infection progressed to bilateral retinal vein engorgement; left-sided ophthalmoplegia, fixed dilated pupil, and absent corneal reflex; and right-sided ophthalmoplegia, ptosis, and facial nerve paralysis. work-up revealed disease of both ethmoid sinuses and the right maxillary sinus, with bilateral thromboses of the cavernous sinuses. An aggressive combined therapeutic attack (three Caldwell-Luc procedures, exploration of orbit walls, control of diabetes, systemic and local amphotericin therapy) led to survival with a three-year follow-up thus far.
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ranking = 1
keywords = zygomycosis
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12/26. Disseminated zygomycosis masquerading as cerebral lupus erythematosus.

    zygomycosis often occurs in patients with an underlying disease, e.g., diabetes mellitus, leukemia, and lymphoma, or an immunocompromised state. This report discusses a case of a 21-year-old woman with systemic lupus erythematosus complicated by uremia, acidosis, steroid therapy, prolonged antimicrobial therapy, and disseminated zygomycosis.
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ranking = 1
keywords = zygomycosis
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13/26. Brainstem subarachnoid respiratory epithelial cysts: report of two cases and review of the literature.

    Two cystic lesions that were lined by pseudostratified ciliated columnar epithelium containing goblet cells are described. Both lesions were found in the subarachnoid space between the vertebrobasilar arterial system and the brainstem. One cyst was an incidental finding in a patient who died of orbital phycomycosis. The cyst was filled with clear mucinous material. The second cyst presented as a mass adjacent to the brainstem in a woman who had progressive brainstem dysfunction. This lesion showed transition from pseudostratified ciliated columnar epithelium with goblet cells to papillary stratified squamous epithelium, histologic features essentially identical to those of squamous papillomas of the nasal cavity. This lesion was filled with squamous debris. The proposed origin of these lesions is discussed.
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ranking = 4.0908506846149
keywords = phycomycosis
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14/26. Septic abortion complicated by rhinocerebral phycomycosis (mucormycosis). A case report.

    A patient with septic abortion complicated initially by hepatorenal failure and later by rhinocerebral phycomycosis (mucormycosis) is described. It is believed that the outcome was fatal because the patient was diabetic and had been extensively treated with antibiotics.
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ranking = 20.454253423075
keywords = phycomycosis
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15/26. Isolated cerebral phycomycosis presenting as focal encephalitis.

    A patient with features of a focal encephalitis was found to have isolated cerebral phycomycosis. No risk factors for phycomycosis were present, and the diagnosis was made by brain biopsy.
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ranking = 24.545104107689
keywords = phycomycosis
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16/26. Pulmonary and rhinocerebral mucormycosis. Successful outcome with amphotericin b and griseofulvin therapy.

    An ominous prognosis is associated with combined pulmonary and rhinocerebral mucormycosis (phycomycosis). We report the case of a diabetic patient with ketoacidosis who had extensive pulmonary and rhinocerebral mucormycosis that responded satisfactorily to amphotericin b and griseofulvin therapy. The affected lung is completely atelectatic and has remained so for 12 months without evidence of necrosis or abscess formation.
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ranking = 4.0908506846149
keywords = phycomycosis
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17/26. Rhinocerebral mucormycosis.

    Rhinocerebral phycomycosis is a serious and commonly fatal fungal infection. The causative organism, ordinarily a saprophyte, becomes pathogenic in persons who are made susceptible by coexisting, debilitating disease. We report a well-documented case of rhinocerebral phycomycosis where early diagnosis led to successful treatment, and we discuss important aspects of the clinical evaluation and management of such cases.
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ranking = 8.1817013692298
keywords = phycomycosis
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18/26. Cerebral phycomycosis.

    The incidence of phycomycotic infections of the central nervous system (CNS) remains high in diabetic and immunosuppressed patients. Despite increasing awareness of possible CNS fungal infections, the diagnosis during life remains difficult and is most often made at postmortem examination. The present report describes a histologically confirmed case of cerebral phycomycosis diagnosed in life. The findings on computed tomography as well as other radiological diagnostic procedures are discussed.
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ranking = 20.454253423075
keywords = phycomycosis
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19/26. Cranial zygomycosis caused by Saksenaea vasiformis. Case report.

    A previously healthy youth who had sustained severe head trauma and had received steroids and broad-spectrum antimicrobial agents developed a cranial zygomycotic infection with Saksenaea vasiformis. This is the first time this zygomycete has been implicated as a disease agent. Early identification of the fungal infection and subsequent vigorous medical and surgical therapy led to recovery.
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ranking = 0.8
keywords = zygomycosis
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20/26. Rhinocerebral zygomycosis treated with amphotericin b.

    Rhinocerebral zygomycosis is a rare, often fatal opportunistic fungal infection involving the cranial tissues. A diabetic patient with normal humoral and cellular immunity who was successfully treated with amphotericin b and surgery is reported.
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ranking = 1
keywords = zygomycosis
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